9 Gram Positive Anaerobic Rods (Infectious Bacterial Agents) Flashcards
1
Q
Clostridium Perfringens
A
- Gram (+) large rods, anaerobic
- Normal flora
- Virulence: alpha toxin, enterotoxin, degradative enzymes
- Clincal: Myonecrosis (GAS GANGRENE), Foodborne illness
2
Q
Clostridium Botulinum
A
- Gram (+) large rods, anaerobic
- Most potent toxin known
- AB Toxin
- Category A bioterrorism agent
- Blocks ACh release, FLACCID PARALYSIS
- Clinical: Classical botulism, Infant botulism (floppy baby syndrome) NO HONEY FOR INFANTS < 1 YO
3
Q
Clostridium Tetani
A
- Gram (+) rods w/terminal spores (RACKET SHAPED)
- Puncture would causes TETANUS and “LOCKJAW” PARALYSIS
- AB Toxin
4
Q
Clostridium Difficile
A
- Gram (+) rods, anaerobic
- Antibiotic associated diarrhea and pseudomembranous colitis (PMC)
- Virulence: Enterotoxin A and B
