Ab in Poultry Flashcards

1
Q

How can Colibacillosis spread to young chicks?

A
  • in embryonic stage - egg shell is infected (goes through pores)
  • inhalation in hatchery (dust)
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2
Q

How can Chicks get infected by Colibacillosis?

A
  • infectious predisposing factor needed (mycoplasma)
  • CRD -> fibrinopurulent air sacculitis –> scrambled egg
  • > pericarditis, perihepatitis
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3
Q

Colibacillosis in chicken cause:

  • pericarditis
  • perihepatits
  • fibrinopurulent airsacculitis
  • none
  • all
A

all

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4
Q

Salpingitis can be caused by

  • pasteurella
  • salmonella
  • mycoplasma
  • all
A

all

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5
Q

Fowl Cholera is caused by

  • E.coli
  • Pasteurella multocida A
  • Ornithobacterium rhinotracheale
  • Clostridium
A

pasteurella multocida A

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6
Q

which animals are more susceptible to fowl cholera?

  • Duck, Goose
  • Chicken
  • Turkey
A

Waterfowls - Duck & Goose
more sensitives because in correlation with dramatic weather change
duck goose > turkey > chicken

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7
Q

Fowl Cholera lead to ?

A

Petechiae, suffusions, serosal bleedings

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8
Q

Ornithobacterium Rhinotracheale affects:

  • lower resp tract
  • upper resp tract
  • none
  • both
A

upper resp tract –> mucus & fibrin –> asphyxia

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9
Q

Which species is the most affected by Ornithobacterium rhinotracheale?

  • turkey
  • chicken
  • waterfowls
  • all
A

turkey

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10
Q

Cl.Colinum causes:

  • ulcerative enteritis
  • necrotic enteritis
  • both
  • none
A

ulcerative enteritis

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11
Q

Cl. perfringens A/C causes:

  • ulcerative enteritis
  • necrotic enteritis
  • both
  • none
A

necrotic enteritis

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12
Q

Which species is most affect by Cl.Colinum

  • chicken
  • quail
  • turkey
  • none
  • all
A

all

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13
Q

Which species is most affecte by Cl.perfringes A/C

  • chicken
  • quail
  • turkey
  • none
  • all
A

chicken

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14
Q

Staphylococcus aureus leads to ..?

A

first: septicaemia
delayed disease situation: arthritis
dermatitis

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15
Q

M.meleagridis

  • > more pathogenic in?
  • > infection of?
A
  1. in turkeys

2. infection of air sac -> bones -> neck, vertebrae -> CNS signs

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16
Q

M.gallisepticum affects?

  • turkeys
  • chicken
  • both
  • none
A

both

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17
Q

what is the role of clavulanic acid?

A

“suicide molecule” - prevents beta lactamase from destroying amoxicillin –> amox will be more effective

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18
Q

Sulphonamide + ..?

  • spectinomycin
  • gentamycin
  • Trimethoprim (diaminopyridines)
  • none
A

sulphonamide + trimethoprim (diaminopyridines)

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19
Q

Lincomycin +…?

  • spectinomycin
  • gentamycin
  • Trimethoprim (diaminopyridines)
  • none
A

Lincomycin + Spectinomycin

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20
Q

Amoxicillin + …?

  • spectinomycin
  • gentamycin
  • Trimethoprim (diaminopyridines)
  • none
A

Gentamycin (Aminoglycoside)

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21
Q

streptomycin + Tetracycline have:

  • total inhibition
  • mild inhibition
A

mild inhibition

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22
Q

Which Ab are not available for oral use, because they are destroyed by stomach acid ?

  • broad spectrum penicillin
  • narrow spectrum penicillin
  • Penicillinase stable penicillin
  • penicillins acting against pseudomonas
A

narrow spectrum penicillin

23
Q

Which narrow spectrum penicilin can used orally? (exception of the group)

  • Benzylpenicillin K/Na
  • Benzylpenicillin procaine
  • Phenoxymethyl penicillin
  • Benzylpenicillin benzathine
A

Phenoxymethyl penicillin

24
Q

Indication of narrow spectrum penicillin?

A

Cl.perfringens
swine erysipelas
streptococcus
fowl cholera (pasteurella multocida)

25
Q

Oral absorption of amoxicillin:

  • poor
  • good
  • mild
A

good - 60-80%

26
Q

Water acidifiers:

  • reduce bad bacteria in the gut
  • good bacteria in the gut will continue to grow
  • decrease efficacy of clavulanic acid
  • all
  • none
A

all

27
Q

Good bacteria in the gut:

  • lactobacillus
  • enterobacilli
  • none
  • both
A

both

28
Q

First choice medication in P.multocida & fowl cholera?

