8. Muscles Flashcards
- Which muscle naming criteria are used to name the quadriceps femoris?
A. Muscle action and location
B. The origin and insertion
C. Location and direction of muscle fibres
D. Location and number of origins
Answer is D: Femoris refers to location on the femur; quadriceps refers to four origins.
- By what name is the plasma membrane of a muscle cell known?
A. Sarcoplasm
B. Sarcomere
C. Sarcoplasmic reticulum
D. Sarcolemma
Answer is D: “Sarco-” refers to flesh (muscle); “lemma-” refers to sheath (membrane) around the cell.
- Of the events that lead to myofilaments sliding over each other, which of the following happens first?
A. The myosin head engages with the binding site on actin.
B. Troponin changes shape and pulls on tropomyosin.
C. Calcium ions enter the cell cytoplasm.
D. ATP is hydrolysed to ADP and inorganic phosphate.
Answer is C: Ca must first enter the cytoplasm in order to bind with troponin. Once the binding site is exposed, the myosin head may engage the site. Prior to engagement, ATP must be hydrolysed to ADP.
- Smooth muscle is different from skeletal muscle because smooth muscle:
A. Is found in the walls of arteries
B. Can be voluntarily contracted
C. Has many nuclei in a cell
D. Has intercalated discs between cells
Answer is A: Smooth muscle occurs in the walls of tubes, whereas skeletal muscle does not.
- Which of the following muscles is named according to its origin and insertion?
A. Transversus abdominis
B. Semimembranosus
C. Sternocleidomastoid D. Deltoid
Answer is C: The origin is on the sternum and clavicle (sternocleido-), while the insertion (on the “moving bone”) is to the mastoid process of the temporal bone.
- All of the following structures are part of a muscle cell except one. Which one?
A. Sarcoma
B. Sarcolemma
C. Sarcoplasm
D. Sarcoplasmic reticulum
Answer is A: Sarcoma refers to a malignant tumour (a cancer) of connective or other non-epithelial tissue (bones, muscles, tendons, cartilage, nerves, fat and blood vessels).
- During muscle cell contraction, what happens because of Ca++ binding to troponin?
A. The binding site on actin is uncovered.
B. Acetylcholine (ACh) is released.
C. The cross-bridge disengages from the thin filament.
D. ATP hydrolyses to ADP.
Answer is A: Troponin causes tropomyosin (which covers the binding site of actin) to be shifted away.
- Which of the following muscle cell structures is the longest?
A. A myofilament
B. A myofibril
C. A sarcomere
D. A troponin molecule
Answer is B: A muscle cell is a bundle of myofibrils. Myofibrils contain many sarcomeres joined end to end. Within sarcomeres are found (the shorter) thick and thin myofilaments.
- Which of the muscles listed below is named according to its action?
A. Adductor longus
B. Temporalis
C. Sternocleidomastoid D. Peroneus longus
Answer is A: Adduction is the action of bringing an abducted bone back towards the body’s midline.
- Which of the following is the smallest structure within a muscle fibre?
A. Myosin
B. Myofilament
C. Myofibril
D. Sarcomere
Answer is A: Myosin is a molecule that makes up a thick myofilament. Many thick and thin myofilaments make up a sarcomere. Many sarcomeres joined end to end form a myofibril.
- Which of the events below is the FIRST to occur prior to a muscle cell contracting?
A. ATP binds to myosin.
B. ADP detaches from myosin.
C. The active site on actin is exposed.
D. Ca++ is released from the sarcoplasmic reticulum.
Answer is D: The release of Ca from where it is stored (in the SR) is necessary before the active binding site of actin can be exposed.
- What is a “sarcomere”?
A. A cancer of connective tissue
B. The cytoplasm of a muscle cell
C. A section of a myofilament
D. The plasma membrane of a muscle cell
Answer is C: A myofilament is a long line of sarcomeres joined end to end. So one section of a myofilament is a sarcomere.
- Smooth muscle cells may be described by which of the following?
A. Striated, voluntary, multinucleate
B. Not striated, voluntary, multinucleate C. Striated, involuntary, uninucleate
D. Not striated, involuntary, uninucleate
Answer is D: Smooth muscle is not striated, and it is involuntary and has one nucleus.
