A&P Flashcards

1
Q

How many thorax vertebrae are there?

A

12

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2
Q

What two types of neurons are multipolar?

A

Interneurons

Motor Neurons

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3
Q

Nerves that synapse in a distal collateral ganglion anterior to the vertebral column or close to the effector organ are typically ____________?

A

Parasympathetic

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4
Q

Volume of the cranium?

A

1200–1500ml

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5
Q

Why is the gray matter enlarged in C3–C5 and L3–L5?

A

To accommodate for brachial plexus and sacral.

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6
Q

True or false: Ach is the preganglionic for the SNS and the PSNS

A

TRUE

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7
Q

Broca’s is for ___________.

Wernicke’s is for _________.

A
Broca= speech production.
Wenicke's = Understand speech
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8
Q

Aside from the arachniod villi, _______ channels absorb CSF.

A

Lymphatic

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9
Q

For a brief time during depolarization, the inside of the membrane potential becomes how high?

A

30

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10
Q

CBF is greatly increase when PaO2 is less than __________.

A

50

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11
Q

True or False: Epidural catheters are threaded into the subdural space.

A

FALSE

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12
Q

Pain fibers travel through the dorsal roots and synapse with ________ order neurons in the ____matter of the spinal cord

A

2nd

gray

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13
Q

The area just in front of the primary motor cortex (precentral gyrus)?

A

Somatic Motor Association Area (premotor cortex)

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14
Q

What are internuncial neurons?

A

Interneurons

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15
Q

When MAP/CPP increase above autoregulation threshold, what happens to cerebral vasculature

A

Vasoconstriction (to try to decrease CBF)

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16
Q

The globus pallidus, putamen and caudate make up the corpus striata. These are within what part of the brain?

A

Basal Ganglia

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17
Q

Projection of a astrocyte?

A

Astrocytic feet

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18
Q

________ SNS nerve exitsthe ventral horn and white rami.

A

White Matter

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19
Q

CBF is autoregulated between a MAP of ________

A

60–160

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20
Q

Sensory pathways of the head and face form the trigeminal nerve and ascend to the ventral posteromedial nucleus of the _________

A

Thalamus

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21
Q

What structure contains many fibers that connect 2–3 hemispheres together with neurons that arise in one hemisphere and synapse in another?

A

Corpus Callosum

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22
Q

SNS presynaptic nerves all leave the spinal cord via the _________ horn.

A

Intermediolateral

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23
Q

What can the brain uptake and metabolize for energy when lacking glucose? This is very rare

A

Lactate

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24
Q

True or False: Ions and Ionized substances easily cross the BBB.

A

FALSE

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25
Q

________ junctions between endothelial cells prevent ionized, large, non–lipid soluble subs from crossing the BBB

A

Tight

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26
Q

Inhibitory NTM within the hypothalamus and RAS

A

Histamine

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27
Q

Master neuro–hormonal–endocrine organ?

A

Hypothalamus

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28
Q

The termination of the spinal cord?

A

Conus Medullaris

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29
Q

8% of cranium is ______

A

CSF

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30
Q

Temperature and Pain (A delta and C fibers) = ____________ spinothalamic tract

A

Lateral

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31
Q

CBF averages _______ml/minute in adults

A

750

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32
Q

Oligodendrocytes are ___________ of regrowth if they are destroyed.

A

NOT CAPABLE

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33
Q

The vertebral arteries come from the _______ artery.

A

Subclavian

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34
Q

The axon is negatively charged at rest due to negatively charged ______ inside and because ______ is constantly leaking out of the membrane.

A

Proteins

Potassium

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35
Q

Pain fibers release this excitatory NT to synapse with the substantia gelatinosa

A

Substance P

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36
Q

The ______ matter is composed of myelinated axons.

A

White Matter

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37
Q

The NT at CN nuclei, ventral horn motor nerves, and various interneurons?

A

Ach

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38
Q

Note the pseudo–unipolar cell body is along the ______. This area is known as the ________________.

A

Axon

Dorsal Root Ganglion

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39
Q

Occipital lobe is primarily for ________

A

Vision

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40
Q

Crude touch and pressure = __________ spinothalamic tract

A

Anterior

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41
Q

Rexed lamina 1–6 occur in the _______ gray matter ______ horn.

A

Dorsal

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42
Q

What is rexed laminae 2 (or 3 in some texts)?

A

Substantia Gelatinosa

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43
Q

A–Alpha diameter and conduction velocity?

A

10–20micrometer

70–120m/s

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44
Q

The SNS postganglionic neuron breaks it’s own rule and releases acetylcholine at what location in the body?

A

Sweat Glands

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45
Q

The CSF leaves the cistern magna and enters the ________ space to circulate the CNS before absorption.

A

Subarachnoid

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46
Q

The ______ is also referred to as the primary motor cortex.

A

Prefrontal Gyrus

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47
Q

Collections of sensory nerve fibers near the spinal cord?

A

Dorsal Root Ganglion

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48
Q

When viewing the Homonculus, where is the hand, fingers, thumb, neck, brows, and eye?

