A&P Final Flashcards
Units 1-4,6, and unit 7 & 8 ; adding unit 5 right now
Integumentary sx
Contains the skin, hair & nails; offers protection, temperature regulation, water retention & sensation of the body
Skeletal sx
Contains the bones, cartilage & ligaments; offers protection to the body organs, support & movement with muscles & contraction as well as blood formation through blood marrow
Muscular sx
Contains primarily skeletal muscles; offers movement through muscle contraction & skeletal/heart muscles, assists with posture & heat production
Lymphatic system
Contains lymph nodes, lymphatic vessels, lymph, thymus, spleen & tonsils; sx has role in fluid balance, production of immune cells & defense against disease
Respiratory sx
contains nose, pharynx, larynx, trachea, bronchi & lungs; sx absorbs oxygen, discharges carbon dioxide, acid base balance & assists with speech
Urinary sx
contains kidneys, ureters, urinary bladder and urethra; sx assists with excretion of wastes, regulation of blood volume & pressure, control of fluid & electrolytes and acid based balance
Nervous sx
Contains brain, spinal cord & sense organs; sx controls, regulates & coordinates the other sxs, also assists with sensation & memory
Endocrine sx
contains pituitary gland, adrenals, pancreas thyroid, parathyroids & other organs; sx assists with hormone production & control/regulation of other sx
Circulatory sx
contains the heart, arteries, veins & capillaries; sx has a distribution of oxygen, nutrients, waste hormones, immune cells, electrolytes & antibodies. Also does fluid, electrolyte & acid-base balance
Digestive sx
contains stomach, small & large intestines, esophagus, liver, mouth & pancreas; sx breaks down and absorbs nutrients as well as eliminates waste
Male reproductive sx
contains testes, vas deferens, prostate, seminal vesicles & penis; sx does things for body such as secretion of sex hormones & production/delivery of sperm
female reproductive sx
contains ovaries, fallopian tubes, uterus, vagina & breast; sx produces eggs, site of fertilization & fetal development, birth, lactation & secretion of sex hormones
Epithelial tissues
covers or lines body surfaces such as the outer layer of skin, walls of capillaries & kidney tubules
Connective tissue
connects & supports parts of the body, transports & stores materials. Some examples are bone, cartilages & adipose tissues
Muscle tissue
contracts to produce movement such as skeletal & heart muscles
Nerve tissue
generates & transmits impulses to regulate body functions such as the brain & nerves
Sagittal plane
divides into left and right sides however they are not equal sides
Midsagittal plane
divides into left and right sides equally
Transverse plane
divides the body into upper and lower portions can be also called the horizontal plane
Frontal plane
divides the body into anterior and posterior portions, can also be called coronal place since the line crosses the crown of the head
Describe anatomical position
Used to identify locations of body parts, accurate communication. Anatomical position is standing straight up with arms at side with face, palms and feet facing forward
Dorsal body cavity
Located along the posterior side of the body(back); contains cranial cavity which holds the brain and spinal cavity which holds the spinal cord
Ventral Body cavity
Along the anterior side of the body (front); contains the thoracic cavity which is above the diaphragm contains the lungs, heart & mediastinum & also contains the abdominopelvic cavity which divides into abdominal cavity (under the diaphragm, above the pelvis & contains the stomach, liver, gall bladder, pancreas, spleen, small intestine, most of the large intestine & kidneys) also the pelvic cavity which contains the urinary bladder, rectum & internal reproductive organs
9 abdominal regions
right & left hypochondriac region, right & left lumbar region, right & left iliac region, epigastic region, umbilical region, hypogastic region
4 quadrants
RUQ, RLQ, LUQ, LLQ
Abdominal pain; where is the appendix located
right lower quadrant; located in right iliac region & tip of appendix in right lumbar region
abdominal pain; where is the gallbladder located
right upper quadrant , can also can referred pain in the shoulder; gallbladder located in right hypochondriac region
What elements make up 96% of human body?
CHON- Carbon, Hydrogen, Oxygen & Nitrogen
What element makes up the greatest % of body weight?
