9: Lumbar Spine & Spinal Conditions Flashcards

1
Q

what is mechanical back pain

A
  • characterised by pain when the spine is loaded that worsens w exercise and is relieved by rest
  • tends to be intermittent and often triggered by innocuous activity
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2
Q

what are risk factors for mechanical back pain

A
  • obesity
  • poor posture
  • sedentary lifestyle w deconditioning of paraspinal muscles
  • poorly designed seating and incorrect manual handling
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3
Q

what are degenerative changes that can take place in the vertebral column

A

disc degeneration and marginal osteophysis
- nucleus pulposus of the intervertebral discs dehydrate w age which leads to decreased height, bulging of discs and alteration of the load stresses on the joint
- osteophytes called syndesmophytes develop adjacent to end plates of the discs = MO
- increased stress on facet joint = osteoarthritic changes
- facet joints innervated by meningeal branch of spinal nerve so arthritis in these joints perceived as painful
- with this, intervertebral foramina decrease in size –> compression of spinal nerves (radicular/nerve pain)

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4
Q

why does pain occur in ‘slipped disc’

A

due to herniated disc material pressing on a spinal nerve

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5
Q

what are the four stages of a disc herniation

A
  1. disc degeneration: chemical changes associated w ageing –> dehydration and bulging of disc
  2. prolapse: protrusion of nucleus pulposus (contained within rim of annulus fibrosus) occurs w slight impingement into spinal canal
  3. extrusion: NP breaks through AF but still contained within disc space
  4. sequestration: NP separated from main body of disc and enters spinal canal
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6
Q

at which two sites are the nerve roots most vulnerable

A
  1. where they cross the intervertebral disc (paracentrally)
  2. where they exit the spinal canal in the intervertebral foramen (far laterally)
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7
Q

how does the nucleus pulposus most commonly herniate

A

posterolaterally, causing compression of a spinal nerve root within the intervertebral foramen
- known as a paracentral prolapse and occurs in 96% of cases
- 2% cases = ‘far lateral’ herniation
- 2% = central i.e. directly towards the spinal cord

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8
Q

which nerve is most at risk in ‘far lateral’ disc herniation

A

exiting nerve root
- this is the nerve root that emerges from the spinal canal at the same level as the intervertebral disc

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9
Q

which nerve is most at risk in a paracentral herniation

A

traversing nerve root
- so in a paracentral herniation of L4/L5 disc, L5 root = most frequently compressed

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10
Q

what does central herniation carry risk of

A

cauda equina syndrome

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11
Q

what is sciatica

A

pain caused by irritation or compression of one or more of the nerve roots that contribute to the sciatic nerve (L4,L5, S1-3)
- if the nerve compression also causes paraesthesia, this will be only experienced in the affected dermatome (rather than the full path from lumbar spine to dermatome)

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12
Q

causes of sciatica (2)

A
  • marginal osteophytosis
  • slipped disc
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13
Q

where is sciatica pain typically experienced

A

back and buttock and radiates to the dermatome supplied by the affected nerve root

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14
Q

pain distribution of L4 sciatica

A

anterior thigh, anterior knee and medial leg

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15
Q

pain distribution of L5 sciatica

A

lateral thigh, lateral leg and dorsum of foot

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16
Q

pain distribution of S1 sciatica

A

posterior thigh, posterior leg, heel and sole of foot

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17
Q

what is cauda equina syndrome and what are its causes

A
  • can develop in context of prolapsed intervertebral disc when there is ‘canal filling disc’ that compresses lumbar and sacral nerve roots within spinal canal
  • causes:
    - disc prolapse
    - primary/secondary tumours affecting vertebral column/meninges
    - spinal infection/abscess
    - spinal stenosis secondary to arthritis
    - vertebral fracture
    - spinal haemorrhage
    - late stage ankylosing spondylitis (inflamm condition affecting spine)
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18
Q

red flag symptoms of cauda equina syndrome

A
  • bilateral sciatica
  • perianal numbness
  • painless retention of urine
  • incontinence
  • erectile dysfunction
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19
Q

how is cauda equina syndrome treated

A

surgical decompression within 48 hours of the onset of sphincter symptoms or poor prognosis

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20
Q

consequences of missing a diagnosis of cauda equina syndrome

A
  • chronic neuropathic pain
  • impotence
  • intermittent self-catheterisation
  • faecal incontinence
  • loss of sensation
  • lower limb weakness requiring wheelchair
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21
Q

what is spinal canal stenosis

A

abnormal narrowing of the spinal canal that compresses either the spinal cord or the nerve roots

22
Q

causes of spinal canal stenosis

A

tends to affect elderly and often due to combo of:
- disc bulging
- facet joint OA
- ligamentum flavum hypertrophy

other causes:
- compression fractures of the vertebral bodies
- spondylolisthesis
- trauma

23
Q

symptoms of spinal canal stenosis

A

symptoms depends on region of cord or nerve roots that affected w lumbar stenosis being most common, then cervical stenosis

