A patient W Fever,seizures ,traumatic Brain Injury,Poisoning Flashcards

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1
Q

What is the normal temp of a patient
Abnormal temp is ?
What do you do for a child w abnormally high temperature
What about an adult
What are the causes of fever
What Iv fluids will you give to kids and adults
Why do you give IV fluids
How much fluid does your body need in a day

A

36.1-37.1 is normal
Above 37.5 is abnormal

Make patient stable by reducing the fever and reducing pain if there’s pain(for a child-tepid sponge and NSAID. For an adult-IV NSAID )
Do ABDCE
Assess the patient(physical exam and history )
JACCOL HTN
J-Jaundice
A-anemia or pallor
C-cyanosis
C-clubbing 
O-odema
L-lymphadenopathy 
H-hydration or dehydration 
T-temperature 
N-nutrition status 
Do investigations 
Give treatment(anti-pyretics,IV fluids and others depending on the symptoms or what you think is causing the fever)
Causes of fever should be grouped jn classifications
-Infection 
Fungal,bacterial,viral,parasitic
-trauma
-hematological
-Idiopathic
-Neoplastic
-Allergic reactions
-CNS injury 
-Hyperthyroidism 
-Thromboembolic disease
-Inflammatory diseases 
-drug induced fever

Adults- IV fluids : N/S, R/L, DNS 5%

Kids-1/5th NS in 4.3% dextrose

To replace fluids
To maintain fluids

  1. 0
  2. 5
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2
Q

What investigations will you do for a patient w fever,state their normal ranges

A

-FBC:
ESR shows recent inflammation but isnt a good marker for inflammation
C reactive protein is better in checking acute inflammation
Leukocytes ;
Lymphocytes-indicate a viral infection
Neutrophils-bacteral infection
Eosinophils-parasitic infection
Urine R/E
Stool R/E
BF (blood film)or MPC (malaria parasite count)to check for malaria parasites
Thin- A thin blood smear will identify the species of the malaria parasite.
Thick-Thick blood smears are most useful for detecting the presence of parasites, Or number of parasites
In the blood

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3
Q

How do you calculate maintenance dose of IV fluids for adults and neonates and infants or toddlers

How do you calculate replacement dose?
If you vomit once as a child or an adult how much is estimated to be loss?
If you pass watery stools once as an adult or a child how much fluid is estimated to be lost?

A

Adults:
You use 70kg so 50mls per kg

Neonates:
60mls per kg

Day 2 of giving fluids increase by 20 mls so it’ll be 80 mls per kg

Day 3,increase by 20 so 100 mls per kg
Day 4,increase by 20 so 120mls and so on
So every day increase by 20mls and your limit should be 180 mls

Infants or toddlers:
100mlsper kg

Replacement dose:
Calculate the loss and replace according to the amount estimated to be lost then after that calculate maintenance dose

Watery stool:
Adult- 500mls
Child-125mls

200 or 250? I’m confused saf

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4
Q

Give four examples of baseline tests or investigations
What are diagnostic tests and definitive tests
Which type of test is done first

A

A) A complete blood test: it generally includes the red cell count, Hi, hct, and corpuscular values. A white cell count with differential. Blood Urea and Creatinin( as well as Creatinine clearance.

B) Liver function test : (Enzymes, etc)

C)Electrolites( Na, K, Cl, etc)

D) Lipid Studies (HDL, LDL, CHOL.,TRIGS,etc

E) Fasting blood glucose

F) Random Urine

G) general blood chemistry

Diagnostic tests are used to confirm or rule out conditions and diseases.
Definitive: final diagnosis that is made after getting the results of tests, such as blood tests and biopsies, that are done to find out if a certain disease or condition is present
1.Baseline tests
2.Diagnostic tests
3.Definitive tests

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5
Q

A high hematocrit as a marker under FBC means what?

A

A higher than normal hematocrit can indicate: Dehydration. A disorder, such as polycythemia vera, that causes your body to produce too many red blood cells. Lung or heart disease

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6
Q
Which people are ideally supposed to treat seizures but which people treat it in Ghana
What is a seizure
What is epilepsy 
What is a convulsion
Classify seizures and explain them 
What is consciousness 
Give one sign of seizures in neonates

How long should seizures last?
When will a seizure be an emergency?
What is status epilepticus

A

Psychiatrists treat seizures in Ghana cuz most epilepsy patients have associated psychiatric problems or signs but ideally it’s to be treated by a neurologist

Seizure:uncontrollable electrical discharges in the brain which could be limited to one hemisphere or both