Oxygen makes up 65% of body mass
Electrons
carry a negative charge; move around the nucleus in concentric clouds that represent different energy levels
Protons
carry a positive charge which is contained in the nucleus. Differentiate one element from another
Neutrons
electrically neutral
Define isotopes
an atom of an element containing a different number of neutrons
define covalent bonds
formed when atoms share one or more pairs of electrons; stronger than ionic bonds, used to create many of the chemical structures of the body
Define metabolism
the sum of all chemical reactions in the body
Catabolism
breaks down complex compounds into simpler ones, releases energy some heat mostly transferred into ATP
Define Anabolism
Larger, more complex chemical molecules from smaller subunits require energy; obtains energy from atp
chemical reactions: synthesis
A + B → AB ; Two or more substances combine to form a different more complex substance, new bonds are formed and energy is required. Ex wound healing; fors collagen to repair skin
Chemical reaction: decomposition
AB → A + B; A complex substance breaks down into two or more impeller substances; bonds are broken; energy is released- this energy can be released in the form of heat or stored for future use
Chemical reaction: Exchange
AB + CD → AC + BD
Two molecules exchange atoms or groups of atoms, which form two new compounds
define compound
two or more elements combine to create a new substance, new substance has its own chemical properties
define mixture
two substances blend together, do not chemically combine. Each retains unique chemical properties
define solution mixture
mixture is particles of matter (solute) dissolved in a substance (solvent). Can be gas, solid or liquid and also must be clear
Define colloid
mixture of protein and water, can change from liquid to gel and particles are small enough to stay mixed. Mixture is cloudy
Define suspension
contains large particles, will look cloudy or opaque, particles will settle
Importance of water & characteristics
water is a solvent, lubricant & water changes temperature slowly.
define pH scale
The acidity or alkalinity of a substance is expressed in terms of pH, pH scale ranges from 0-14
pH of blood
7.35-7.45
pH ranges
Acidic- solution with a pH less than 7
Alkaline- solution with pH of 7 is neutral
Neutral- solution with pH greater than 7
Organic compound 1 of 4
Carbohydrates- group of organic compounds known as starches or sugars that serves as the bodys primary source of energy
Organic compound 2 of 4
lipids- group of fats characterized by their insolubility in water
Organic compound 3 of 4
Proteins- very large molecules consisting of smaller chemical subunits called amino acids
Organic compound 4 of 4
Nucleic acids- complex organic substances especially in DNA & RNA
Define & specific task of Nucleolus
manufactures ribosomes
Define & specific task of endoplasmic reticulum
network of membranous canals & curving sacs through out the cytoplasm
Define & specific task of ribosomes
manufacture proteins; dot the surface of some of the ER
Define & specific task of microvili
folds of the cell membrane; increases the surface area of the cell
Define & specific task of cilia
hair like processes on the cell surface; moves in waves to propel a substance forwards
Define & specific task of flagella
uses a whip like motion to move a cell
define hydrostatic pressure
as water diffuses by osmosis into a solution, the volume of that solution increases, exerting more pressure
define osmotic pressure
water pressure that develops in a solution as a result of osmosis
define hypotonic
A solution with a lower concentration of solutes when compared to that inside the cell; water moves by osmosis into the cell; influx of water causes the cell to swell & burst (lysis)
Define hypertonic
A solution with a higher concentration of solutes than the concentration of the cell (inside the cell); water moves out of cell; cell shrivels & may die3% Normal saline (3% NaC)
define isotonic
A solution with the same concentration of solutes as that inside the cell; water moves into & out of the cell at an equal rate; cells remain normal in size
Sodium potassium pump
Active transport, Regulates the volume of fluid within cells, Provides the electrical potential necessary for nervous system activity, Helps in heat production, Transfers sodium from inside the cell (where sodium levels are low) to outside the cell (where sodium levels are higher), At the same time, it transfers potassium from the extracellular fluid (where potassium levels are low) to the cell’s interior (where potassium levels are higher)
Define human microbiome
essential for human life
Define human microbiome project
scientist are doing DNA sequencing research to identify bacteria in our body; unseen world & bacteria cells out number human cells
define bacteria
tiny, single celled organisms that are a major part of the microbiome
define capsule
a jelly like layer that keeps bacteria moist and protects them
define viruses
extremely small infectious agents, not cells, to reproduce they must be inside a host cell, viruses are simply a bundle of genetic material (RNA or DNA) surrounded by a protein shell called a capsid
Define fungi
common & easily spread, many fungal infections start on skin or lungs, lives in soil, plants and in the air. million of fungal species are part of the human microbiome
define pathogen
a microogranism know to cause disease; invasion by disease causing bacteria
define archaea
microscopic single cels organisms that like bacteria, do not contain a nucleus, lacks peptidoglycans. 3 domains make up life on earth; bacteria, archaea and complex life
what is the link between bacteria & antibiotic resistance
plasmids are small loops of DNA inside bacteria that can be shared with other bacteria, helping them quickly adapt to changes.
