8. Benign tumours of the female breast Flashcards
Benign tumours of the female breast
- Duct papilloma
* Fibroadenoma
Duct papilloma In Benign tumours of the female breast
- Etiology
- Pathology
- Clinical Picture
- Investigations
- Treatment
Etiology of Duct papilloma In Benign tumours of the female breast
- Benign tumour arising from the columnar epithelium of the ducts
- Excessive localization of epitheliosis of ANDI
Pathology of Duct papilloma In Benign tumours of the female breast
- Cell of origin
- Composition
- Ulceration
- Blocking the duct
Cell of origin in Pathology of Duct papilloma In Benign tumours of the female breast
arises in one of the main ducts near the nipple in a Young woman
Composition in Pathology of Duct papilloma In Benign tumours of the female breast
composed of vascular C.T Core Covered by hyperplastic columnar epithelium
Ulceration in Pathology of Duct papilloma In Benign tumours of the female breast
- Before it becomes big enough to form a palpable lump, it usually ulcerates
- Causes bleeding per nipple
Blocking the duct in Pathology of Duct papilloma In Benign tumours of the female breast
causes a retention cyst.
Clinical Picture of Duct papilloma In Benign tumours of the female breast
- Bleeding per nipple
2. Retroareolar retention cyst may be felt
Pathogenesis of Retroareolar retention cyst in Clinical Picture of Duct papilloma In Benign tumours of the female breast
due to obstruction of the duct
Investigations of Duct papilloma In Benign tumours of the female breast
- Differential pressure
- Ductography
- Cytology For the discharge
- Mammography & complementary breast U/S :
Benefits of Differential pressure in Investigations of Duct papilloma In Benign tumours of the female breast
To localize the papilloma
Finding of Ductography in Investigations of Duct papilloma In Benign tumours of the female breast
Shows the lesion as a filling defect
Benefits of Mammography & complementary breast U/S in Investigations of Duct papilloma In Benign tumours of the female breast
to detect non palpable lump.
Treatment of Duct papilloma In Benign tumours of the female breast
Microdochectomy
Microdochectomy in Treatment of Duct papilloma In Benign tumours of the female breast
- Excision of the affected duct in duct papilloma
* The duct is identified at operation by passing a blunt tipped needle through the discharging nipple opening
Fibroadenoma In Benign tumours of the female breast
- Incidence
- Etiology
- Pathology
- Clinical picture
- Differential Diagnosis
- Investigations
- Treatment
Incidence of Fibroadenoma In Benign tumours of the female breast
The commonest benign breast mass of females
Etiology of Fibroadenoma In Benign tumours of the female breast
- Benign tumour arising from both fibrous & glandular elements.
- Excessive localization of fibrosis & adenosis of ANDI
Pathology of Fibroadenoma In Benign tumours of the female breast
There are two types:
- Pericanalicular fibroadenoma
- Intracanalicular fibroadenoma
Pericanalicular fibroadenoma in Pathology of Fibroadenoma In Benign tumours of the female breast
- Alternative name
* Composition
Alternative names for Pericanalicular fibroadenoma in Pathology of Fibroadenoma In Benign tumours of the female breast
Hard fibroadenoma
breast mouse because it’s mobile all over
Composition of Pericanalicular fibroadenoma in Pathology of Fibroadenoma In Benign tumours of the female breast
- These tumours are formed mainly of fibrous tissue & Iess glandular element
- They tend to be small.
Intracanalicular fibroadenoma in Pathology of Fibroadenoma In Benign tumours of the female breast
- Alternative name
* Composition
Alternative name for Intracanalicular fibroadenoma in Pathology of Fibroadenoma In Benign tumours of the female breast
Soft fibroadenoma
Composition of Intracanalicular fibroadenoma in Pathology of Fibroadenoma In Benign tumours of the female breast
Contains more glandular element than fibrous tissue .
The markedly dilated acini
They are usually larger and softer than the pericanalicular type.
The markedly dilated acini in Composition of Intracanalicular fibroadenoma in Pathology of Fibroadenoma In Benign tumours of the female breast
showing projections inside
The fibrous tissue is loosely arranged around them (hence the false name intracanalicular).
