8/20/16

Question 1

What are the breast cancer screening recommendations (from the American Cancer Society expert panel) for pts w/ Hx of mantle radiation or BRCA mutation?

Answer 1

Annual mammogram + breast MRI

Question 2

What is the first-line treatment for painful diabetic neuropathy?

Answer 2

TCA (e.g. desipramine or amitryptyline)

Question 3

Which patients are candidates for ranolazine therapy?

Answer 3

Those w/ angina despite optimal medical Tx w/ β-blockers, CCBs, and nitrates

Question 4

What is the mechanism by which ranolazine relaxes the myocardium and reduces oxygen demand?

Answer 4

inhibits the late inward sodium current thereby decreasing intracellular calcium

Question 5

Which sex steroid increases the risk of venous thrombosis?

Answer 5

Estrogen!

Question 6

What is the typical microscopic appearance of Yersinia pestis?

Answer 6

bipolar staining Gram-negative bacillus (safety pin)

Question 7

differential for middle mediastinal mass

Answer 7

bronchogenic cyst, pericardial cyst, or lymphadenopathy

Question 8

differential for posterior mediastinal mass

Answer 8

neural tissue or esophageal tissue/cysts

Question 9

2 pathognomonic characteristics of Plasmodium falciparum on Giemsa-stained blood smear

Answer 9

rings forms at the PERIPHERY of the RBC and “banana-shaped” gametocytes

Question 10

broad-based budding yeast

Answer 10

Blastomyces

Question 11

What is the treatment for non-life-threatening blastomycosis?

Answer 11

itraconazole

Question 12

What is the treatment for severe pulmonary, CNS, or disseminated blastomycosis?

Answer 12

amphotericin B