A

Middle

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49
Q

What type of neurons make up the somatic and autonomic nervous system?

A

Motor Neurons

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50
Q

What two arteries in the circle of willis are unpaired?

A

Basilar

Anterior Communicating

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51
Q

Which vertebrae are fused?

A

Sacral Coccygeal

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52
Q

What do 2nd order neurons synapse with in the ventral posterolateral thalamic nucleus?

A

3rd order neurons

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53
Q

12% of cranium is _________

A

Blood

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54
Q

Functional unit of neuron

A

Axon

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55
Q

Major pathway of ascending and descending nerves from the homunculus to the midbrain?

A

Internal Capsule

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56
Q

What does a bipolar neuron look like?

A

Dendrite – Cell body – Axon terminal

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57
Q

How many interneurons are involved with the A–delta pathway

A

None

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58
Q

This thin, avascular layer is just below the dural and subdural layer?

A

Arachnoid

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59
Q

Where does the edinger–westphal nucleus come from?

A

The occulomotor nerve

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60
Q

What is the large cranial nerve that exits the Pons in Laffoon’s brainstem pic?

A

Trigeminal

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61
Q

When pain and temperature neurons synapse with motor neurons in the ventral horn it creates a…?

A

Reflex Arcs

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62
Q

CSF is formed and secreted by specialized ______ cells in the __________ at a rate of ________ per hour.

A

Ependymal

Choroid Plexus

20–30

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63
Q

The area just behind the primary sensory cortex?

A

Somatic sensory association area

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64
Q

This type of neuron has a cell body, dendrites are on the axon, and axon terminals are at the other end?

A

Unipolar. Not in humans

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65
Q

This cranial nerve is responsible for movement of the neck and shoulder?

A

Accessory

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66
Q

Most of CMRO2 is to create ________ for neuronal activity.

A

ATP

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67
Q

The fasciculus gracilis is more ______ than the fasciculus cunateus.

A

Medial

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68
Q

CMRO2 changes _________% for every 1 degree change in body temperature.

A

7%

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69
Q

This section of the brainstem is continuous with the spinal cord and contains respiratory and cardiac control centers?

A

Medulla (oblongota)

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70
Q

What glial cell plays a role in CSF secretion?

A

Ependymal

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71
Q

_________ lobe is responsible for sensation of touch and limb position.

A

Parietal

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72
Q

What type of glial cell resembeles a dendrite that comes in contact with blood vessels and plays important role in BBB?

A

Astrocyte

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73
Q

Which two cranial nerves provide both motor and sensory information outside of the face?

A

Glossopharyngeal

Vagus

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74
Q

What two things combine to form Ach?

A

Acetyl–CoA

Choline

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75
Q

CBF increases _____% for every 1 degree C increase in temperature

A

5–6%

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76
Q

SNS postganglionic neurons release this NT:

A

NE

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77
Q

What type of glial cell resembles a lipid bilayer?

A

Ependymal cell

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78
Q

True or false: CSF exists in the central canal of the spinal cord.

A

TRUE

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79
Q

What rule says that because the brain is not compressible, any increase in volume results in increased ICP?

A

Monro–Kelly

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80
Q

Where do vibration, discrete touch, and proprioception third order nerves terminate?

A

Postcentral Gyrus (somatosensory area)

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81
Q

What ion restores resting potential during repolarization?

A

Potassium

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82
Q

The ____ division promotes erection and the _______ promotes ejaculation/contraction.

A

PSNS

SNS

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83
Q

90% of motor nerves decussate in the _______ before taking the ___ corticospinal tract.

A

Medulla

Lateral

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84
Q

Sensory nerve fibers have their cell bodies along the ________ of the neuron

A

Axon

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85
Q

What part of the brain consumes the most oxygen

A

Cerebral Cortex

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86
Q

Lumbar–sacral Vibration, discrete touch, and proprioception first order nerves immediately ascend to the medulla via the ____________

A

Fasciculus Gracilis

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87
Q

Lateral and ventral white matter columns are for descending efferent ________ tracts.

A

Motor

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88
Q

The Posterior sulcus, A/P horn, and Lateral horn make up the ______ matter.

A

Gray

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89
Q

The largest cranial nerve?

A

Trigeminal

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90
Q

3 patients who get AA instability?

A

RA
OA
Downs

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91
Q

The abducens nerve is responsible for _____ movmement.

A

eye

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92
Q

How many cervical nerve pairs are there?

A

8

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93
Q

The CSF flow starts in the _________ after the choroid plexus.

A

Lateral Ventricles

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94
Q

How many vertebrae are there?

A

33

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95
Q

How many cervical vertebrae are there?

A

7

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96
Q

PaCO2 of 75mmHg = CBF of ____ ml/100g/min

A

75

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97
Q

75% of patients arteria magna enters on the ____ side.

A

Left

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98
Q

What ion derangement leads to decreased calcium and decreased release of NT?

A

Hypermagnesemia

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99
Q

Thoracic/cervical Vibration, discrete touch, and proprioception first order nerves synapse with second order nerves and, immediately ascend to the medulla via the ____________

A

Fasciculus Cunateus

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100
Q

The gray matter has lots of cell bodies, interneurons, and _______ nerve fibers.