Clinical Picture of Fibroadenoma In Benign tumours of the female breast
- Symptoms
- Examination
- Other clinical variants for soft fibroadenoma
Symptoms in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
- Accidentally discovered painless lump
- Age of presentation in Hard fibroadenoma
- Age of presentation in soft fibroadenoma
Age of presentation in Hard fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
commonly in young women 20-30 years of age
Age of presentation in soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
between the ages of 30-50 years.
Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
a. Breast :
b. Axillary L.N.:
Breast Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Mass with the following criteria :
- Size
- Shape
- Surface
- Mobility
- Edge
- Consistency
Size of the breast Mass in Breast Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
- Small in hard fibroadenoma
* large in soft fibroadenoma.
Shape of the breast Mass in Breast Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Spherical
Surface of the breast Mass in Breast Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Smooth in hard fibroadenoma
lobulated in soft fibroadenoma.
Mobility of the breast Mass in Breast Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Mobile all over ( hard fibroadenoma is called breast mouse).
Edge of the breast Mass in Breast Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Well circumscribed.
Consistency of the breast Mass in Breast Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
- Firm in pericanalicular ( hard ) fibroadenoma
* soft in intracanalicular ( soft ) fibroadenoma.
Axillary L.N Examination in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Not enlarged
Other clinical variants for soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
- Giant fibroadenoma
2. Cystosarcoma phylloides “serocystic disease of Brodie”.
Age of presentation of Giant fibroadenoma in Other clinical variants for soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Occur during puberty
Cystosarcoma phylloides in Other clinical variants for soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
- Alternative name
- The reason why it’s called so
- Pathology
- Differential diagnosis
Alternative name for Cystosarcoma phylloides in Other clinical variants for soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
serocystic disease of Brodie
The reason why it’s calledCystosarcoma phylloides “serocystic disease of Brodie” in Other clinical variants for soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
lt was so named by Brodie who used the term phylloides
because the cut surface resembles a leaf of fern.
the term cystosarcoma is misnomer as many are not cystic and it’s not malignant
Pathology of Cystosarcoma phylloides in Other clinical variants for soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
- This is highly cellular type of fibroadenoma that grows rapidly
- The tumour tends to enlarge and to reach a large size, 20-30 cm in diameter
- causing pressure necrosis of the overlying skin without infiltrating it & the tumour fungates from it.
Differential diagnosis of Cystosarcoma phylloides in Other clinical variants for soft fibroadenoma in Clinical Picture of Fibroadenoma In Benign tumours of the female breast
Fungating carcinoma
to differentiate between cystosarcoma phylloides and fungating carcinoma do :
Probe test
positive in cystosarcoma phylloides
Differential diagnosis of Soft Fibroadenoma In Benign tumours of the female breast
medullary breast carcinoma
Investigations of Fibroadenoma In Benign tumours of the female breast
- The clinical features are usually enough for diagnosis of hard fibroadenoma.
- however triple assessment is done in both types.
Treatment of Fibroadenoma In Benign tumours of the female breast
Treatment of :
Hard fibroadenoma
Soft fibroadenoma
Giant fibroadenoma
cystosarcoma phylloides
Treatment of hard fibroadenoma in Treatment of Fibroadenoma In Benign tumours of the female breast
- Excision via a circumareolar incision.
* sent for histopathology
Treatment of soft fibroadenoma in Treatment of Fibroadenoma In Benign tumours of the female breast
- Excision
* sent for histopathology
treatment of Giant fibroadenoma in Treatment of Fibroadenoma In Benign tumours of the female breast
- Gillard thomas incision
* sent for histopathology.
Gillard thomas incision in treatment of Giant fibroadenoma in Treatment of Fibroadenoma In Benign tumours of the female breast
Wide local excision via a submammary incision to treat Giant fibroadenoma
Treatment of cystosarcoma phylloides in Treatment of Fibroadenoma In Benign tumours of the female breast
a. If not huge: Wide local excision and sent for histopathology.
b. If very huge or fungating: Simple mastectomy.
Mondor’s disease
It is thrombophlebitis of the superficial veins of the breast and anterior chest wall of unknown cause.