[9] Acute Pericarditis Flashcards
What is pericarditis?
Inflammation of the sac surrounding the heart
What is acute pericarditis?
A type of pericarditis usually lasting less than 6 weeks
What are the causes of pericarditis?
- Idiopathic
- Viruses
- Bacteria
- Fungi
- Parasites
- Autoimmune system
- Drugs
- Metabolic abnormalities
- Trauma
- Surgery
- Malignancy
- Radiotherapy
- MI
- Chronic heart failure
What are the viral causes of pericarditis?
- Coxsackie
- Echovirus
- EBV
- CMV
- Adenovirus
- Mumps
- Varicella
- HIV
What are the bacterial causes of pericarditis?
- TB
- Lyme disease
- Q fever
- Pneumonia
- Rheumatic fever
- Staphs
- Streps
- Mycoplasma
- Legionella
What are the autoimmune causes of pericarditis?
- SLE
- RA
- Vasculitides
- IBD
- Sarcoidosis
- Amyloidosis
- Dressler’s
What drugs can cause pericarditis?
- Procainamide
- Hydralazine
- Penicillin
- Isoniazid
- Chemotherapy
What are the metabolic causes of pericarditis?
- Anorexia nervosa
- Hypothyroidism
- Uraemia
What are the signs and symptoms of pericarditis?
- Central chest pain, worse on inspiration or lying flat
- Fever
- Pericardial friction rub
- Evidence of pericardial effusion or tamponade
What investigations are involved in the diagnosis of pericarditis?
- ECG
- Blood tests
- Chest x-ray
- Echo if suspected pericardial effusion
What does the ECG show in pericarditis?
Classically shows concave (saddle-shaped) ST segment elevation and PR depresion, but may be normal or non-specific
Which pericarditis patients can be managed in an outpatient setting, without the need for hospital
Stable patients
What is involvement in the outpatient management of pericarditis?
- Treatment of underlying cause
- Rest, and avoidance of any demanding physical activity
- NSAIDs
- Colchine
What NSAIDs are given first line in the outpatient management of pericarditis?
Naproxen 250mg 6-8 hourly
How long should NSAIDs be given in the outpatient management of pericarditis?
7-14 days, and then the dose should be tapered until resolution of symptoms and improvement in CRP and ESR readings