Gram-positive bacteria & how antibiotics work
have a thick later of peptidoglycan in cell wall, retain dye, stains purple; Antibiotics such as penicillin work by attacking the peptidoglycan in the bacterial cell wall, they are more effective against Gram-positive bacteria
Gram-negative bacteria & how antibiotics work
thin layer of peptidoglycan in cell wall & also have outer membrane, lose dye when rinsed and appears red or pink ;Gram-negative bacteria are often more resistant to antibiotics due to their outer membrane, which blocks many drugs, and mechanisms like efflux pumps and beta-lactamase enzymes that destroy or expel antibiotics.
general understanding of the fertilized egg & role in tissue development
A fertilized egg organizes into three layers; each of these layers gives rise to a different type of tissue (EndodermMesodermEctoderm) Layers continue to divide; eventually each layer gives rise to a different type of tissue differentiation, Stem cells can differentiate into many different types of cells
Ectoderm (outer layer)
gives rise to epidermis and nervous system
mesoderm (middle layer)
gives rise to connective & muscle tissue ( cardiac muscle, skeletal muscle, bone, blood & smooth muscle)
Endoderm (inner layer)
produces mucous membrane of respiratory tract, thyroid gland, secretory parts of pancreas
define differentiation
the process of each layer gives rise to a different type of tissue
Epithelial tissue
epithelial tissue is a continuous sheet of tightly packed cells; it covers the body’s surface, lines body cavities and many organs, and forms certain glands. Key functions involve protection, absorption, filtration, and secretion.
Connective tissue
Existing in a variety of forms—ranging from tough cords to elastic sheets to fluid—connective tissue performs a variety of tasks. The overriding purposes of this seemingly diverse group of tissues are to connect the body together and to support, bind, or protect organs.
Nervous tissue
Nervous tissue has a high degree of excitability and conductivity, It’s these characteristics that allow it to communicate rapidly with other parts of the body, Nervous tissue has a high degree of excitability and conductivity—more so than other tissues. It’s these characteristics that allow it to communicate rapidly with other parts of the body.
Muscle tissue
Muscle tissue consists of elongated cells that contract in response to stimulation. The body contains three types of muscle tissue: skeletal, cardiac, and smooth.
components of connective tissue
extracellular matrix, The matrix consists of varying kinds and amounts of protein fibers and fluid; it’s the variation in composition that gives tissue its characteristics;
*Collagenous fibers: These are strong and flexible but resist stretching; these are the most abundant fibers.
* Reticular fibers: These occur in networks and support small structures such as capillaries and nerve fibers.
* Elastic fibers: Made of a protein called elastin, these fibers can stretch and recoil like a rubber band.
Define stem cells
specialized cells that can differentiate into many different type of cells
Define exocrine glands
secrete products into ducts; the ducts then empty onto a body surface or inside a body cavity, ex gastic juices, tears & swear
define endocrine glands
secretes hormones directly into the blood; known as ductless glands; ex ovaries, pitutiary gland
key functions of epithelium
fxn in protection, absorption, filtration & secretion, covers body surfaces, lines cavities & organs, forms glands
define goblet cells
modified cells containing secretory vesicles that produce large quanitites of mucus ex epithelial lining of organs; the intestines & respiratory tract
connective tissue
most widespread & diverse, exists in a variety of forms, fxn & purpose is to connect the body together & support, bind, or protect organs
extracellular matrix
consists of protein fibers & fluid, framework in which cells are embedded
Basic types of connective tissue: connective tissue
Loose Connective Tissue: Includes areolar, adipose, and reticular tissue. It provides cushioning, insulation, and support for organs.
