A Megaloblastica Flashcards

1
Q

Sinomime

A

A pernicioasă, boala Addison Biermer

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2
Q

Def

A

A macrocitara si normocroma det de carenta vit B12 sau a acidului folic sau alte defecte in sinteaz ADN ului

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3
Q

Vit b12

A

Orig alimentatia animala
Absorbtie complexul FI -B12 ileonul terminal
Transport transcobalamina I si II
Depozit ficat
2 forme :
.metilcobalamina respons de tulb hematologice si digestv
.adenozilcobalamina tul nervoase

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4
Q

Cauze

A

Scade apoetul alim vegetariana
Tulb de absortie ;lipda factorului intridec
Afect ileon terminal b crohn
Rezestii intestinale

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5
Q

Vit b12 valori normale

A

243-894pg/ml

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6
Q

Valori fals scazute

A

Sarcina
Varstnici
Leucocite scazute

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7
Q

Acidul metilmalonic test specific si sensibil

A

VN=19-76ng/ml

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8
Q

Anemia macricitara NON-Megaloblastica

A

Hipotiroidism

TSH crescut si FT4 scazut

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9
Q

A megalobl trat

A

Ciancobalamina trat 1 luna
Folat doza pe zi 1mh/zu pana 5 mg timp 1 luna
Acid folic:rinichii, ficatul, legumele verzi spanac brocoli avocado mazare

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