- By which term is a muscle that opposes or reverses a particular movement called?
A. Agonist
B. Synergist
C. Antagonist
D. Fixator
Answer is C: An agonist muscle performs the action, while the antagonist must relax (be stretched) while the action is being performed (and can reverse the action of the agonist).
- Which term is given to the unit of a myofibril that contracts?
A. Sarcoplasm
B. Sarcomere
C. Sarcolemma
D. Sarcoplasmic reticulum
Answer is B: The contraction of a myofibril is due to the shortening of its component sarcomeres.
- Which is the largest of the structures in a muscle fibre?
A. Myofibril
B. Myofilament
C. Myosin
D. Myopic
Answer is A: A myofibril extends the length of a muscle cell. A myofilament is shorter than a sarcomere, while myosin is a molecule in a thick myofilament.
- Where are the semimembranosus and semitendinosus muscles located? In the:
A. Seminal vesicle
B. Thigh
C. Forearm
D. Back
Answer is B: They are two of the three “hamstring” muscles on the dorsal thigh, the other being the biceps femoris.
- By what name is something that attaches a bone to another bone known?
A. Aponeurosis
B. Sarcomere
C. Ligament
D. Tendon
Answer is C: Ligament is the “ligature” that joins articulating bones. A tendon (or an aponeurosis) attaches a muscle to a bone.
- Which protein(s) are found in thin myofilaments?
A. Actin
B. Actin and tropomyosin
C. Actin, tropomyosin and troponin
D. Actin, myosin, tropomyosin and troponin
Answer is C: Actin is the major component of a thin filament. Tropomyosin covers the biding site, while troponin provides the mechanism for removing tropomyosin from the binding site.
- Which statement below best describes the role of Ca++ in muscle contraction?
A. Ca++ binds to troponin, thereby changing its shape to expose the binding site.
B. Ca++ causes ADP and inorganic phosphate to detach from the myosin cross-bridge.
C. Ca++ attaches to the myosin head, causing it to disengage from its binding site.
D. Ca++ crosses the sarcolemma from the axon terminal which allows the action potential to propagate along the sarcolemma
Answer is A: Ca attaches to troponin causing a shape change which shifts the
attached tropomyosin away from binding sites of actin.
- What characteristic of a smooth muscle cell distinguishes it from cardiac and from skeletal muscle?
A. Being branched
B. Being under involuntary control
C. Lack of striations
D. Being uninucleate
Answer is C: Both cardiac and skeletal muscle show striations when viewed under the microscope, but smooth muscle does not.
- What information is contained in the muscle name “biceps brachii”?
A. The muscle location and the number of origins
B. The number of origins and the muscle action
C. The muscle size and location in the body
D. The muscle’s shape and its action
Answer is A: “Brachii” indicates location on the brachium (arm), while “biceps” refers to the two origins (attachments) of the muscle.
- Which of the following muscles is a common intramuscular injection site?
A. Deltoid
B. Gluteus maximus
C. Vastus medialis
D. Latissimus dorsi
Answer is A: The upper arm at the shoulder is the location of the deltoid. It is the gluteus medius (rather than the gluteus maximus) that is used for IM injections to avoid the sciatic nerve.
- What causes the myosin binding site of an actin molecule to be exposed?
A. ATP attaching to the myosin cross-bridge
B. A nerve impulse reaching the motor end plate of a motor nerve
C. Calcium ions attaching to troponin
D. Acetylcholine crossing the neuromuscular junction
Answer is C: Ca causes a change of shape to the troponin molecule when they attach. This causes troponin to wrench tropomyosin away from its resting position covering the binding site.
- What is the source of the majority of the energy needed by muscles for physical activity that continues for longer than 30 or 40 min?
A. ATP stored in muscle fibres
B. Glycolysis of glucose in the cell cytoplasm
C. ATP produced from creatine phosphate stored in muscle fibres D. Aerobic respiration of pyruvic acid in mitochondria
Answer is D: Choice A lasts for a few seconds only. Choice B can provide energy for a couple of minutes. Choice C can provide energy for vigorous activity lasting about 15 s.
- Which one of the following is NOT a characteristic of skeletal muscle?
A. Excitability
B. Autonomic innervation
C. Contractility
D. Extensibility
Answer is B: Skeletal muscle is voluntary and so is innervated by the somatic nervous system, not the autonomic system.