Epilepsy:recurrent seizures
Convulsions: tonic clonic seizure

Types:
According to the international alliance against seizures:
1. Focal or partial seizures-originate from one hemisphere of t brain
2. Generalized seizures -originates from both hemispheres of the brain

Focal seizures can be dviiddd into 3.simple and 4.complex seizures
Simple you don’t lose consciousness during the seizure but complex you lose consciousness (if a patient is well oriented to person,place and time the person is conscious)

  1. focal or partial to generalized seizure
  2. Motor seizure- causes motor activity(increased tone and Increased movements )
  3. Non motor seizure-patient starts behaving differently during the seizure ,patient senses some peculiar smell before the seizure or a familiar place comes to mind before the seizure comes
  4. Tonic clonic seizures or grand mal seizure : increased tone with uncontrolled movement
  5. Tonic seizure: increased tone and patient becomes still then there’s increased tone again without uncontrolled movement
  6. Clonic seizure: patient gets uncontrolled movements all of a sudden
  7. Myclonic- groups of muscles get uncontrolled movement not the whole body
  8. Atonic seizures- lose bilateral muscle control. All muscle groups lose control
  9. Petit mal or absence seizure: patient becomes absent minded for some secs staring in a particular direction and doesn’t hear whatever is said to them till the seizure is over

Rapid eye blinking
6and7 are based on what is observed by on lookers

Less than 5 minutes

Any seizure that lasts for more than five mins is an emergency

SE- seizure lasts for more than five minutes or within a period of five minutes you’re having multiple seizures and SE is an emergency

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7
Q

What are the causes of Seizures:
VITAMINS
What is the most common cause of seizures in the elderly and in kids

A

V- vascular causes example hemorrhagic shock,hypoperfusion,hypertensive
Encephalopathy,hypertension
I- infections example meningitis,brain abscess,encephalitis

T-Toxins or trauma example bacterial toxins,drugs ,uremia due to CKD

A- Arteriovenous malformations-problem with arteries and veins in the brain

M-metabolism or metabolic abnormalities
Example,electrolyte
Imbalance, Hyperglycemia,hypoglycemia 
I-Idiopathic causes 
N-neoplastic causes (brain tumors,space occupying lesions )

Elderly- UTI
Kids- infections especially cerebral
Malaria

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8
Q

How do you manage a seizure patient in emergency
(Investigations,other procedures)
Max dose of diazepam is what for an adult
What do you do if RBS is low
What is lymphocytosis
Wha investigations will you do for a seizure patient

A
  1. Call for help
  2. Remove objects around from patient to make environment safe
  3. To stabilize patient,give 1-3 doses of benzodiazepines which are first line drugs for seizures example lorazepam,diazepam. Thirty minutes between each dose
    Give the IV drug through the anus if there’s no line during the seizure
    b. Give two doses of barbiturates if the first line doesn’t work
    Thirty minutes interval between each dose
    C. If barbiturates don’t work, give midazolam
    If still give propofol and only in extreme cases and be monitoring this patients airway and make an an anesthesia person give it and monitor the patient
    It is not given at home
    In an ideal situation it should be given in a theatre cuz you need to monitor the patients vitals
    PAs don’t give propofol
    So if you give all the drugs and still,refer and make sure patient is referred safely on oxygen,IV lines secure,arrange for an ambulance,let a nurse accompany the patient
    4.ABCDE- set line,take samples and send to lab
    D- RBS and out patient in recovery position( left lateral side)
  4. Find definite cause and correct it when the investigations come
    Put patient on seizure chart to check the number of times the patient gets the seizure and the duration of each seizure and every 15 minutes check if patient gets a seizure
    If no seizure, check every thirty minutes
    If still no seizure check every one hour

RBS,FBC,BF,BUE,lumbar puncture, Urine RE to check for UTI
CT scan
MRI

High lymphocytes and penia is low

20 mg for adults, give 20 mg diazepam diluted in 500 mls of N/S for kids
Give 50 mls of 50 percent dextrose slowly through IV not fast then flash w normal saline

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9
Q

What is a TBI
Damage to the Brian can be what or what
What processes injure the brain
Swelling can cause what?

