ABO BLOOD GROUP

Question 1

only blood group system in which an individuals already have antibodies in their serum to antigens that are absent from their red blood cells without any prior exposure to RBCs (transfusion or pregnancy).

Answer 1

ABO BLD GRP

Question 2

Landsteiner’s Rule

Answer 2

If an individual has an antigen, that individual will not have the antibody.

Question 3

ABO Forward Grouping Principle

Answer 3

Detection of Antigens on Patient’s RBC with antisera

Question 4

ABO Reverse Grouping Principle

Answer 4

Detection of Antibodies (Isoagglutinin) Serum of Patients with commercial RBCs

Question 5

Anti-B Reagent in Forward typing contains

Answer 5

acriflavine dye

Question 6

For ABO Abs, Infants-generally too low for detection until they are

Answer 6

3-6 months

Question 7

In ___ individual, the phenotype and genotype are the same.

Answer 7

AB

Question 8

same precursor material from which A, B, and H
antigens all originate

Answer 8

Paragloboside or glycan

Question 9

add sugars to a basic
precursor substance.

Answer 9

glycosyltranferases

Question 10

is present in more than 99.99% of the random population

Answer 10

H gene

Question 11

Refer to phenotype that lacks normal expression of the ABH antigens because of the inheritance of the hh genotype.

Answer 11

Bombay

Question 12

sugars occupying the terminal positions of precursor chain and conferring blood group specificity.

Answer 12

Immunodominant sugars

Question 13

is the precursor substance on erythrocytes when the terminal galactose on the precursor substance is attached to the N-acetylglucosamine in a beta 1→4 linkage.

Answer 13

Type 2

Question 14

precursor substance refers to a beta 1→3 linkage between galactose and N-acetylglucosamine.

Answer 14

Type 1

Question 15

Individuals who are blood group O inherit at least one _____ gene.

Answer 15

FUT 1

Question 16

is sometimes referred to as an amorph and does not
elicit the production of polypeptide transferase

highest concentration of H gene

Answer 16

O blood group

Question 17

codes for the production of the transferase
α-2-L-fucosyltransferase- that modifies the type 1 precursor substance in secretions to form the H substance

Answer 17

FUT 2 (Se)

Question 18

elicits the production of an enzyme called α-2-L-fucosyltransferase that transfers the sugar L-fucose to an oligosaccharide chain on terminal galactose of type 2 chains.

Answer 18

FUT 1 (H)

Question 19

ABH Antigens on RBC COMPOSITION

Answer 19

Can be glycolipids, glycoproteins, or glycosphingolipids

Question 20

A, B, and H Soluble Substances COMPOSITION

Answer 20

glycoproteins

Question 21

ABH Antigens on RBC is synthesized on precursor chain type __?

Answer 21

type 2

Question 22

A, B, and H Soluble Substances are synthesized on precursor chain type __?

Answer 22

type 1

Question 23

seed extracts that agglutinate human cells with some degree of specificity.

Answer 23

Lectins

Question 24

Anti-H lectin

agglutinates O cells and other ABO blood group depending on amount of H antigen

Answer 24

Ulex europaeux

Question 25

source of Anti-A1

agglutinates A1 or A1B

Answer 25

Dolichos biflorus