- What is the gluteus maximus named for? Its:
A. Size
B. Shape
C. Action
D. Origin and insertion
Answer is A: The gluteus maximus is larger than either the gluteus medius or gluteus minimus.
- Which of the following muscles is NOT named after its location in the body?
A. Deltoid
B. Extensor carpi ulnaris C. Rectus abdominis
D. Biceps femoris
Answer is A: The deltoid is named after its shape, which is likened to the capital Greek letter delta (a triangle).
- Skeletal muscle cells have all of the following characteristics EXCEPT one. Which one?
A. A neuromuscular junction crossed by ACh (acetyl choline)
B. Invaginations of sarcolemma called “T tubules”
C. They are branched
D. They are striated
Answer is C: Skeletal muscle cells are not branched (but cardiac muscle cells are).
- What is the role of Ca++ in muscle contraction?
A. Ca causes an action potential to travel along the sarcolemma.
B. Ca binds to troponin changing its shape.
C. Ca attaches to the binding site of myosin, energising it.
D. Ca engages with the binding site of actin causing the power stroke.
Answer is B: The myosin head cannot attach to actin until its binding site is exposed. Ca causes this to happen.
Which of the following muscle structures is the largest?
A. Sarcomere B. Fascicle
C. Myofibril
D. Muscle fibre
Answer is B: A muscle fascicle is a bundle of muscle fibres (cells). Choice A and B are smaller than a cell.
- Which of the following muscles is NOT named after its location in the body?
A. Biceps brachii
B. Sternocleidomastoid C. Rectus abdominis
D. Flexor carpi radialis
Answer is B: The sternocleidomastoid is named after its origins (on the sternum and clavicle) and insertion (the mastoid process).
- Which feature is shared by cardiac muscle cells and skeletal muscle cells?
A. Striations
B. Intercalated discs
C. Branching
D. Involuntary nature
Answer is A: Both types of muscle cells are striated. Choices B, C and D are characteristics of cardiac muscle cells only.
- What structures attach a muscle to a bone?
A. A tendon
B. A fasciculus
C. A sarcomere
D. An internal intercostal
Answer is A: Tendons (thin ropelike structures) attach muscle to bone.
- What is the substance that binds to troponin in order to cause muscle contraction?
A. PO4 2−
B. H3O+
C. Ca++
D. Fe++
Answer is C: Calcium ions do the job.
- Which of the following muscles is NOT named after its location in the body?
A. Latissimus dorsi
B. Adductor longus
C. Rectus femoris
D. Biceps brachii
Answer is B: “Adductor” refers to the action of adduction, while longus refers to its size. Latissimus dorsi refers to the dorsal surface of the body.
- Which of the following muscle structures is the smallest?
A. Sarcomere
B. Fasciculus
C. Myofibril
D. Muscle fibre
Answer is A: A sarcomere is a section of a myofibril. A muscle fibre (cell) is a bundle of myofibrils, while a fasciculus is a bundle of muscle fibres.
- A feature of skeletal muscle that is NOT shared with cardiac or smooth muscle is:
A. Striations
B. Branched cells
C. Intercalated discs
D. Many nuclei
Answer is D: A skeletal muscle cell is a “syncytium” being derived from many cells and so retains their many nuclei.
- Which muscles extend the leg?
A. Quadriceps
B. Hamstrings
C. Gluteus muscles
D. Soleus, gastrocnemius and tibialis anterior
Answer is A: Anatomically “leg” refers to the limb between the knee and ankle. Extension of the leg is achieved by contacting the quadriceps (on the front of the thigh).
- What is the role of acetylcholine in muscle cell contraction?
A. It is a neurotransmitter.
B. It binds to troponin causing it to change shape.
C. It supplies the energy for contraction.
D. It engages with the binding site on actin.
Answer is A: ACh crosses the synaptic cleft to transmit a neural impulse to the muscle sarcolemma.
- What is a sarcomere?
A. It is the plasma membrane of a muscle cell.
B. It is the cytoplasm of a muscle cell.
C. It is a section of myofibril.
D. It is a bundle of thick and thin myofilaments.
Answer is C: While there are thick and thin myofibrils within a sarcomere, choice C is the better answer.