A

Unmyelinated

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101
Q

What anchors the spinal cord to the lower sacral region?

A

Filum Terminale

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102
Q

What is the one exception to the pre/post ganglionic rule?

A

The adrenal medulla is supplied by one preganglionic neuron

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103
Q

The inferior cervical ganglion and 1st thoracic nerve form the ___________.

A

Stellate Ganglion.

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104
Q

Intracranial ______ is determined by measuring the change in ICP in response to changes in intracranial volume.

A

Elastance

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105
Q

What absorbs the CSF?

A

Arachnoid Villi

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106
Q

True or false: Ach is the preganglionic NT for only the PNS

A

FALSE

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107
Q

The _________ neuron terminates on the effector organ.

A

Postganglionic

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108
Q

This section of the brainstem maintains the body’s consciousness, arousal, and alertness?

A

RAS

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109
Q

Spinal nerves originate _____ their vertebrae, besides the cervical

A

Below

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110
Q

The posterolateral fissure separates the posterior lobe of the cerebellum from what lobe?

A

Flocculonodular

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111
Q

Cell membrane of the axon?

A

Axolemma

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112
Q

The exterior layer of the dura is ________ and the internal layer is the __________.

A

Periosteal

Meningeal

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113
Q

Pressure and crude touch can ascend up to ___ levels before synapsing.

A

10 segments

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114
Q

Complex and finer movement areas are from _______ areas of the humunculus.

A

Larger

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115
Q

Cervical nerves originate _______ their vertebrae.

A

Above

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116
Q

How many posterior spinal arteries are there? What percent of blood flow do they provide?

A

2

25%

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117
Q

Another name for the central sulcus

A

Fissure of Rolando

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118
Q

This structure integrates and transmits SENSORY information by connecting the cortex to the rest of the nervous system?

A

Thalamus

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119
Q

True or False: GABA is highly concentrated in the basal ganglia and cerebellum

A

TRUE

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120
Q

The CSF leaves the 4the ventricle through the median aperture (megendie) and also the paired lateral apertures called the foramine of ______.

A

Luschka

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121
Q

3 cranial fossa

A

A/P/Middle

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122
Q

Astrocytic feet that contact blood vessels? What are they important for?

A

Perivascular

BBB

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123
Q

When viewing the Homonculus, where are the legs, knee, hip, and trunk?

A

Medial

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124
Q

What breaks down Ach?

A

Acetylcholinesterase

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125
Q

Water soluble substances cross the BBB ________

A

easily

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126
Q

_________ form myelin in the peripheral NS.

A

Schwann Cells

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127
Q

Frontal lobe is primarily for ________ function

A

Motor

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128
Q

Normal CPP

A

80–100mmHg

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129
Q

Which 3 sacral nerves are parasympathetic?

A

S2, 3, 4

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130
Q

Larger diameter nerves have _______ resistance to impulse conduction.

A

Less

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131
Q

2nd order pain and temperature neurons travel up these 2 tracts?

A

Anterior or Lateral Spinothalamic Tract

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132
Q

Chloride, Magnesium, and CO2 are ________ in the CSF than the Plasma

A

Higher in the CSF

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133
Q

The _______ neuron initiates in the CNS.

A

Preganglionic

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134
Q

When does BBB become 100% effective

A

4 months

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135
Q

Primary inhibitor NT in the CNS?

A

GABA

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136
Q

The ___ anterior spinal artery supplied ___ percent of blood flow to the spinal cord.

A

1

75

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137
Q

This space lied between the dura mater and the arachnoid matter?

A

Subdural (place where bleeding happens)

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138
Q

Spinal cord is ____cm shorter than the spinal column.

A

25

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139
Q

The total body O2 consumption is ______ per minute

A

250ml

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140
Q

Measuring ICP in the lumbar cistern can _____ ICP in patients with intracranial lesions

A

Underestimate

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141
Q

Glutamate activates inotropic receptors (such as ______) openingNa+channels and depolarizing the membrane to regulate intracellular ________ messenger systems

A

NMDA

2nd

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142
Q

Postganglionic sympathetic nerves and afferent sensory nerves for autonomic functions? They sense warm temp, slow pain, and itching?

A

C fibers

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143
Q

What is a white matter astrocyte?

A

Fibrous

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144
Q

If blood flow to that brain is not re–established within _____ minutes, ATP stores become depleted and irreversible cellular injury ensues.

A

3–8

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145
Q

The cerebral cortex is the outer _____mm

A

3

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146
Q

Most common incomplete circle of willis is due to a missing posterior _________ artery.

A

Communicating

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147
Q

Mu–1 is ____ spinal

A

Supra

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148
Q

How many thorax nerve pairs are there?

A

12

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149
Q

How many coccygeal nerve pairs are there?

A

1

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150
Q

What level is the arteria magna?

A

T8–T12

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151
Q

Is sensation lost with arteria magna ischemia?

A

No

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152
Q

Arteries that arise from intercostal and lumbar arteries?