A

A form of acquired brain injury that occurs when a sudden trauma causes damage to the brain . Loss of consciousness does not need to occur

Focal: confined to one area of the brain
Diffuse: involves more than one area of the brain
TBI can result from a. A closed head injury(injury not visible to the eye. Object doesn’t break through skull)
b. Penetrating head injury (object pierces through skull

  • bruising (bleeding) : brain tissue is squished against skull and blood vessels may tear . When they tear they release blood into areas of the brain in an uncontrolled
    -tearing: part of the brain is taken away. this leads to damage to nerve cells
    -Swelling: swollen brain mass pushes against the skull. Fluid accumulation the cells of the brain. primarily form inflammatory response to injury leading to increase ICP
    The skull has a fixed space so when there’s swelling of the brain the brain tries to look for an outlet to contain its increased size so it pushes through the foramen magnum ( hole under the skull where the spinal cord meets the skull) . Herniation occurs when the swollen brain push through th foramen magnum . The medulla Oblongata comes down and th vertebrae pushes against the medulla oblongata. Aiding respiratory Centre to shut down
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10
Q

Causes and risk factors of TBI

A

Due to transportation accidents:
People under 75 get TBI more through the accident
People above 75 ,the brain shrinks causing more space in the skull. When they fall down or there’s a trauma that’ll cause the brain to shake violently,the vessels tear and blood fluid leaks into the epidural space causing epidural hematoma
Violence can cause TBI
Sports injuries
Alcohol use

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11
Q

How will an old TBI patient present
What are the signs of TBI(mild,moderate,severe)

Small children with moderate to severe TBI may show some of these signs as well as signs specific to young children, such as persistent crying, inability to be consoled, and/or refusal to nurse or eat
True or false

A

Old person falls down,gets confused or disoriented,becomes fine,collapses after he or she is fine

Mild -Consciousness +(-)
–Feel dazed or not like himself for days or weeks
–Headache
–Confusion
–Lightheadedness
–Dizziness
–blurred vision or tired eyes
ringing in the ears
•bad taste in the mouth
•fatigue or lethargy
•a change in sleep patterns
•behavioral or mood changes
•trouble with memory, concentration, attention, or thinking

moderate-Moderate/Severe: symptoms of mild plus
–headache that gets worse or does not go away
–repeated vomiting or nausea
–convulsions or seizures
–inability to awaken from sleep
–dilation of one or both pupils of the eyes

slurred speech
–weakness or numbness in the extremities
–loss of coordination and/or increased confusion, restlessness or agitation

severe symptoms

Especially injury due to swelling takes time to show so detain patient to observe cuz the signs will show or discharge and educate patient about the danger signs so he rushes to the hospital when the sign is seen

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12
Q

Name the signs seen when the seizure affects the different parts of the brain

A

Symptoms depends on which part of the brain is affected
•Temporal lobe seizures
–Epigastric discomfort, déjà vu, a smell or taste
•Frontal lobe seizures
–Head turning, jerking of a limb or speech arrest.
•Parietal lobe seizures
–Lateralized sensory symptoms e.g. pain or tingling
•Occipital lobe seizures
–Elementary visual hallucinations (colours and shapes) in the contralateral visual field

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13
Q

Name six ddx for epilepsy and two complications

A

Syncope (eg, cardiac arrhythmia, vasovagal syncope)
•Metabolic conditions (eg, hypoglycemia)
•Migraine (eg, migrainous aura, migraine equivalent)
•Vascular conditions (eg, transient ischemic attacks, stroke)
•Sleep disorder (eg, cataplexy, narcolepsy, night terror)

Movement disorder (eg, paroxysmal dyskinesia)
•GI conditions (eg, esophageal reflux in neonates and infants)
•Psychiatric conditions (eg, conversion, panic attacks, breath-holding
spells,malingering)

COMPLICATIONS
•Status Epilepticus
–More than 30 minutes of continuous seizure activity or two or more sequential seizures without full recovery of consciousness between seizures
•Social
–Social handicap and exclusion
–Educational underachievement
 Unemployment
–Inabililty to drive
–Parents may have to delegate care
–Stigmatization
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14
Q

What are the types of TBI

When do they occur

A

Concussion
–most minor and the most common type of TBI
–is a short loss of consciousness in response to a head injury
•Contusion
–A contusion is a distinct area of swollen brain tissue mixed with blood released from broken blood vessels

A contusion can also occur in response to shaking of the brain back and forth within the confines of the skull ( look up contrecoup)
–Skull fractures
–Hematomas: 3 types
•Epidural
•Subdural
•Intracerebral
–Anoxia
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15
Q

How do you diagnose TBI:

A

History
–should be self-evident
–consider trauma with intracerebral pathology in any patient with a coma of unknown etiology
–An eyewitness account may be crucial especially in the initial confused states
•Examination should include
–Thorough neurological exam including cranial nerves
–Glasgow coma score: mainstay of rapid neurologic assessment in acute head injury

