9. Evaluating Data On Phenotypes Flashcards
What is a phenotype ?
Organismas genotuoe and the interactsction of genotype with environment
Example
Over eating
Was thought to be environmental - more food in developed countries
Food consumption increases brain dopamine levels in animals one enough dopamine was released people would stop eating
People with one particulate allele has 30% fewer dopamine receptors - more likely to overeat - wouldn’t stop eating when dopamine levels increases
Antioxidants
Exmpale
Many foods contain amgioxidants - prevent chronic diseases
Berries contain high levels of antioxidants - plants which produced them contained different levels of antioxidants bextSe of genetic factors.
Environmental conditions called great variation so both genetic and environmental
Identical twins
Differences in phenotype must be entirely down to environmental factors
Very similar epigenetic markers when born.
If characteristic is very similar in both twins that was probably genetic but characteristic is different environment would have played bigger role - diet / excerise
Alzheimer’s diseases in identical twins and non identical twins
Diseases has genetic risk
But disease not always found in both twins which suggest that environmental factors also play a part
Genetics account for 80% of risk
Why need lots of twins?
Valid conclusions
Small sample less representative of population