A

Radicular

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153
Q

The ______ fissure marks to inferior border of the somatosensory and motor cortex

A

Slyvian

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154
Q

CBF is autoregulated between a CPP of ______

A

50–150

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155
Q

________ is found in large amounts within the cholinergic synapse.

A

Acetylcholinesterase

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156
Q
Most common neuron type in human CNS?
Mulitpolar
Bipolar
Psuedo-unipolar
unipolar
A

Multipolar

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157
Q

What structures are on the lateral edges of the Homunculus?

A

Tongue, Jaw, teeth, larynx

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158
Q

How many paired ganglia are there for sympathetic thoracolumbar outflow?

A

22

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159
Q

This cranial bone is just dorsal of the frontal bone in the medial skull

A

Sphenoid

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160
Q

What is the most inferior cranial nerve in Lafoon’s brainstem pic?

A

11 (Accessory)

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161
Q

What are the two different types of potassium channels on the axolemma?

A

Leak channels

Voltage Gated

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162
Q

What two states do local anesthetic bind during?

A

Open

Inactivated

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163
Q

What are 2 names for the artery of adam?

A

Arteria Magna

Greater radicular artery

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164
Q

Third order neurons travel in the internal capsule to eventually synapse in the __________.

A

Postcentral Gyrus

165
Q

What is responsible for establishing the RESTING state of the neuron?

A

ATPase pump

166
Q

The medial ________ terminates in the ventral posterolateral thalamic nucleus.

A

Lemniscus

167
Q

What is the formula for CPP?

A

MAP–ICP

Use CVP if greater than ICP

168
Q

Oligodendryocytes form myelin in the ______.

A

CNS

169
Q

What occurs in the cerebral vasculature if MAP or CPP fall below autoregulation threshold?

A

Cerebral Vasodilation (but decreased blood flow to brain)

170
Q

What fissure separates the anterior cerebellum from the posterior?

A

Primary Fissure

171
Q

Hyperthermia above ______ may result in neuronal injury

A

42 degrees

172
Q

Almost all sensory neurons are __________.

A

Pseudo–Unipolar

173
Q

The 3 main nerves that synapse in a distal collateral ganglion anterior to the vertebral column or close to the effector organ?

A

Celiac
Superior Mesenteric
Inferior Mesenteric

174
Q

How many sacral nerve pairs are there?

A

5

175
Q

What part of the brain are the red nucleus and substantia nigra found in?

A

Midbrain

176
Q

The CSF leaves the 4th ventricle median aperture through the foramen of ________.

A

Megendie

177
Q

The SNS has ______ preganglionic neurons and __________ postganglionic neurons. The PSNS is the opposite of this.

A

SNS = Short Pre, Long post

178
Q

This part of the limbic system helps control emotion, stress, response, pain, and appetite:

A

Amygdala

179
Q

State the 5 chambers in order of CSF flow.

A
  1. Lateral Ventricles
  2. 3rd ventricle
  3. 4th ventricle
  4. Cistern Magna
  5. Subarachnoid space
180
Q

What side of the spinal cord has the deep fissure?

A

Anterior

181
Q

What spinal tract is responsible for motor function of the trunk and extremities?

A

Corticospinal Tract

182
Q

NE has some inhibitory effects, particularly in the RAS and inhibition of impulses to the __________.

A

Cerebral cortex

183
Q

Sensory neurons always enter the spinal cord via the ______ matter and then enter the _____ matter before they ascend.

A

Enter through white

Ascend in gray

184
Q

Elevated convolutions on the cerebral surface

A

Gyri

185
Q

True or false: Intense hyperoxia can decrease CBF by 10%

A

TRUE

186
Q

How many lumbar vertebrae are there?

A

5

187
Q

True or false: In healthy patients in recumbent position, Lumbar ICP is the same as cranial

A

TRUE

188
Q

The CSF leaves the fourth ventricle and enters the cerebellomedullary _______ _________.

A

Cistern Magna

189
Q

This type of neuron is not found in humans.

A

Unipolar

190
Q

Shallow groove in the cerebral surface

A

Sulca

191
Q

Where do A–delta and C fibers have their cell bodies?

A

Dorsal Root Ganglion

192
Q

N/V, dizziness, and AMS are signs of CPP outside of ________

A

Autoregulation

193
Q

The brain consumes ___ percent of total body oxygen.

A

20%

194
Q

White matter is called the posterior or dorsal ________.

A

Column

195
Q

What percent of blood flow is from the internal carotids? How about the vertebrals?

A

70 ––– 30

196
Q

This sulcus divides the parietal and temporal lobe from the occipital lobe?

A

Parietal–occipital Sulcus

197
Q

The 50 divisions of the cerebral cortex with different functions?

A

Brodmann Area

198
Q

Vibration, discrete touch, and proprioception decussate to form the medial ________.

A

Lemniscus

199
Q

This space is present in the spinal column but not in the cranium. It is a potential” space in the cranium. It contains venous plexuses and fat.”

A

Epidural Space

200
Q

Amount of CSF produced per day

A

500–600mL

201
Q

What type of neurons ascend to the medulla BEFORE decussating and crossing over?