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16
Q

What are the investigations for TBI

A

Imaging
–CT Scan:
•main imaging modality used in the acute setting
•In general, patients with any loss of consciousness should undergo CT scanning
•Repeat CT is needed when clinical deterioration occurs
–MRI:
•reserved for patients who have mental status abnormalities unexplained by CT scan findings
•demonstrated to be more sensitive than CT scanning, particularly at identifying nonhemorrhagic diffuse axonal injury lesions
–EEG: Limited use

17
Q

State some complications of TBI

A
Posttraumatic psychiatric disorders
–Disorders of emotional functioning
•Depression
•Bipolar Disorders
–Impulsive and disinhibited behaviors especially in frontal lobe injuries including OCD
–Head injury-related psychosis
•Posttraumatic movement disorders
–Tremor, dystonia, parkinsonism, myoclonus, and hemiballism

Posttraumatic headaches
–common and may occur in 30-90% of patients after a head injury
•Posttraumatic Epilepsy
–occur clinically in approximately 4% of patients with head injuries within the first week of the injury
–Continuous EEG monitoring has disclosed a higher incidence (22%).

18
Q

How do you manage a TBI patient

A

Call for help(emergency team and tray): to give instructions to what they should do example if you’re checking A,person checks B,someone else checks C
ABCDE assessment
A- ask patients name and call patients name. If patient can’t respond,check nose,pharynx,oropharynx if something is blocking it
If you see something,suction it
B- Check if the chest rises and falls : check the nostrils to see if breath can be felt. Give intra nasal oxygen at 6L/m if person isn’t breathing properly and after you’ve identified if it’s a breathing problem or a ventilation problem
C- Secure line,check pulse , capillary refill,take sample, start volume expanders or crystalloids( fluids such as ringers and normal saline. NB that you should choose NS over RL cuz NS is first line in this situation)

19
Q

Case scenario
25yo involved in a TBI
Vitals-90/60mmhg,86% -SPO2, pulse -125bpm ,sensarium-semiconscious,temp-35degrees
How will you assess this patient
What is preload and after load
How do you know if you’re overloading a patient w fluids
Give some scans done for TBI patients and their uses
What drug can you give to TBI
What’s the function of Mannitol in TBI patients
What are the signs of raised ICP

A

Make sure you’re safe
Shout for help
A- call patients name to check if airway patent. Put on neck collar to stabilize c spine
B- patients SPO2 (oxygen delivered to tissues)is low so move to a higher oxygen delivery device and recheck it after some time
C- pulse rate is high,bp is low so patient has hypotension. These are signs of bleeding or shock . Bleeding causes this cuz there is impaired venous volume and the brain reacts by triggering the sympathetic. Sympathetic stimulates SA node and there’s firing of more action potential causing the heart to beat faster causing the high pulse and increased cardiac output while stroke volume is reducing. After sometime When stroke volume is too low,no matter how much the body compensates by making the heart beat faster , cardiac output won’t increase causing the bp to be low
Preload is the blood going to the heart and afterload is Starlings mechanism.
If you’re giving fluids to increase the stroke volume thereby increasing cardiac output and bp and pulse are still the way it is then add more fluids. After sometime begin listening to the base of the lungs for crepitations and if you hear any then it means you’re overloading the patient
Take a quick and brief history and expose patient
E- do head to toe exam ( examine head,neck- suspect spinal injury if you palpate the neck and it’s tender, laguna sign occurs when chemosis forms around the orbit of the eye. This shows the base of the skull is fractured. This means w little pressure exerted ,the brain in the skull will push through the foramen magnum )
C- do log roll (three people one holding head,one holding trunk,one holding legs)
Now that all the vitals are normal after stabilizing patient then send patient for scans to find internal injuries (skull X ray to check for fracture or bleeding and CT scan shows if there’s injury to the brain. If there’s Brian injury give mannitol which is a hyperosmolar fluid to draw fluid from cells to plasma to reduce the ICP. Cervical and thoracic vertebrae X rays, lumbar sacral X-ray,total body X ray ,abdominal scan
Put patient on monitoring chart (seizure,temperature,other vitals,monitor consciousness or unconsciousness)or cardiac monitor cuz the brain injury can cause seizures and disrupt the temperature to cause hypothermia
After doing all you can,refer

You can give corticosteroids to reduce the inflammation which will cause the ICP cuz they’re immunosuppressants

Headache.
Blurred vision.
Feeling less alert than usual.
Nausea
Confusion
Vomiting.
Changes in your behavior.(aggression and restlessness)
Weakness or problems with moving or talking.
Lack of energy or sleepiness.
Increase respiratory effort