Dense Connective Tissue: Includes dense regular, dense irregular, and elastic tissue. It forms strong structures like tendons and ligaments.
Basic connective tissue: cartilage
Types: Hyaline, elastic, and fibrocartilage.
Provides flexible support and reduces friction in joints.
Basic connective tissue: Bone
Made of compact and spongy bone.
Provides structure, support, and protection for the body.
Basic connective tissue: Blood
A fluid connective tissue composed of cells (red blood cells, white blood cells, platelets) suspended in plasma.
Transports nutrients, oxygen, and waste.
Basic connective tissue: Lymph
Fluid connective tissue that helps with immune responses and the return of interstitial fluid to the bloodstream.
Skeletal muscle
Long, cylindrical, multinucleated fibers with a striated (striped) appearance. It is under voluntary control, meaning movements can be consciously controlled.
Location: Attached to bones by tendons; found in muscles like the biceps, quadriceps, and diaphragm.
Function: Enables movement of the skeleton, posture maintenance, and heat production.
Cardiac muscle
Branched, striated fibers with a single nucleus per cell and intercalated discs that allow for synchronized contractions. It is under involuntary control.
Location: Found exclusively in the walls of the heart (myocardium).
Function: Pumps blood throughout the body by rhythmic contractions.`
Smooth muscle
Spindle-shaped, non-striated cells with a single nucleus. It is under involuntary control.
Location: Found in the walls of hollow organs such as the stomach, intestines, blood vessels, bladder, and uterus.
Function: Facilitates movement of substances through the organ (e.g., food in the digestive tract or blood through vessels) and regulates internal processes like blood pressure.
Tissue repair: regeneration
damaged tissue cells are replaced with the same type of cells, resulting in functional new tissue
tissue repair: Fibrosis
damaged tissue is replaced with scar tissue (which is mostly collagen); fibrosis does not restore normal function
Granulation tissue
newly formed tissue; fibroblasts in the granulation tissue secrete collagen, which forms scar tissue inside the wound*White blood cells ingest bacteria & cellular debris to keep the wound bed clean
Mucous membrane
line body surfaces that open directly to the body’s exterior; secrete mucus, which protects cells of the membrane, acts as a lubricant to propel food through the digestive tract & traps dust and bacteria in the respiratory tract. The type of epithelium varies according to location and functio
Cutaneous membrane
(or skin) is the body’s largest membrane; consists of a layer of epithelium on a layer of connective tissue`
Serous membrane
consists of simple squamous epithelium on a thin layer of areolar connective tissue. The portion covering the wall of the cavity is the parietal membrane, which folds back & covers the organs; this is the visceral membrane;which secretes serous fluid, which reduces friction as organs expand & contract
Pleura membrane
serous membrane; surrounds each lung and lines the thoracic cavity
Pericardium
serous membrane; surrounds the heart
peritoneum
lines the abdominal cavity and covers the abdominal organs
serous fluid
helps prevent friction as the heart beats & lungs expand
what functions & roles does the skin play as it relates to the human body?
protection & temperature regulation
define melanin
produced by melanocytes, determines a persons skin color by the amount & type of melanin (NOT THE # OF MELANOCYTES)
Define albinism
a genetic lack of melanin, extremely pale skins, white hair & pink eyes
define keratin
a tough, fibrous protein
Clubbing
Abnormal nail change, long term oxygen deficiency usually a result of lung disease
Cyanosis
a deficiency of oxygen in circulating blood, ex blood tint on the tip of fingertips when cold
pale nail beds
decreased blood flow, such as cold temps, fears or emotional stress, low blood pressure
yellowish thickened nails
impaired liver functions, allows bile to accumulate which stains
Describe the changes in the skin due to aging process & how it affects body temperature regulation
Thinning of the Epidermis and Dermis- The skin becomes thinner and less resilient due to reduced cell production and collagen breakdown.
Decreased Elasticity- Loss of elastin fibers leads to sagging and wrinkling of the skin.
Reduction in Sweat Glands and Sebaceous Gland Activity- Fewer active sweat glands reduce sweat production, while decreased oil secretion makes the skin drier.
Decline in Blood Flow- Reduced blood supply to the dermis affects nutrient delivery and temperature regulation.
