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ABO > ABO > Flashcards

ABO Flashcards

1
Q

ABO forward reverse grouping test must be done on

A

donors and patients

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2
Q

what is considered to be the major blood group

A

ABO blood group

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3
Q

what is the most frequently performed test in the blood bank

A

ABO bloo group system

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4
Q

Naturally occuring bodies

A

ABO blood group system

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5
Q

what is described by bernstein

A

inheritance of the ABO blood group

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6
Q

when was inheritance discovered by bernstein

A

1924

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7
Q

the inheritance of what genes follows mendelian genetics

A

ABO genes

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8
Q

what terminology if you inherit both A and B genes, threfore you will have AB antigens

A

CODOMINANT

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9
Q

WHAT gene IS CONSIDERED AN AMORPH

A

O genes

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10
Q

no detectable antigen is produced in response to the inheritance of these genes

A

amorph

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11
Q

what blood type are phenotype

A

blood type A, blood type B, blood type O

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12
Q

what are the genotypes

A

AA,AO,BO,OO

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13
Q

First to discover the human blood group system

A

Karl Landsteiner

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14
Q

Individual who first performed the forward and reverse grouping

A

Karl Landsteiner

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15
Q

LANDSTEINERS LAW

A
  1. The antigen on the RBC determines the blood group
  2. The corresponding antibody is never found in the individuals serum
  3. the opposite antibody is always present in the individuals serum
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16
Q

what antibody is naturaly occuring

A

ABO Antibodies

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17
Q

PREDOMINANTLY IgM

A

ABO antibodies

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18
Q

what is the exception in the ABO antibodies which is IgG in nature

A

anti-AB

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19
Q

why should we not perform reverse groupin on babies

A

production of ABO is not yet high

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20
Q

Detectable titers in ABO atibodies

A

3 to 6 months

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21
Q

what is the peak of ABO antibodies

A

5-10 years

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22
Q

what causes rapid intravascular hemolysis

A

ABO antibody

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23
Q

what antibody is produced by blood group A, B, AB,O

A

ANTI-B, ANTI-A, NONE, ANTI A, ANTI B, ANTI AB

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24
Q

CAN WE PERFORM FORWARD TYPING ON BABIES

A

YES

25
Q

ABO ANTIGEN IS ALREADY AVAILABLE IN FETUS ON WHAT DAY

A

37TH DAY OF FETAL LIFE

26
Q

WHAT ANTIGENS IS DEVELOPED FROM PRECURSOR H SUBSTANCE

A

A ANTIGEN
B ANTIGEN

27
Q

SPECIMEN FOR BLOOD TYPING

A

SALIVA, PANCREATIC SECRETION, GASTRIC SECRETION

28
Q

WHAT IS THE MOST COMMON BLOOD TYPE

A

O AND A

29
Q

RAREST BLOOD TYPE

A

AB (ROYAL BLOOD)

30
Q

WHAT ARE THE ANTIGEN PRESENT IN BLOOD TYPE A,B,AB,O

A

A and H
B and H
AB and H
O and H

31
Q

Result from the interaction of genes of three separate loci

A

ABO, H, Se

32
Q

precursor structure on which A and B are made

A

H antigen

33
Q

what gene are closely linked and are located on chromosome 19

A

H and Se gene

34
Q

ABH antigen precursor in type 2 substance

A

RBC

35
Q

ABH antigen in type 1 precursor substance

A

secretions

36
Q

what is the enzyme in the formation of H ANTIGEN

A

alpha-2-L fucosyltransferase

37
Q

what is the sugar present in the formation of A antigen

A

N-acetyl d-galactosamine

38
Q

what is the sugar present in the formation of the B antigen

A

d-galactose

39
Q

what is the product of alleles at ABO and Hh loci

A

Secretor gene

40
Q

how many percent of the population is secretors

A

80 percent

41
Q

sese or SESE are the individuals that are non secretors

A

sese

42
Q

wht are the fluids in which A,B, AND H substance can be detected in secretors

A
  1. saliva
    2.tears
    3.urine
    4.digestive juices
    5.bile
    6.milk
  2. amniotic fluid
  3. pathological fluid
43
Q

seed extract that agglutinate human cells with some degree of specificity

A

lectin

44
Q

genotype of blood group O

A

OO

45
Q

Anti H antisera

A

ulex europaeus

46
Q

blood group A genotype

A

A, H

47
Q

LECTIN of Blood group A

A

dolichos biflorus

48
Q

what antigen is capable of crossing the placenta

A

IGg

49
Q

antigen of blood group A

A

A,H

50
Q

antibody of bloo group A

A

anti-B

51
Q

genotype of blood group B

A

B,H

52
Q

Bandeiraea simplicifolia is revised to

A

Griffonia simplicifolia

53
Q

what is the genotype of blood group AB

A

AB

54
Q

antibodies in blood group AB

A

none

55
Q

why is H very little in the antigen of blood group AB

A

because there is already 2 sugars added to the original structure

56
Q

greatest amount of reactiviy to the least amount

A

0>A2>B>A2B>A1>A1B

57
Q

recessive gene in bombay phenotype

A

hh

58
Q

also called OH phenotype

A

Bombay phenotype

59
Q

appears as group O on forward typing

A

Bomby phenotype

ABO (2 decks)

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