A

Vibration, discrete touch, proprioception

202
Q

If you’re ever asked the primary inhibitory CNS NT, it is _______

A

GABA

203
Q

Information from the cerebellum is transmitted to the _____ and to lower _____ neurons.

A

Cerebral Cortex

Motor

204
Q

State the 3 ways sympathetic nerves can exit the spinal cord

A

1: Synapse at the level of exit
2: Course up or down ganglia trunk
3: Synapse at an anterior collateral ganglion outside of the spinal cord close to the effector organ

205
Q

What is another name for the Flocculonodular lobe of the cerebellum?
What is it partly responsible for?

A

Archeo Cerebellum

Equilibrium

206
Q

The basal ganglia is between the two ______.

A

Cerebral hemispheres

207
Q

What enzyme converts Acetyl–CoA and Choline into Ach?

A

Choline Acetyltransferase

208
Q

The ATPase pump does it’s action after _______ has occured.

A

Repolarization

209
Q

How long does it take sodium to equalibrate between CSF and plasma?

A

4 hours

210
Q

What is the gray matter lateral horn responsible for?

A

Presynaptic Cell bodies from T1–L2

211
Q

Appropriate blood sugar for brain protection is less than ____

A

180

212
Q

The CSF leaves the 3rd ventricle through the cerebral aqueduct of _____ in the midbrain to the _______ ventricle.

A

Slyvius

4th

213
Q

The ______ matter is composed of cell bodies.

A

Gray

214
Q

What glial cell helps form myelin sheath, propagates nerve impulses, myelinates more than one axon?

A

Oligodendrocyte

215
Q

What type of reaction does acetylcholinesterase catalyze?

A

Hydrolysis

216
Q

CBF at which there is irreversible brain damage

A

10ml

217
Q

C fibers enter the substantia gelatinosa (RL 2,3) and then go to RL ____

A

5

218
Q

The cervical ganglion is divided into 3 division: Superior, Middle, and Inferior. Damage to which cervical ganglion causes Horner’s syndrome?

A

Superior Cervical Ganglion

219
Q

The anterolateral pathway”

A

Spinothalamic Tract

220
Q

The basal ganglia, red nucleus, substantia nigra, and reticular formation are __________ motor areas that play a role in ______ function.

A

Subcortical

Motor

221
Q

RMP in nerves is mostly determined by this ion:

A

Potassium

222
Q

This spinothalamic tract transmits nondiscrete, nonlocalized touch.

A

Anterior

223
Q

pH of CSF?

A

7.32

224
Q

Mu–2 is _______ spinal

A

Just spinal

225
Q

The primary mechanism behind termination of catecholamines

A

Presynaptic Reuptake

226
Q

The PSNS ganglia are located much closer to the __________.

A

Effector organ

227
Q

Remember that nerves ________ in the spinal cord.

A

Decussate

228
Q

How many total spinal nerves are there?

A

62

229
Q

True or false: CPP less than 30 causes a flat EEG

A

TRUE

230
Q

Where does the spinal cord start and end in adults?

A

Foramen Magnum

L1

231
Q

4 glial cells?

A

Astrocyte
Ependymal cell
Microglial
Oligodendrocyte

232
Q

You know cardiac RMP is –90. What is a nerve cell’s?

A

–70

233
Q

PNS postganglionic neurons release this NT:

A

Ach

234
Q

Threshold potential of a nerve cell

A

–30 to –50

235
Q

___________ have perivascular feet that play an important role in formation of the BBB.

A

Astrocytes

236
Q

True or false: CSF exists in the subarachnoid space of the brain and spinal cord?

A

TRUE

237
Q

This fold of the brain separates the occipital lobe from the cerebellum?

A

Tentorium Cerebella

238
Q

Hyperventilation to a PaCO2 less than 20 shifts the oxyhemoglobin curve to the __________.

A

Left

239
Q

This fold is part of the inner meningeal layer and separates the two cerebral hemispheres

A

Faux Cerebri

240
Q

How to remember the CSF specific gravity?

A

James Bond

241
Q

This cranial nerve is responsible for movement of the tongue, swallowing, and SPEECH?

A

Hypoglossal

242
Q

The ______ looks like a little ball.

A

Inactivation Gate

243
Q

Which 3 rexed laminae make up the ventral horn of motor neurons?

A

7, 8, 9

244
Q

Which two cranial nerves provide motor and sensory function to the face?

A

Trigeminal

Facial

245
Q

Interruption of cerebral perfusion results in unconsciousness within 10 seconds because of high ________ and lack of ______.

A

O2 Consumption

Reserve

246
Q

Primary inhibitory NT in the spinal cord?

A

Glycine

247
Q

Anything that interrupts the arteria magna can cause ________ paralysis from ischemia to the anterior spinal cord.

A

Motor neuron

248
Q

In patients with chronic HTN, CBF becomes more _______ dependent at low normal MAP

A

Pressure

249
Q

What is the one weird thing that is all the way at the lateral edge of the somatosensory homonculus?

