9. Parasite strategies Flashcards

1
Q

How do parasites usually enter our bodies?

A
  • anus to mouth (usually via fingers)
  • nose/mouth in the air
  • through the skin
  • sexual intercourse
  • via intermediate host/vector
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2
Q

What are the different ways parasites can enter via intermediate hosts?

A
  • intermediate host is eaten
  • carried into the final - scratched in (ie. lice)
  • injected into final host
  • in the water and then penetrate the skin
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3
Q

What happens if we are the intermediate host?

A
  • usually harmless if cysts are in the meat we ear
  • worms colonise our gut

•its bad if we put eggs in our mouth - oncospheres develop in out muscles

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4
Q

Why is dog tapeworm even more dangerous?

A
  • hydatid (big) cysts develop in the liver and other organs

* need surgery and chemotherapy

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5
Q

Why do insects/ticks make excellent vectors for microparasites?

A
  • often highly mobile
  • actively search for new hosts
  • mouthparts adapted to penetrate the skin barrier
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6
Q

Sleeping sickness vector

A

Tsetse fly

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7
Q

Malaria vector

A

Mosquito

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8
Q

Leishmaniasis vector

A

Sand flies

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9
Q

Chagas’ disease vector

A

Assassin bug

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10
Q

Bubonic plague vector

A

Fleas

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11
Q

Typhus vector

A

lice

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12
Q

What the different strategies that parasites use to survive in our bodies?

A
  1. Many copies, genetically variable
  2. avoid recognition
  3. present a moving target
  4. hide from defenders
  5. attack
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13
Q

How do parasites avoid recognition and give example

A

• Schistosome (class trematoda) use camouflage

Live in the blood vessels-
• avoid attack by coating themselves with host antigen proteins
• also produce enzymes that destroy or detach complement proteins

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14
Q

Presenting a moving target and examples

A
  • trypanosomes (protists - kinetoplastids)

* can make 1000 different surface antigens

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15
Q

Hide from defenders examples

A

In gut
• tape worms, hook worms
• low risk as immune system is not strong in the gut

Inside cells
• plasmodium and trichinella spiralis in muscle cells
• it then makes the cell grow and get extra blood supplies

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16
Q

Attack examples

A

HIV (causal agent of AIDS)
• destroys the immune system of host
• invades and divides in various immune cells
• disruption of cellular immune response
• leaves infected person vulnerable to other infections

17
Q

What does the complex life cycle of a parasite usually entail?

A
  1. inert stages
    - survive a long time, wait for host
  2. free living stages
    - feed and wait for host
  3. use an intermediate host
    - way to get into final host
  4. asexual multiplication
    - many copies, many chances for dispersal
  5. sexual reproduction
    - ensure variation
18
Q

How is human/pig roundworms transmitted

A
  • eggs swallowed on food, hatches in gut, penetrated gut wall
  • egg pass out in feces and onto raw vegetables
19
Q

Final and intermediate host of Hydatid tapeworm

A
  • intermediate
  • sheep eat eggs
  • cysts form in organs and meat is eaten

Final
• human or dog
• cyst wall digested and attaches to intestine before growing into tapeworms

20
Q

What type of reproduction occurs in final host?

A
  • Sexual
  • ensures variation
  • to ensure mates and double number of egg producers
21
Q

What type of reproduction occurs in the intermediate host?

A
  • asexual
  • many copies
  • higher chance of entering new host
  • dispersal
22
Q

Final and Intermediate host of Schistosoma spp

A
  • eggs pass in feces and hatch in water
  • go into snail and form many daughter redia (asexual)

Final
• cercariae leave snail to find warm skin (ie humans)
• penetrate skin and migrate into lungs

23
Q

Define vector

A

Intermediate hosts that transport parasites between final hosts