  • Discomfort whilst standing (95% of patients)
  • Discomfort or pain in the shoulder, arm or hand (for cervical stenosis) or in the lower limb (for lumbar stenosis)
  • Bilateral symptoms in approximately 70% of patients
  • Numbness at or below the level of the stenosis
  • Weakness at or below the level of the stenosis
  • Neurogenic claudication
24
Q

neurogenic claudication

causes, symptoms, treatment

A
  • symptom rather than diagnosis
  • pt reports pain and/or pins and needles in legs on prolonged standing and on walking, radiating in a sciatica distribution
  • results from compression of spinal nerves as they emerge from lumbosacral spinal cord –> venous engorgement of nerve roots during exercise –> reduced arterial inflow and transient arterial ischaemia
  • ischaemia of affected nerve –> pain and/or paraesthesia
  • can be present in one or both legs
  • clasically relieved by change in position and flexion of the spine
25
Q

what is spondylolisthesis

A

anterior displacement of the vertebra above relative to the vertebra below

26
Q

classifications of spondylolisthesis

A
  • congential/dysplastic: congential instability of the facet joints
  • isthmic: defect in pars interarticularis
  • degenerative: facet joint arthritis and joint remodelling (>50)
  • traumatic: acute fractures in neural arch (no pars interarticularis)
  • pathological: infection/malignancy
  • iatrogenic: surgical intervention e.g. too much lamina/facet joint excised during laminectomy operation
27
Q

isthmic type of spondylolisthesis

A

defect (e.g. stress fracture) develops in the pars interarticularis which is the part of the vertebra between superior and inferior articular processes
- complete fracture w/out displacement = spondylolysis
- once anterior displacement of upper vertebra occurs = spondylolisthesis which may or may not be associated w gross instability of the vertebral column

28
Q

symptoms and treatment of spondylolisthesis

A
  • some individuals asymptomatic but most complain of discomfort from lower back pain to incapacitating mechanical pain, sciatica from nerve root compression and neurogenic claudication
  • treatment: using screws and rods to stabilise the spine
29
Q

how do you spot spondylolysis

A

trace outline of ‘scottie dog’ in oblique view of spine

30
Q

how can you detect grossly-displaces spondylolisthesis

A
  • trace line of anterior and posterior longitudinal ligaments to detect ‘step’ at site of displacement
31
Q

what is a lumbar puncture

A

withdrawal of fluid from the subarachnoid space of the lumbar cistern
- important diagnostic test for variety of CNS disorders e.g. meningitis, MS, etc

32
Q

how is a lumbar puncture performed

A
  • pt lying on side with back and hips flexed i.e. knee to chest
  • flexion of vertebral column facilitates insertion of needle by spreading the laminae and spinous processes apart thereby stretching ligamentum flavum
  • skin covering lower lumbar vertebrae anaesthetized and LP needle inserted in midline between spinous processed of L3/L4 or L4/L5 vertebrae
  • can be located by finding the plane transecting the highest points of the iliac crests—the supracristal plane—this usually passes through the L4 spinous process (no danger of damaging spinal cord here)
  • pass needle 4-6cm, which will pop through ligamentum flavum, puncturing dura and arachnoid then enters lumbar cistern
  • when stylet removed, CSF escapes then collected
33
Q

in a LP, state the structures through which the needle will pass from skin to subarachnoid space

A
  1. skin
  2. subcutaneous fat
  3. ligamentum flavum
  4. epidural fat and veins
  5. dura mater
  6. arachnoid mater
  7. subarachnoid space
34
Q

spinal nerves

A
35
Q

herpes zoster (shingles)

A
  • viral infec. which almost always affects the skin of a single dermatome
  • reactivation of chickenpox (Varicella zoster virus)
  • virus travels through cutaneous nerve and remains dormant in dorsal root ganglion after chickenpox
  • when host = immunosuppressed, VZV reactivates and travels through peripheral nerve to skin of a single dermatome
36
Q

what is a motor unit

A

single motor neuron and the skeletal muscle fibres it innervates

37
Q

what are the most common sites for ‘slipped discs’

A

L4/5
L5/S1
- due to mechanical loading at these joints

38
Q

what is the most common form of spinal infection

A

infection of vertebral body - spondylitis

39
Q

what are differentials for spinal infection

A
  • vertebral osteomyelitis
  • discitis: isolated infection of the IV disc namely nucleus pulposus; children
  • epidural abscess: space between dura mater and vertebral column; 50-70M
  • subdural abscess: space between dura and arachnoid
  • spinal cord abscess
40
Q

what are the main risk factors for spinal infections

A
  • IV drug use
  • immunosuppression
  • malignancy
  • DM
  • recent spinal surgery
41
Q

what is the typical presentation of a spinal infection

A
  • back pain which is worse on movement and worse at night
  • associated w pyrexia + radicular signs
  • O/E: focally tender at level of infection
42
Q

what investigations are inidicated in spinal infection

A
  • routine bloods: FBC, CRP, U&Es, LFTs + cultures
  • imaging: MRI (gold standard) + CT (to show extent of bony involvement)
43
Q

what investigation is indicated in confirmed cases of spinal infection

A

CT-guided biopsy to obtain samples for microbiology and histology
- help w abx choice

44
Q

what is the management of spinal infection

A
  • long term IV abx ~6 weeks for discitis
  • immobilisation in significant pain or spinal instability
45
Q

when is surgical intervention indicated in spinal infections

A
  • evidence of significant bone destruction causing bone instability
  • neuro deficits
  • poor response to antimicrobial treatment
46
Q

what are the goals of surgery in spinal infection

A
  • debride infected tissue
  • drain residual pus
  • restore spinal stability
47
Q

how is response to treatment monitored in spinal infection

A
  • look at symptoms
  • inflamm markers
  • repeat MRI
48
Q

what are red flags of back pain

A
49
Q

what are risk factors of spinal tumours

A
  • genetic conditions e.g. neurofibromatosis 1/2, Tuberous sclerosis, Von Hippel-Lindau, Li-Fraumeni
  • elevated radiation exposure
  • previous malignancies
  • FHx
50
Q

what is the 1st line investigation for a suspected osteoporotic vertebral fracture

A

X-ray spine