A

Abdomen

250
Q

At 20 degrees, the EEG is _________, but further reduction will continue to reduce CMR.

A

Isoelectric

251
Q

Cerebral blood flow averages ______ml/100g/minute, because there is _____ml from the gray matter and _____ ml from the white matter

A

50

80 gray

20 white

252
Q

What matter does the reflex arc synapse occur in?

A

Gray Matter

253
Q

Which rami of the sympathetic ganglion is closer to the cord?

A

White

254
Q

This line divides the Frontal Lobe from the Parietal Love

A

Central Sulcus

255
Q

This cranial nerve is responsible for facial sensation and chewing?

A

Trigeminal

256
Q

Dural venous sinuses drain into the ______ sinus before draining into the IJ.

A

Sigmoid

257
Q

Primary excitatory NTM within the CNS?

A

Glutamate

258
Q

What are the two metabolic endpoints of acetylcholine breakdown?

A

Acetic Acid

Choline

259
Q

Cauda equina is a nerve group from L ___ to S ___.

A

L1 to S5

260
Q

CBF is proportional to PaCO2 between _____ to ____

A

20–80

261
Q

Pain and sensory fibers enter the pons where they form the _____ nerve.

A

Trigeminal

262
Q

What is another name for the Neo cerebellum?

What is it responsible for?

A

Posterior Lobe

Involuntary muscle coordination

263
Q

This organ is fed by one preganlgionic neuron and acts itself like a postganglionic neuron.

A

Adrenal Medulla

264
Q

2nd cervical vertebrae?

A

Axis

265
Q

First part of the brainstem responsible for auditory and visual processing?

A

Midbrain

266
Q

NE is releases from ______________ganglionic adrenergic neurons.

A

Post

267
Q

Which four cranial nerves are parasympathetic?

A

3, 7, 9, 10

268
Q

10 Divisions in the gray matter from ventral to posterior?

A

Rexed Laminae

269
Q

Duration of catecholamines is regulated by these 3 things:

A

Presynaptic Reuptake
MOA breakdown in nerve terminal
COMT breakdown in the liver

270
Q

90% of glucose is metabolized____ therefore CMRO2 normally parallels glucose consumption

A

Aerobically

271
Q

These 2 things make up the diencephalon (midline between hemispheres):

A

Thalamus

Hypothalamus

272
Q

These 7 things are lower in the CSF than the serum?

A
Potassium
Protein
pH
Calcium
Cholesterol
Glucose
HCO3
273
Q

Where do pain and sensory fibers from the head synapse before entering the pons?

A

Trigeminal Ganglion

274
Q

What is the key difference between the pain/temperature” tract and the “pressure and crude touch” tract?”

A

Pain/Temp: Lateral Spinothalamic Tract

Pressure and Crude: Ventral Tract

275
Q

The most interior meningeal layer that is adhered to the brain and spinal cord?

A

Pia Mater

276
Q

Local anesthetics cannot bind during the ________ state.

A

Resting

277
Q

What fibbers sense cold and pain?

A

A delta

278
Q

At birth, the spinal cord is ____________ as the spinal column.

A

The same length

279
Q

The A/P/L Funiculus makes up the _____ matter.

A

White

280
Q

When viewing the homunculus, remember that the area of the brain represents the ________ side of the body.

A

Contralateral

281
Q

Intracranial lesions result in decreased _______ pressure and increased ________ pressure

A

Decreased Infratentorial

Increase Supratentorial

282
Q

What column of the anterior spinal cord contains preganglionic sympathetic neurons?

A

Intermediolateral

283
Q

At PaCO2 levels greater than 80, CBF will be _______ than PaCO2

A

Less

284
Q

This part of the limbic system is important for learning and memory formation:

A

Hippocampus

285
Q

CSF is _______ with plasma but electrolyte and other component concentrations differ.

A

Isotonic

286
Q

These 3 areas of the brain are most sensitive to hypoxic injury

A

Hippocampus
Cerebellum
Thalamus

287
Q

What glial cell resembles a dendrite?

A

Microglia

288
Q

Overlap in cutaneous dermatomes is due to pain and temperature fibers traveling up and down the _____________ before entering the RL

A

Tract of Lissauer

289
Q

Specific gravity of CSF?

A

1.007

290
Q

__________ SNS nerve exits the spinal cord gray unmyelinated.

A

Postganglionic

291
Q

What ICP requires treatment?

A

20

292
Q

What opposes calcium at the NMJ to prevent pain?

A

Magnesium

293
Q

Layers that holds bundles of parallel fasciles?

A

Epineurium

294
Q

The activation gate during looks like a ______.

A

Weiner

295
Q

________ area is just in front of the ear. ______Area is just behind the ear.

A

Broca’s in front.

Wernicke’s in back.

296
Q

Glial cell transported to sites of neuronal injury, develop into macrophages, and play a part in phagocytosis?

A

Microglial Cells

297
Q

_____ganglionic nerves are myelinated.

A

Pre

298
Q

The postecentral gyrus is also referred to as the primary _______________.

