59 Anemia and Polycythemia Flashcards
1
Q
Least useful of the RBC indices
A
MCH
2
Q
How is Reticulocyte Production Index computed
A
Hgb/15 divided by maturation factor x Reticulocyte count
3
Q
Hct and it’s correction factor. 45, 35, 25, 15
A
45 - - 1.0
35 - - 1.5
25 - - 2.0
15 - - 2.5
4
Q
Anemia. RPI less than 2.5. Normocytic. Normochromic
A
Hypoproliferative anemia IDA Renal disase Metabolic defect Inflammation
5
Q
Anemia RPI less than 2.5. Micro/macrocytic
A
Maturation disorder === Cytoplasmic IDA Thalassemia Sideroblastic === Nuclear defects Folate deficiency Vit B12 deficiency Drug toxicity Myelodysplasia
6
Q
Define as increase in hemoglobin above normal
A
Polycythemia
7
Q
Erythrocytosis vs polycythemia
A
Erythrocytosis: increase in red cell mall
Polycythemia: increase in red cell numbers
8
Q
This physical examination favors Polycythemia Vera in case of increased hemoglobin
A
Splenomegaly
9
Q
In the approach to Polycythemia, what is the first step?
A
Document the increase red cell mass
10
Q
Increased hgb/Hct. RBC mass normal
A
Relative erythrocytosis
