8 - Gynecological Cancer

Question 1

This cancer is often asymptomatic. They may present with pain, abdominal bloating, and early satiety/anorexia.

Answer 1

ovarian cancer

Question 2

If a Pap smear comes back positive what diagnostic study is indicated for further evaluation for cervical cancer?

Answer 2

colposcopy

Question 3

Lynch syndrome is associated with what gynecological cancer?

Answer 3

endometrial cancer

Question 4

What germ cell tumor marker do we order if we are concerned for yolk sac tumors?

Answer 4

AFP

Question 5

What is the treatment for CIN 2/3?

Answer 5

excisional or ablative method

most common = LEEP

Question 6

What germ cell tumor marker do we order if we are concerned for choriocarcinona?

Answer 6

HCG

Question 7

What is the observation schedule for CIN 2?

Answer 7

follow up with cytology and HPV testing every 6 months

Question 8

What is the most deadly gynecologic malignancy?

Answer 8

ovarian cancer

Question 9

What is the most common gynecological cancer?

Answer 9

endometrial

best survival of all cancers

Question 10

T/F: A simple cyst less than 10cm in a pre-menopausal woman DOES NOT require additional surveillance.

Answer 10

True

Question 11

We begin screening for HPV at what age?

Answer 11

21

Question 12

Which of the following is diagnostic for ovarian cancer?

a. tumor markers
b. pelvic US
c. CT
d. Surgery

Answer 12

d. Surgery

OR paracentesis/thoracentesis

other 3 options can only suggest

Question 13

Frequent, heavy, prolonged menses is consistent with this cancer.

Answer 13

endometrial

Question 14

What diagnostic test is indicated for endometrial cancer?

Answer 14

endometrial biopsy

Question 15

What is the main treatment for ovarian cancer?

Answer 15

• surgery + chemotherapy

Question 16

Where is the most common site of HPV infection?

Answer 16

squamocolumnar junction

Question 17

What 2 oncogenes are associated with HPV?

Answer 17

E6/E7

Question 18

What is the treatment for vulvodynia?

Answer 18

amitriptyline

Question 19

What is the surgical treatment option for endometrial cancer?

Answer 19

hysterectomy and bilateral salpingo-oophorectomy

Question 20

What test is used to screen for HPV?

Answer 20

Pap smear

Question 21

Excessive estrogen stimulation is associated with what gynecological cancer?

Answer 21

endometrial cancer

Question 22

What is the medical treatment option for endometrial cancer?

Answer 22

progestin therapy

Question 23

This virus is necessary to develop cervical cancer.

Answer 23

HPV

Question 24

What germ cell tumor marker do we order if we are concerned for mixed tumors?

Answer 24

CA-125

Question 25

BRCA genes are associated with what cancer?

Answer 25

ovarian cancer

Question 26

What 2 types of HPV cause 70% of cervical dysplasia and cancer?

Answer 26

- HPV 16/18

Question 27

How is uterine cancer staged?

Answer 27

surgically

Question 28

What is the treatment for late cervical cancer?

Answer 28

brachytherapy (radiation)

Question 29

what is the observation schedule for CIN 1?

Answer 29

follow up with cytology and HPV testing in 12 months

Question 30

What classifies a complex atypical hyperplasia?

Answer 30

complex glands + cytological atypia (EIN)

Question 31

Speed bumps along the levator ani bilaterally is the hallmark sign of what condition?

Answer 31

levator ani syndrome (LAS) ??

Question 32

What is the treatment for early cervical cancer?

Answer 32

radical hysterectomy

Question 33

What is the most common culprit of a ovarian torsion?

Answer 33

mature teratoma

Question 34

Almost all of germ cell tumors are what type?

Answer 34

mature teratomas (dermoids) *benign*

Question 35

What germ cell tumor marker do we order if we are concerned for dysgerminoma?

Answer 35

LDH