A

Sensory Cortex

299
Q

This bone makes up the posteriorlateral 2/3s of the skull

A

Parietal

300
Q

CBF at which the cerebrum is impaired

A

25

301
Q

Where does the spinal cord end in the newborn?

A

L3

302
Q

This cranial bone is in the middle of the frontal bone?

A

Ethmoid

303
Q

The Auerbach Mesenteric plexus is the only sympthetic nerve in which one nerve may synapse to ______ cells.

A

8000

304
Q

What NT is involved with neuronal injury after ischemia and TBI?

A

Glutamate

305
Q

What ion is either the same or HIGHER in the CSF than the plasma?

A

Sodium

306
Q

Total CSF volume

A

150mL

307
Q

A beta fibers are for what?

A

Touch and Pressure sensation.

308
Q

What is another name for the paleo cerebellum? What is it responsible for?

A

Anterior Lobe

Muscle tone

309
Q

These two areas are just between Broca’s and Wernicke’s area?

A

Auditory association, Auditory Cortex

310
Q

Brain is _____% of body weight

A

2%

311
Q

When sodium channels become inactivated during the absolute refractory period, these channels open to release this ion that causes repolarization.

A

Potassium

312
Q

Water crossis BBB due to __________

A

Osmosis

313
Q

The tentorium cerebella marks the border between the __________ and _________ space.

A

Supratentorial

Infratentorial

314
Q

Name 4 endogenous opiods

A

Endorphin
Enkephalin
Dynorphin
Endomorphin

315
Q

What meningeal layer is closely adhered to the spinal cord?

A

Pia

316
Q

The vagus nerve makes up _______ of PSNS activity.

A

75%

317
Q

CPP is mostly dependent on _____

A

MAP

318
Q

How many pairs of spinal nerves are there?

A

31

319
Q

What type of neuron is special sensory in the eyes, nose, and ears?

A

Bipolar

320
Q

What is the pnemonic device for remembering which cranial nerves are motor and which ones are sensory?

A

Some Say Marry Money But My Brother Says Big Boobs Matter More

321
Q

True or false: Bladder dysfunction and paraplegia are possible due to arteria magna ischemia

A

TRUE

322
Q

The basal ganglia is involved in the control of ________. It is also a part of the _________ pathway.

A

Movement

Reward

323
Q

This space contains vascular structures, can produce hematoma? It is just below the arachnoid mater.

A

Subarachnoid space

324
Q

The CSF leaves the lateral ventricles through the foramen of ________ into the ________ ventricle.

A

Monro

3rd

325
Q

MS, ALS, tumors, HTN, and seizures can disrupt the

A

BBB

326
Q

CMRO2 averages _____ O2/100g/minute, or ______ ml/minute in adults.

A

3–3.8

50

327
Q

The olfactory bulb is located just under the _________

A

Frontal Lobe

328
Q

CSF is found in ventricles and ______ in the brain.

A

Cisterns

329
Q

What is the smallest A fiber?

A

A delta

330
Q

Connective tissue around each axon within a fascicle?

A

Endoneurium

331
Q

CBF is _____ percent of CO

A

15–20%

332
Q

Compensatory decrease in cerebral blood volume is primarily decreased _________ blood

A

Venous

333
Q

______ganglionic nerves are non–myelinated

A

Post

334
Q

What side of the spinal cord has the shallow median sulcus?

A

Posterior

335
Q

Myelinated neurons require _______ energy to power the ATPase pump.

A

Less

336
Q

Schwann cells can form myelin around _____ axons.

A

1

337
Q

The ability of vessels to STRETCH with pressure changes?

A

Elastance

338
Q

What NT is involved in memory formation during GA awareness?

A

Glutamate

339
Q

Why would polycythemia and COPD cause decreased CBF?

A

Increases Hct and Viscosity

340
Q

Deeper grooves in the cerebral surface

A

Fissuers

341
Q

CBF is directly proportional to _______ between tensions 20–80. 1 ml increase = 1 mmHg change

A

PaCO2

342
Q

Most parasympathetic nerves synapse at this ratio

A

1:1

343
Q

What glial cell supports neurons and provides nutrition and repair?

A

Astrocyte

344
Q

Gray matter is called the posterior or dorsal ____________.

A

Horn

345
Q

Normal ICP

A

5–15 mmHg

346
Q

What is the most superior cranial nerve on lafoon’s picture of the brainstem?

A

3 Oculomotor

347
Q

These three things play an important role in the formation of the BBB

A

Pericytes
Tight Junctions
Perivascular Feet

348
Q

The reticular formation found in brainstem and diencephalon contain extensor and _____ neurons.

A

Flexor

349
Q

This part of the limbic system regulates body functions:

A

Hypothalamus

350
Q

Brainstem and cerebellum are in the ______ fossa

A

Posterior

351
Q

This inhibitory NT is predominant in the basal ganglia?

A

Dopamine

352
Q

CBF at which the EEG is isoelectric

A

20

353
Q

The ability of vessels to RECOIL back to normal dimension?

A

Compliance

354
Q

What matter is shaped like a butterfly in the spinal cord?

