8 - Gynecological Cancer Flashcards
This cancer is often asymptomatic. They may present with pain, abdominal bloating, and early satiety/anorexia.
ovarian cancer
If a Pap smear comes back positive what diagnostic study is indicated for further evaluation for cervical cancer?
colposcopy
Lynch syndrome is associated with what gynecological cancer?
endometrial cancer
What germ cell tumor marker do we order if we are concerned for yolk sac tumors?
AFP
What is the treatment for CIN 2/3?
excisional or ablative method
most common = LEEP
What germ cell tumor marker do we order if we are concerned for choriocarcinona?
HCG
What is the observation schedule for CIN 2?
follow up with cytology and HPV testing every 6 months
What is the most deadly gynecologic malignancy?
ovarian cancer
What is the most common gynecological cancer?
endometrial
best survival of all cancers
T/F: A simple cyst less than 10cm in a pre-menopausal woman DOES NOT require additional surveillance.
True
We begin screening for HPV at what age?
21
Which of the following is diagnostic for ovarian cancer?
a. tumor markers
b. pelvic US
c. CT
d. Surgery
d. Surgery
OR paracentesis/thoracentesis
other 3 options can only suggest
Frequent, heavy, prolonged menses is consistent with this cancer.
endometrial
What diagnostic test is indicated for endometrial cancer?
endometrial biopsy
What is the main treatment for ovarian cancer?
- surgery + chemotherapy
Where is the most common site of HPV infection?
squamocolumnar junction
What 2 oncogenes are associated with HPV?
E6/E7
What is the treatment for vulvodynia?
amitriptyline
What is the surgical treatment option for endometrial cancer?
hysterectomy and bilateral salpingo-oophorectomy
What test is used to screen for HPV?
Pap smear
Excessive estrogen stimulation is associated with what gynecological cancer?
endometrial cancer
What is the medical treatment option for endometrial cancer?
progestin therapy
This virus is necessary to develop cervical cancer.
HPV
What germ cell tumor marker do we order if we are concerned for mixed tumors?
CA-125
BRCA genes are associated with what cancer?
ovarian cancer
What 2 types of HPV cause 70% of cervical dysplasia and cancer?
- HPV 16/18
How is uterine cancer staged?
surgically
What is the treatment for late cervical cancer?
brachytherapy (radiation)
what is the observation schedule for CIN 1?
follow up with cytology and HPV testing in 12 months
What classifies a complex atypical hyperplasia?
complex glands + cytological atypia (EIN)
Speed bumps along the levator ani bilaterally is the hallmark sign of what condition?
levator ani syndrome (LAS) ??
What is the treatment for early cervical cancer?
radical hysterectomy
What is the most common culprit of a ovarian torsion?
mature teratoma
Almost all of germ cell tumors are what type?
mature teratomas (dermoids)
benign
What germ cell tumor marker do we order if we are concerned for dysgerminoma?
LDH
