96 Hemolytic Flashcards
What is commonly seen in hemolytic anemia?
Increased MCV and MCH
Main sign of hemolytic anemia that differentiates it from other anemia
Jaundice
Laboratory features wheh hemolysis is extravascular
Increase unconjugated/Indirect bilirubin
Increased AST/SGPT
Urobilinogen in urine and stool
Laboratory feature if hemolysis is intrvascular
Hemoglobinuria
Increased free hemoglobin
Increased LDH
Reduced haptoglobin
Main sign of Erythropoietin response in the marrow and too often neglected in initial work up of anemia
Reticulocyte count
True or false. Increase in Reticulocyte count also lead to increased MCV
True
Essential pathophysiologic process common to all hemolytic anemia
Increased red cell turnover
Most abundant red cell membrane proteins
Glycophorins
Band 3
Potent stimulus for erythropoiesis
Red cell destruction
Main cytoskeleton protein
Spectrin