ABO blood group (subgroups, discrepancies) Flashcards

1
Q

A subgroups are described by __ in __

A

Von Dungern, 1911

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2
Q

t/f: a subgroups are more common than b subgroups

A

t

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3
Q

__% of all group A (or AB) individuals are A1

A

80%

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4
Q

A1 or A2: weaker subgroup

A

A2

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5
Q

1-8% of __ individuals produce __ in their serum

A

a2 individuals, anti-a1 serum

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6
Q

22-35% of __ individuals produce __ in their serum

A

a2b individuals, anti-a1 serum

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7
Q

A1 cell / A2 cell: has more antigenic sites for the H antigen

A

A2 cell

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8
Q

naturally occurring IgM cold-reacting antibody

A

a1 antibody

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9
Q

unlikely to cause transfusion reaction

A

a1 antibody

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10
Q

clinically significant if reactive at 37C

A

a1 antibody

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11
Q

t/f: h antigen may not be detectable in group a1 individuals

A

t

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12
Q

in the presence of __, almost all of the __ is converted to a1 antigen

A

a1 gene, h antigen

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13
Q

in the presence of __, only some of the __ is converted to a antigens

A

a2 gene, a antigen

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14
Q

seed extracts that agglutinate human cells with some degree of specificity

A

lectins

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15
Q

source of anti-H

A

ulex europaeus

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16
Q

source of anti-a

A

helix pomatia

17
Q

source of anti-a1

A

dolichos biflorus

18
Q

source of anti-b

A

bandeiraea simplicifolia

19
Q

source of anti-m

A

iberis amara

20
Q

source of anti-n

A

molucella laevis, bauhinia purpura

21
Q

source of anti-t

A

arachis hypogaea

22
Q

source of anti-tn

A

salvia sclaera

23
Q

__ subgroups are infrequent

A

b subgroups

24
Q

bombay phenotype was reported by __ in __(year)

A

bhende, 1952

25
t/f: fut 1 - se gene, fut 2 - h gene
f (baliktad)
26
rbcs either completely lack h antigens or have small amounts of h antigen present
parabombay phenotype
27
occur when unexpected reactions are obtained in the forward and/or reverse grouping
ABO discrepancies
28
abo discrepancies can be due to problems with patient's __, __ or both
serum, rbcs
29
t/f: if discrepancies can't be resolved, group o rh (-) may be administered
t
30
most common group of discrepancy
group 1
31
discrepancy commonly seen in newborns, elders, patients with AIDS . leukemia / lymphoma
group 1
32
least frequently encountered discrepancy
group 2
33
discrepancy between forward and reverse groupings resulting in rouleaux formation / pseudoagglutination
group 3
34
discrepancies that may be due to miscellaneous problems
group 4