9/11- Topics in ASD: Developmental Differences Flashcards
How is the DSM-V different from the DSM-IV?
- There is no longer the Rett’s Disorder due to a genetic cause.
- All disorders such as Autism, Asperger’s, CDD, and PDD-NOS are under the general umbrella of “Autism Spectrum Disorder.”
- Therefore no more classification of Pervasive Developmental Disorder
What is the difference between High Functioning Autism and Asperger’s Syndrome?
HFA:
- Signs & symptoms are less severe
- May experience classic signs of Autism in early childhood
- Later cognitive testing reveals average to above average intelligence
Asperger’s Syndrome:
- Early language & cognitive developmental is normal
- Less likely to experience preoccupation with objects
- Less likely to experience unusual motore behaviors
Why is ASD not a localized brain disorder?
- Because it affects multiple areas & multiple networks.
- They know this through traditional MRI’s and a new procedure known as fMRI
What did the Neuroscientific studies (Geshwin, et al, 2007, Muller 2007, Rippon, et al 2007) state?
- ASD is not a localized brain disorder
- Disorder involving multiple functional networks
- Under-connectivity of the neural system
What is the Functional Magnetic Resonance Imaging (fMRI)?
- Relatively new procedure that uses a powerful magnetic field to measure & observe metabolic changes that take place in an “active” brain
- This is different from traditional MRI because the activity of the brain is recorded during cognitive or language tasks –> So researchers look for patterns of blood flow in different regions of the brain
- Diagnostic method of choice for learning how normal, diseased, or an injured brain is working.
What is the diagnostic method of choice for learning how normal, diseased, or an injured brain is working?
- fMRI
What is the goal of neuroscience?
- To use brain imaging to distinguish between Autism & other developmental disorders (with similar early symptoms)
- Also helps to distinguish between different subgroups of different types of Autism. (Example: One subgroup is a type where the brain is structurally larger caled, “macrocephaly” found sometimes among kids w/HFA)
T/F: Brain differences contribute to core deficits, core deficits cause processing and learning differences?
TRUE
What percent of children with autism do NOT have an intellectual disability?
40%
What are the 7 neurobiological findings?
- High peripheral levels of serotonin
- High rates of seizure disorder
- Persistent primitive reflexes
- Increased head size & increased brain volume
- Changes within CNS
- Fusiform gyrus & faces
- Placental abnormalities
What is Serotonin and where is it located?
- It is a neurotransmitter that egulates sleep mood & body temperature
- Located in the Central Nervous System
What percent of children with autism have normal EEG’s?
About 50%
What is the reflex known as that is in infants where a Dr. brings the hammer to the mouth & infant starts sucking?
- Visual Rooting Reflex
What percent of children have increased brain growth in infancy?
About 20%
The Changes in the CNS within the Neurological finding include Mincolumns, mirror neurons… What are these mirror neurons?
- They are a system of neurons, located in the pre-motor cortex. Relevant part of the brain for planning, execution, & selection of actions.
- This part of the brain is activated when your making a facial gesture, its the same part of the brain that is working when you’re observing other facial expression.
- Mirror Neurons help facilitate & translate the emotions of others.