A

Gray matter

355
Q

GABA activation opens __________ channels producing hyperpolarization.

A

Chloride

356
Q

What large cranial nerve exits the spinal cord on the anterior side just inferior to the pons? It is out of order of the rest of them?

A

12 (Hypoglossal)

357
Q

True or false: The axolemma is permeable to potassium, sodium, and calcium at rest.

A

FALSE: Potassium only

358
Q

The axon hillock is the point at which the axon meets the _______

A

Cell Body

359
Q

The trochlear nerve is responsible for _____ movement.

A

Eye

360
Q

At what age does the spinal cord end up at L1?

A

2 years

361
Q

As PaO2 decreases, CBF ________

A

Increases

362
Q

What type of Ach receptors are in smooth muscle, sweat glands, and cardiac muscle?

A

Muscarinic

363
Q

True or false: Water can move through the BBB freely.

A

TRUE

364
Q

What layer is between the scalp and the skull bone?

A

Periostemum

365
Q

How many sacral vertebrae are there?

A

5

366
Q

Neurons have voltage gated ______ channels that open in response to a stimulus.

A

Sodium

367
Q

This line divides the R and L hemisphere

A

Longitudinal Fissue

368
Q

What mechanism does the brain use to lower ICP until HCO3 can compensate? How long does it take for HCO3 compensation?

A

Hyperventilation

6–12 hour

369
Q

How many lumbar nerve pairs are there?

A

5

370
Q

How many coccygeal vertebrae are there?

A

4

371
Q

2 types of cells in the CNS

A

Neuron

Glial

372
Q

A gamma fibers are for what?

A

Skeletal muscle tone

373
Q

Neurons that connect adjacent neurons in the CNS

A

Interneurons

374
Q

Inhibitor NTM affecting mood

A

Serotonin

375
Q

The brain consumes ______ of the total body glucose

A

25%

376
Q

True or false: CPP less than 50 often shows slowing on the EEG and signs of ischemia

A

TRUE

377
Q

This precursor to tyrosine make epi, NE, Dopamine?

A

Phenylalanine

378
Q

What happens when elastance and volume compensation mechanism reach exhaustion?

A

Herniation

379
Q

Middle fossa holds what 2 lobes

A

Temporal, Parietal

380
Q

1st cervical vertebrae?

A

Atlas

381
Q

Connective tissue around each individual fascicle?

A

Perineurium

382
Q

What do the ependymal cells form?

A

Choroid Plexus

383
Q

Largest radicular artery that supplies 2.3 of spinal cord blood flow?

A

Adamiewicz

384
Q

80% of cranium is ______

A

Brain

385
Q

Serum Osmolality ______CSF Osmolality

A

Equals

386
Q

What depression is in the sphenoid bone? What does this contain?

A

Sella Turcica

Pituitary Gland

387
Q

2 names for the cell body

A

Soma

Perikaryon

388
Q

The ependymal cells are in the central _____________ and the roof of the _______ and ______ ventircles of the brain.

A

Spinal Canal

3rd and 4th

389
Q

CSF pressure?

A

5–15mmHg

390
Q

What is a gray matter astrocyte?

A

Protoplasmic

391
Q

This fissure divides the frontal and parietal lobe from the temporal lobe?

A

Sylvian Fissure

392
Q

Brain glucose consumption is approximately ___mg/100g/minute

A

5mg

393
Q

Middle section of the brainstem, anterior to the cerebellum?

A

Pons

394
Q

ICP refers to ______ CSF pressure

A

Supratentorial

395
Q

CMRO2 is greatest in the ________ matter of the cerebral cortex and parallels ______

A

Gray Matter

Electrical Acivity

396
Q

What type of receptors are at the NMJ and between pre–postsynaptic membranes?

A

Nicotinic

397
Q

Decreased hematocrit decreases viscosity and improves CBF. What is the optimum Hct for CBF?

A

30%

398
Q

What is the predominant glial cell?

A

Astrocyte

399
Q

This section of the brainstem is where a lot of anesthetics work on?

A

RAS

400
Q

These three structures are the primary components of the limbic system:

A

Amygdala
Hippocampus
Hypothalamus

401
Q

10% of motor neurons go through the medulla and down the ____ corticospinal tract before crossing over in the gray matter.

A

Anterior

402
Q

Temporal lobe is primarily for _____ function

A

Auditory

403
Q

What nerve fibers make up preganglionic autonomic nerves?

A

B fibers

404
Q

Intense SNS stimulation induces vaso__________ and can ______ CBF

A

Constriction

Decrease

405
Q

The ____ is the most exterior or superficial layer of the brain. It is also the thickest.

A

Dura

406
Q

The fasciculus gracilis transmits sensory information from which areas of the body?

A

Lumbar and sacral

407
Q

The fasciculus cuneatus transmits sensory information from which areas of the body?

A

Thoracic and cervical

408
Q

A-delta pain fibers synapse in which rexed lamina?

A

lamina 1 and 5

409
Q

C fibers synapse in which rexed lamina?

A

lamina 2 and 3, then synapse with interneurons to rexed lamina 5