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BACTE LEC PRELIMS > AAAST 2 > Flashcards

AAAST 2 Flashcards

1
Q

Superinfection means

A

Destruction of normal flora

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2
Q

Hirap sa gram neg organisms

A

Beta lactam drug

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4
Q

Increase permeability, acts like detergent

A

Polymyxins

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6
Q

Action against gram posi and nega bacte

A

Broad spectrum

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7
Q

Methicillin and oxacillin are what kinds of penicillin

A

Penicillinase Resistant Penicillins

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8
Q

Another name for peptidoglycan layer

A

Murein layer

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10
Q

Cephalosporin is what kind of drug

A

Beta lactam drug

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11
Q

MOA: binds to terminal D ala D ala

A

Glycopeptides

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15
Q

PBP means

A

Penicillin binding Protein

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16
Q

Drug for anaerobes, microaerophiles, protozoans

A

Metronidazole

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17
Q

Limited to gram positive organisms because it is a large molecule

A

Glycopeptide

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18
Q

Penicillin G pano pinapasok

A

Intramuscular

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19
Q

Recycle certain metabolites

A

Bacitracin

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20
Q

Cycloserine MOA

A

inhibit synthesis of peptidoglycan precursors in cytoplasm

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21
Q

Prevent dihydrofolate reductase

A

Trimethoprim

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22
Q

Bind and interfere with DNA gyrase and Topoisomerase IV

A

Fluoroquinolones

23
Q

PABA means

A

Para amino benzoic acid

24
Q

Last resort to Pseudomonas aeruginosa and Acinetobacter (?) infections

A

Polymyxins

25
Q

First line drugs antimycobacterial agents (3)

A

Isoniazid, rifampicin, pyrazinamide

26
Q

Generation of cytotoxic compounds and free radicals that disrupt DNA

A

metronidazole

27
Q

Block formation of 7,8 dihydropteroate

A

Sulfonamides

28
Q

Important precursor in dna synthesis of bacteria

A

Folate

29
Q

Inhibit translation through inhibition of elongation step by binding to 23s RNA..

A

Macrolides

30
Q

Inhibit mycolic acid

A

Antimycobacterial agents

31
Q

Cyclic polypeptides

A

Polymyxins

32
Q

Oral medication penicillin type

A

Penicillin V

33
Q

MOA Formation of covalent complexes with enzymes that generate peptidoglycan molecule

A

Beta lactam drugs

34
Q

NAG and NAM is in

A

Peptidoglycan layer

36
Q

Clostridium dificile is related to what infection

A

Superinfection

BACTE LEC PRELIMS (2 decks)

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