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Prudent use > Ab in Swine > Flashcards

Ab in Swine Flashcards

1
Q

How can Enrofloxacin be given to swine?

A

IM & PO

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2
Q

How is Marbofloxacin given in swine?

A

IM

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3
Q

how is ceftiofur given in swine

A

im

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4
Q

how is Cefquinome given in Swine?

A

im

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5
Q

How can colistin be given in Swine?

A

im or po

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6
Q

Enrofloxacin, Marbofloxacin, Ceftiofur, Cefquinome are category?

A

B

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7
Q

how can amox+clav be given in swine

A

po & im

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8
Q

1st choice in swine E.Coli Enteritis?

A

Gentamycin

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9
Q

Gentamycin has a … absorption in gut (swine)

A

poor absorption (5%) –> high C in gut

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10
Q

Which one is broad spectrum & bacteriostatic, but bactericidal in the resp tract

  • gentamycin
  • amox+clav
  • florfenicol
  • lincomycin
A

florphenicol

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11
Q

flophenicol can be given (swine):

  • po
  • im
  • both
  • none
A

both

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12
Q

lincomycin can be given (swine)

A

po & parenteral

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13
Q

spectinomycin & lincomycin should given

  • orally
  • parenterally
A

parenterally - poor oral absorption of spectinomycin

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14
Q

which ones is bacteriostatic, but bactericidal in the lung?

  • Tiamulin
  • valnemulin
  • tylvalosin
  • Tilmicosin
  • Macrolides
A

Tiamulin & valnemulin & Macrolides

reaches high concentration in the lung

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15
Q

Which are the 2 forms of Tylosin ?

A

Tylosin - tartarate

Tylosin - phosphate

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16
Q

Which Tylosin should be used in resp tract infection?

  • Tylosin - tartarate
  • Tylosin - phosphate
A

Tylosin tartarate

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17
Q

Which Tylosin should be used in GIT infection (proliferative enteritis)?

  • Tylosin - tartarate
  • Tylosin - phosphate
A

Tylosin Phosphate

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18
Q

Which one has the worst absorption?

  • Tylosin - tartarate
  • Tylosin - phosphate
A

Tylosin phosphate

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19
Q

Tylvalosin should be given

  • po
  • im
  • sc
A

po

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20
Q

Tylvalosin is active against

  • mycoplasma
  • lawsonia intracellularis
  • brachyspira hyodysenteriae
  • all
A

all

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21
Q

What is an side effect if tilmicosin is used parenterally ?

A

cardiotoxic effect

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22
Q

tilmicosin should be given…

A

… PO

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23
Q

Tulathromycin should be given

  • iv
  • im only
  • iv and im
  • sc
A

im only

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24
Q

tulathromycin is effective against

A

mycoplasma + gram neg fastidious

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25
Q

tildipirosin should be given

A

im

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26
Q

Can Penicillin be given Po in Swine?

A

no, it is off label

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27
Q

Amox and PotSA can be given :

A

PO and parenteral

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28
Q

Which lesion is caused by Cl.perfringens C in Swine?

  • ulcerative enteritis
  • necrotic enteritis
A

necrotic enteritis

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29
Q

Why can Penicillins be used in Cl.perfringens C infections in swine?

A

Cl.perfringens C doesn’t produce beta lactamase

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30
Q

Which penicillin cannot be used in Cl.perfringens C infections in swine?

A

Phenoxymethyl penicillin - off label

31
Q

Which penicillin should be given PO in Cl.perfringens C infections?

A

Amoxicillin

32
Q

In what age can swine get sick of Cl.perfringens C ?

A

It is a disease of suckling pigs

33
Q

Escherichia Coli in swine - age class

A

suckling piglets and weaned pigs

34
Q

E.Coli Strains are usually resistant to which catergory ?

A

AB of category D

35
Q

Which are the big guns against E.Coli?

A

Ceftiofur
Cefquinome
Enrofloxacin
Colisitin

–> only after AB susceptibility test

36
Q

Why should we be careful with gentamycin in E.Coli infections

A

E.Coli strains can easily develop resistance against gentamycin

37
Q

What causes ileitis in swine?

A

Lawsonie intracellularis

38
Q

3 main causes of Polyserositis

A

Glässer’s disease - haemophilus suis
Mycoplasma hyorhinis
Staphylococcus suis

39
Q

which ab is effective against all 3 causes of polyserositis in swine?

A

Florphenicol

40
Q

Which AB are effective against Glässers and Mycoplasma hyorhinis?

41
Q

Which are the best AB against Polyserositis in Swine, but are CIA?

A

Ceftiofur
Cefquinome
Enrofloxacin

42
Q

PRCD - porcine respiratory disease complex causes

A
  • actinobacillus pleuropneumonia
  • pasteurella multocida
  • bordetella bronchiseptica
  • glässerella parasuis
  • streptococcus suis
  • mycoplasma hyorhinis
43
Q

Acute meningitis caused by

A

Streptococcus suis

44
Q

Acute meningitis is caused by streptococcus suis, how is amoxicillin helping?