Loss of Subcutaneous Fat- Thinning of the subcutaneous layer reduces insulation, making the skin more sensitive to temperature changes.
Impact on Body Temperature Regulation
Impaired Sweating
what is insensible perspiration: define & describe
insensible perspiration: perspiration that doesn’t make the skin feel damp. Perspiration increases dramatically from heat or exercise. In fact, the body can lose as much as a liter of perspiration an hour from intense exercise or extreme heat. If the fluid isn’t replaced, dehydration or even circulatory shock may result.
eccrine glands
contain a duct that leads from the secretory portion to the skin’s surface. Eccrine glands produce sweat; which plays a role in helping the body maintain a constant core temperature & helps the body eliminate wastes
apocrine glands (sweat glands)
contain a duct that leads to a hair follicle; respond to stress & sexual stimulation. *Sweat produced by apocrine glands does not have a strong odor when it accumulates on the skin, bacteria begins to degrade substances in the sweat, resulting in body odor
Sebaceous glands
Secrete an oily substance called sebum; helps keep the skin & hair from drying out and becoming brittle*Has a mild antibacterial & antifungal effect
ceruminous glands
Exist in the external ear canal; secrete a waxy substance called cerumen (ear wax); helps keep ear canal from drying out*Excess cerumen can accumulate in the ear canal & harden, diminishing hearing
First degree burn
only involves the epidermis, causes redness, slight swelling & pain, can result from sunlight (AKA sunburn), burns is risk for infection, black scab holds bacteria in & restricts blood flow, a partial thickness burn
second degree burn
involves the epidermis & part of the dermis; results in blisters, severe pain & swelling, may result in scarring, can appear red, white or tan & a partial thickness burn
third degree burn
extends through epidermis & dermis & into the subcutaneous layer, full thickness burn. May not be painful initially (nerve endings are destroyed), often requires skin grafts, risk for infection, fluid loss & lack of thermoregulation
rules of nines
divides the body into areas of 9%, add corresponding percentages for each body section burned
Long bones
longer than they are wide, work like levers to move limbs
short bones
shaped like cubes
flat bones
thin, flat, often curved bones, they protect organs and other flat bones (ex scapulae) provide large surface area for the attachment of mucles
irregular bones
often clustered in groups, comes in various sizes & shapes
sesamoid bones
small bones imbedded in tendons
Parts of long bone: diaphysis
Hollow cylinder, compact bone; gives bone strength to support the body weights
parts of long bone: articular cartilage
hyaline membrane; covers the epiphysis(head of each end of a bone) eases movement of the bone within a joint
parts of a long bone; medullary cavity
central hollow portion of the diaphysis; filled with yellow bone marrow
parts of a long bone; endosteum
epithelial membrane lining the medullary cavity
parts of a long bone; red bone marrow
fills the medullary cavity in children; in adults most marrow has turned yellow
Parts of a long bone; periosteum
A dense, fibrous membrane covering the diaphysis; some penetrate the bone & other fibers weave together with the fibers of tendons to ensure a strong connection between muscle and bone; *Contains bone-forming cells & blood vessels; crucial for bone survival
parts of a long bone; epiphyseal plate(growth plate)
The layer of cartilage separating the epiphysis from the diaphysis at the ends of a long bone in growing children. When growth stops, it is replaced with an epiphyseal line
parts of a long bone; Osteomyelitis
an inflammation of bone and marrow, usually the result of a bacterial infection. Bone infections are often difficult to treat and typically require prolonged intravenous antibiotic
osteoblasts
Help form bone by secreting substances that makeup bone matrix
osteoclasts
Dissolve unwanted bone or unhealthy bone tissue
Osteocytes
Are mature osteoblasts embedded in hardened bone matrix; some dissolve bone, whereas others deposit bone- contributing to the maintenance of bone density; helps regulate blood levels of calcium & phosphorus‒Become more active when building bone
torsional strength
bone can not endure much twisting
compressional strength/calcium salts
allows bones to resist strong squeezing forces
tensile strength/collagen fibers
in the matrix make bone highly resistant to stretching forces
compact bone
forms shafts of long bones & surfaces of other bones; dense & solid; offers strength
spongy bone
found in the ends of long bones and middle of other bones, always surrounded by compact bone
ossification; new bone development
this early skeleton evolves into bone, two types of ossification processes: one for fibrous connective tissue & one for cartilage
Intramembranous ossification: new bone development
Begins in a fibrous connective tissue membrane.
