8 - Malignant disease Flashcards
1
Q
Tacrolimous and cicloporin are both ……
name a significant sideeffect of each
A
calcineurin inhibitors - for preventing transplant rejection MAINTAIN BRAND
ciclopsorin - nephrotoxic & skin conditions
tacrolimus - glucose metabolism disturbance
2
Q
some risks of MABs (antilymphocyte) 3
A
cytokine release - tumour lysis syndrome
and infustion related reactions
progressive multifocal leucoencephalopathy
3
Q
what mab is associated with oesteonecrosis of the jaw
A
bevacizumab
4
Q
what mab is assiciated with kerititis and ulcerative kerititis
A
cetuximab (this acts on epidermal GROWTH factor)
5
Q
mab for EDFR in non mutated RAS cancers associated with warnings about
- severe skin reactions
- keritits and ulcerative keritis
A
panitumumab