A

amoxicillin

29
Q

Indication of amoxicillin in poultry?

  • P.multocida, Fowl cholera
  • Enterococcus
  • O.rhinotracheale
  • all
A

all

30
Q

Aminoglycosides are:

  • hydrophilic, polarised
  • hydrophobic, polarised
A

hydrophilic polarised

31
Q
Aminoglycosides have an oral absorption of :
> 5%
< 5%
> 15%
< 15%
> 50%
< 50%
A

<5% - bad oral absorption

32
Q

Aminoglycosides are eliminated by:

  • liver
  • kidney
  • Bile
A

kidney

33
Q

Aminoglycosides bind to:

  • renal cortex
  • renal medulla
  • renale capsule
A

renal cortex

34
Q

Which is true?
A) Spectinomycin eliminates mycoplasma & lincomycin eliminates Coli
B) Spectinomycin eliminates E.coli, lincomysin eliminates Coli
C) Spectinomycin eliminates E.coli, lincomysin eliminates mycoplasma
D) Spectinomycin eliminates mycoplasma, lincomysin eliminates Coli mycoplasma

A

C) Spectinomycin eliminates E.coli, lincomysin eliminates mycoplasma
synergistic

35
Q

Colistin..

A

.. binds to LPS –> destroyes mb (direct killing effect)

36
Q

Which one is true :
A) Colistin is negatively charged and Outer layer of membrane is negatively charged
B) Colistin is positively charged and Outer layer of membrane is negatively charged
C) Colistin is negatively charged and Outer layer of membrane is positively charged
D) Colistin is positively charged and Outer layer of membrane is positively charged

A

B) Colistin is positively charged and Outer layer of membrane is negatively charged

37
Q

Which one has the best absorption rate?

  • otc
  • ctc
  • doxycyline
A

doxycycline

37
Q

Which one has the best absorption rate?

  • otc
  • ctc
  • doxycyline
A

doxycycline

38
Q

Indication of Tetracyclines:

  • fowl cholera
  • o.rhinotracheale
  • mycoplasmosis
  • bordetella avium
  • all
A

all

39
Q

For Mycoplasma gallisepticum & m.synoviae, which one is correct:

  • Tilmicosin < tylosin < tylvalosin
  • tylosin < tilmicosin < tylvalosin
  • tylosin < tylvalosin < tilmicosin
  • tilmicosin < tylvalosin < tylosin
A

Tilmicosin < tylosin < tylvalosin

40
Q

O.rhinotracheale

  • Tilmicosin &laquo_space;tylosin < tylvalosin
  • tylosin &laquo_space;tilmicosin < tylvalosin
  • tylosin &laquo_space;tylvalosin < tilmicosin
  • tilmicosin &laquo_space;tylvalosin < tylosin
A

tylosin &laquo_space;tilmicosin < tylvalosin

41
Q

almost total resistance of pasteurella multocida & E.coli against:

  • tetracyclines
  • macrolides
  • both
  • none
A

macrolide

42
Q

Lincomycin indication

A

Staphylococcosis
c.perfringens
mycoplasmosis

43
Q

Tiamulin indication

  • none
  • both
  • mycoplasmosis
  • o.rhinotracheale
A

both

44
Q

Which one has a nitrogen group?

  • florphenicol
  • chloramphenicol
  • thiamphenicol
  • all
A

chloramphenicol –> dose independent aplastic anemia in hu

the other ones contain methyl sulfid group instead

45
Q

Fluoroquinolones resistance of E.Coli

  • poultry&raquo_space; swine
  • swine&raquo_space; poultry
A
  • poultry&raquo_space; swine
46
Q

PotSA toxicity leads to

A

bone marrow suppression
Vit K deficiency - bleedings
anemia

47
Q

Resistance against Tetracyclines:

A

> 40-90%

48
Q

Resistance against fluoroquinolones:

A

60-80%

49
Q

1 st line meds for Pasteurella multocida

  • Amox
  • florfenicol
  • none
  • both
A

both

+ doxy, potSA

50
Q

2nd line meds fowl cholera

  • enrofloxacin
  • tylvalosin
  • both
  • none
A

both

51
Q

Amox, doxy & florfenicol are 1st line drugs in?

A

fowl cholera

o.rhinotracherale

52
Q

1st line drug in case of Cl.perfringens

  • Benzylpenicillin K/Na
  • Benzylpenicillin procaine
  • Phenoxymethyl penicillin
  • Benzylpenicillin benzathine
A

-Phenoxymethyl penicillin