Mesenchymal cells differentiate into osteoblasts, which secrete bone matrix.
The matrix calcifies, trapping osteoblasts, which then become osteocytes.
Trabeculae form, creating spongy bone, and the outer layers may compact to form compact bone.
Endochondral ossification; new bone development
Begins in a cartilage model made of hyaline cartilage.
Chondrocytes (cartilage cells) enlarge, die, and are replaced by bone tissue.
Blood vessels invade the area, bringing osteoblasts that form bone matrix.
Bone development proceeds from the primary ossification center in the diaphysis (shaft) and extends toward the epiphyses (ends).
Secondary ossification centers form in the epiphyses, leaving cartilage only at the growth plates and articular surfaces.
Define trabeculae
Spongy ( cancellous bone) consists of a latticework of bone , are arranged in a way that offers maximum strength. If the stress a bone is exposed to changes, the trabeculae will realign to compensate
osteon
the basic structural unit of compact bone
lacunae
tiny gaps between rings of the lamellae
lamellae
layers of matrix are arranged in concentric rings
volkmanns canals
transverse passageways, connect the haversian canals; they transport blood & nutrients from the bone’s exterior to the osteocytes locked inside
bone formation at 2 years of age
skull is completely ossified
bone formation in utero
fetus skeleton composed of mostly cartilage
bone formation at 3 months of age
cartilage beings to turn into bone
simple fracture
remains aligned & tissue intactscom
compound fracture
bone breaks skin; damage to nerve & blood vessles; high risk for infection
greenstick fracture
an incomplete break
comminuted fracture
bone break due to high impact trauma, broken into pieces (ex motor vehicle )
spiral fracture
spiraling fracture, bone twisting, difficult to reposition/align (suspect abuse)
pathologic fracture
fracture due to pathologic condition or cancer
the nucleus of the cell is called the control center because
it contains cells genetic info
the plasma membrane is made up of
phospholipids, cholesterol & protein
chief purpose of the golgi apparatus
prepare and package proteins to export them
function of mitochondria
powerhouse, converts organic compound into atp
define osmotic pressure
osmotic pressure occures when water pressure develops in a solution as a result of osmosis
define passive transport
do not require energy, depend on substance moving down concentration gradient
define diffusion
molecules evenly distributed throughout a given area until substance reaches equilibrium
define osmosis
passive movement of water through selectively permeable membrane
define faciliated diffusion
transport process from small charged or polar solutes requires assistence from plasma through a channel protein
define active transport
requires energy; movement of solute against its concentration gradient
how many adult bones in the body
206 bones
Axial skeleton
Central, supporting axis- skull, vertebral column, and rib cage
Appendicular skeleton
bones of the limbs, pelvic & shoulder areas; relates to the appendages of the body such as arms & legs
Coronal suture
between parietal & front bone
sagittal suture
between right & left parietal bones
squamous suture
edge of temporal bone
lambdoid suture
between parietal & occipital bone
Newborn bone count
300 bones or more
Infant skull; suture lines
suture lines in the skull have not fused yet, also for infants to pass through birth canal also allows for rapid brain growth during infancy
infant skull fontanels
areas between unfused bones covered by fibrous membranes called fontanels, soft to touch, by the age two fontanels are closed
s & s assosciated with abnormal findings in infant skull
-wide suture lines suggest hydrocephalus(excessive amounts of cerebrospinal fluid)
-sunken frontanel suggest dehydration
-bulging frontanel suggest intracranial pressure
five sections of the vertebral column
cervical (7) , thoracic (12) , lumbar(5), sacrum (5) & coccyx (4 fused)
define scoliosis
lateral curvature of spine
define kyphosis
thoracic curvature “hunchback”
define lordosis
Lumbar curvature “Swayback”n
vertebrae characteristics:vertebral foramen
allows passage of spinal cord
vertebrae characteristics: body
weight bearing portion of the vertebra
vertebrae characteristics: spinous process
projects posteriorly from the vertebra, the bumps you feel along the spine