9: Treatment Options

Question 1

T/F Some chemotherapy drugs are considered chemo only when used in combination with other drugs.

Answer 1

True. For example, dexamethasone is chemo when combined with velcade and cytoxan for multiple myeloma.

Question 2

Which stage of the cell cycle: G0, G1, S, G2, or M?

Mitosis (cell splits into 2).

Answer 2

M

Question 3

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Adriamycin, Bleomycin.

Answer 3

Antitumor antibiotics

Question 4

Photon or particle ionizing radiation?

Protons

Answer 4

Particle (ionizing) radiation

Question 5

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Stop mitosis or inhibit enzymes from making proteins required for cell reproduction.

Answer 5

Mitotic inhibitors

Question 6

T/F Watchful waiting can make some patients uncomfortable, but some cancers may not require therapy for years.

Answer 6

True. Chronic lymphocytic leukemia you monitor in the WBC. May not require treatment for years.

Question 7

Which stage of the cell cycle: G0, G1, S, G2, or M?

Apparatus for mitosis is built.

Answer 7

G2

Question 8

Which stage of the cell cycle: G0, G1, S, G2, or M?

RNA and protein synthesis are made for dividing.

Answer 8

G1

Question 9

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Interfere with enzymes called topoisomerases (help separate strands of DNA for replication).

Answer 9

Topoisomerase inhibitors

Question 10

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Taxol, Taxotere, Vincristine

Answer 10

Mitotic inhibitors

Question 11

T/F Radiation effects can linger for decades.

Answer 11

True. Uncommon, but can increase secondary malignancies or cause idiopathic pulmonary fibrosis, for example.

Question 12

Photon or particle ionizing radiation?

Electrons

Answer 12

Particle (ionizing) radiation

Question 13

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Irontecan, Etoposide

Answer 13

Topoisomerase inhibitors

Question 14

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Cytoxan, Cisplatin, platinum-based therapies.

Answer 14

Alkylating agents

Question 15

Photon or particle ionizing radiation?

Neutrons

Answer 15

Particle (ionizing) radiation

Question 16

_____ is hormone therapy used to treat prostate cancer.

Answer 16

Lupron

Question 17

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
5-FU, Pemetrexed

Answer 17

Antimetabolites

Question 18

Which stage of the cell cycle: G0, G1, S, G2, or M?

DNA synthesis.

Answer 18

S

Question 19

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Interfere with DNA and RNA growth, specifically during S phase.

Answer 19

Antimetabolites

Question 20

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Commonly used to treat ovarian cancer.

Answer 20

Alkylating agents

Question 21

Photon or particle ionizing radiation?

Gamma rays

Answer 21

Photon (ionizing) radiation

Question 22

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Can cause neuropathy.

Answer 22

Alkylating agents

Question 23

Cancer management (4).

Answer 23

1. Watchful waiting
2. Chemo
3. Radiation
4. Surgery

Question 24

Photon or particle ionizing radiation?

Most widely used in cancer treatment.

Answer 24

Photon (ionizing) radiation

Question 25

Photon or particle ionizing radiation? | X-rays

Answer 25

Photon (ionizing) radiation

Question 26

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors? Directly damage DNA and prevent cancer cells from reproducing and growing.

Answer 26

Alkylating agents

Question 27

T/F Debulking surgery is common for most solid tumors.

Answer 27

True. It can help relieve symptoms.

Question 28

Which stage of the cell cycle: G0, G1, S, G2, or M? | Cell rests from dividing and does its normal physiologic work.

Answer 28

G0

Question 29

Tarceva targets the _____ mutation in lung cancer patients.

Answer 29

EGFR

Question 30

During which cell cycle is radiation least effective?

Answer 30

G0 (slowly dividing)

Question 31

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors? Interfere with enzymes involved in DNA replication.

Answer 31

Antitumor antibiotics