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BACTE LEC PRELIMS > AAAST 1 > Flashcards

AAAST 1 Flashcards

1
Q

Used together with penicillins often

A

Aminoglycosides

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3
Q

Calcium chelated

A

Tetracycline

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4
Q

Antimicrobial susceptibility has been lost

A

Clinical resistance

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5
Q

Short dna sequences - transposable element

A

Insertion sequences

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6
Q

Inhibit protein synthesis (2)

A

Tetracycline and dexocycline

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8
Q

Reduced susceptibility of an organism to a microbial agent

A

Biological resistance

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9
Q

Formation of persister cells

A

Biofilms

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11
Q

Inherent resistance of Gr (-) bacteria to Vancomycin

A

Impermeability; intrinsic resistance

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12
Q

INTRINSIC OR ACQUIRED RESISTANCE

Decreased penetration of antibiotic

A

Intrinsic

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13
Q

Production of enzymes that destroy antimicrobial agents

A

Enzyme inactivation

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14
Q

INTRINSIC OR ACQUIRED RESISTANCE

Embedded in exopolysaccharide matrix

A

Intrinsic

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15
Q

Acquired resistance happen due to

A

Abuse of antibiotic

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16
Q

MRSA means

A

Methicillin Resistant Staphylococcus aureus

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17
Q

INTRINSIC OR ACQUIRED RESISTANCE

Resistance to beta lactam drugs

A

Acquired

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18
Q

ESBL

A

Extended Spectrum Beta Lactamase

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19
Q

What r the ESBLs

A

Enterics

20
Q

Drug of choice for MRSA

A

Vancomycin

21
Q

Jumping genes

A

Transposons (?)

22
Q

INTRINSIC OR ACQUIRED RESISTANCE

Glycopeptide resistance

A

Acquired

23
Q

For mycoplasma, treponemes, rickettsia

A

Macrolides

24
Q

INTRINSIC OR ACQUIRED RESISTANCE

Biofilms

A

Intrinsic

25
Q

Enzymatic alterations involving a plasmid borne variant of an enzyme

A

Resistance to quinolones

26
Q

Inhibit protein synthesis by interacting with 23s rRNA

A

Linezolid

28
Q

Most important strategy of bacteria to spread resistance

A

Lateral gene transfer

29
Q

Resistance to folate pathway inhibitors mean

A

Target site substitution

31
Q

Causes pseudomembranous colitis

A

Clindamycin

32
Q

Linezolid is a

A

Oxazolidinones

33
Q

Used before for typhoid

A

Chloramphenicol

34
Q

Limited spectrum of action

A

Narrow spectrum

35
Q

Mobile genetic elements

A

Integrins

38
Q

Meaning of resistance to macrolides

A

Altered cell wall precursors unable to bind to vancomycin

BACTE LEC PRELIMS (2 decks)

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