A

amoxicillin parenterally –> reach appropriate concentration in the liquor <=> due to damaged meniges

45
Q

Mycoplasma Hyopneumoniae löst eine..

A

… bronchointerstitial pneumia aus

46
Q

enzoonotic pneumonia

A

catarrhal - purulent or suppurative bronchopneumonia

47
Q

Where can we find macroscopic lesion in case of mycoplasma hyopneumoniae?

A

apical
cardiac
intermediate
diaphragmatic lung lobe

48
Q

Which AB is the best against Mycoplasma hyopneumoniae?

  • tylvalosin
  • tylosin
  • doxycycline
  • tilmicosin
A

tylvalosin

49
Q

Which AB is the best against Mycoplasma hyopneumoniae?

  • Lincomycin
  • Linco- spectino
  • Tulathromycine/gamitromycin
  • florfenicol
A
  • Tulathromycine/gamitromycin
50
Q

Which AB is the best against Mycoplasma hyopneumoniae?

  • Lincomycin
  • Linco- spectino
  • Tiamulin/valnemulin
  • florfenicol
A

Tiamulin/valnemulin

51
Q

Which one is not active against Gram -, but against Myco?

  • tylvalosin
  • tilmicosin
  • tylathromycin
A

Tylvalosin

52
Q

Which one is active against Gram -, Myco hyopneumonia and APP?

  • tylvalosin
  • tilmicosin
  • tulathromycin
A

tulathromycin/ Gamithromycin

rapid absorption from inj, extensive diffusion to tissues, slow elimination

53
Q

Which one is variably active Myco hyopneumonia, but active against APP and pasteurella multocida ?

  • tylvalosin
  • tilmicosin
  • tulathromycin
A

Tilmicosin

54
Q

How old are swines infected by Actinobacillus Pleuropneumonia?

  • 0-4 weeks
  • 4-8 weeks
  • 8-12 weeks
  • > 12 weeks
A

8- 12 weeks old

55
Q

Best Ab choice in case of actinobacillus pleuropneumoniae (APP)

  • Amox
  • Amox - Clav
  • Ceftiofur
  • Cefquinome
A

Amox (>80%)

56
Q

Best Ab choice in case of actinobacillus pleuropneumoniae (APP)

  • Amox
  • PotSA
  • none
  • both
57
Q

Which drugs have an outstanding effect against actinobacillus pleuropneumoniae, but should be used as last resort?

A

Fluoroquinolones + 4G cephalosporines

Enrofloxacine & Marbofloxacin

58
Q

Which drugs have a good effect against APP, but should be used as last resort, after susceptibilty test?

A

Tetracyclines –> frequent resistance

59
Q

Symptomatic treatment of MMA, PDS with which drugs?

A

Meloxicam & flunixin - antiendotoxic effect

60
Q

Gentamycin absorble in gut?

  • yes, good absorption
  • no, no absorption in gut
A

no –> im

61
Q

Which drug is eliminated by milk?

  • amox + clav
  • gentamycin
  • florphenicol
A

florphenicol –> damage for piglets

62
Q

which drug cannot be used in lactating sows, if there is a MMA, PDS?

  • amox + clav
  • gentamycin
  • florphenicol
A

florphenicol

63
Q

Which is the best drug in case of E.coli caused PDS/MMA?

  • amox + clav
  • gentamycin
  • florphenicol
A

amox + clav
gentamycin – no abs in gut
florfenicol – excretion by milk

64
Q

Which drug cannot be used in E.Coli cause PDS/MMA?

  • Colistin
  • Fluoroquinolones
  • 3&4 gen Cephalosporins
A

Colistin –> not absorbed by gut after po & parenteral cause many side effects

65
Q

What do we need to do if we want to use 3&4 gen Cephalosporins in case of E.Coli caused PDS/MMA?

A

prove bacteria is resistant to cat.D&C

prove bacteria is susceptible to category B

66
Q

Which one has a good effect against Gram - and Gram + bacteria ?

  • Fluoroquinolones
  • 3&4 gen Cephalosporins
  • both
  • none
67
Q

Age swine in case of Staphylococcus Hyicus infection?

  • suckling
  • weaned
  • suckling and weaned
A

suckling and weaned

68
Q

Can we use Amox against staphylo hyicus?

A

no, because they produce beta lactamase

69
Q

3 best drugs against staphy hyicus?

A

tylosin
lincomycin
PotSA

70
Q

Can we use amox + clav in staph hyicus?

A

yes, it is active but need high concentration to reach the skin

71
Q

Erysipelothrix rhusiopathiae occurs:

  • upper airway
  • lower airway
  • both
A

upper resp tract

72
Q

Against which drugs are Erysipelothrix rhusiopathiae always susceptible?

  • penicillin
  • amox
  • both
73
Q

Mycoplasma hyosynoviae causes arthritis in swine, which drugs reaches the appropriate concentration in the synovia?

A

Tylvalosin
Tulathromycin
Gamithromycin
Florfenicol

Prudent use (3 decks)

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