8,11 Flashcards

1
Q

Why can two different cell types with the same DNA be so different?

A

Different cell types express different genes, leading to the production of different proteins, which define the cells’ structure and function.

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2
Q

How is gene expression regulated in cells?

A

Gene expression can be controlled at multiple levels, including transcription initiation, RNA processing, mRNA export from the nucleus, mRNA stability, translation, and protein activity.

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3
Q

What is the function of the promoter region in gene expression?

A

The promoter contains sequences where RNA polymerase binds to initiate transcription.

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4
Q

How do regulatory proteins control transcription?

A

Regulatory proteins bind to specific DNA sequences (regulatory sequences) to switch genes on or off by interacting with RNA polymerase.

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5
Q

What is an operon in bacteria?

A

An operon is a set of genes transcribed into a single mRNA molecule and controlled by a single promoter.

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6
Q

How does the lac operon function?

A

The lac operon is controlled by an activator (CAP) and a repressor. When glucose levels are low, CAP binds and helps RNA polymerase initiate transcription if lactose is present to remove the repressor.

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7
Q

What are transcription factors in eukaryotes?

A

Transcription factors are proteins that assemble on promoters to help RNA polymerase initiate transcription.

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8
Q

What is the role of the TATA box in eukaryotic transcription?

A

The TATA box is a DNA sequence that helps position RNA polymerase and transcription factors at the correct site to start transcription.

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9
Q

How do glucocorticoid hormones influence gene expression?

A

Glucocorticoid hormones bind to receptors, which then bind to DNA and activate genes involved in glucose production, particularly during starvation or stress.

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10
Q

What is a key difference between transcription in bacteria and eukaryotes?

A

In eukaryotes, transcription requires multiple transcription factors, whereas bacterial RNA polymerase can initiate transcription on its own.

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11
Q

What is the main function of the plasma membrane?

A

The plasma membrane acts as a selective barrier, allowing the passage of nutrients and waste and containing proteins that sense environmental signals.

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12
Q

What are endocytosis and exocytosis?

A

Endocytosis is the process of importing materials into the cell, while exocytosis is the export of materials out of the cell.

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13
Q

What is the basic structure of the plasma membrane?

A

The plasma membrane consists of a lipid bilayer, composed mainly of phospholipids with hydrophilic heads and hydrophobic tails.

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14
Q

What is the role of cholesterol in the plasma membrane?

A

Cholesterol helps modulate membrane fluidity and stability by filling gaps between phospholipids.

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15
Q

What factors affect membrane fluidity?

A

Membrane fluidity is affected by the length of the hydrocarbon tails, the degree of unsaturation (double bonds), and the presence of cholesterol.

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16
Q

How does cholesterol affect membrane fluidity?

A

Cholesterol reduces fluidity by filling spaces between phospholipids and making the membrane more stable.

17
Q

What are the main functions of membrane proteins?

A

Membrane proteins function as transporters, anchors, receptors, and enzymes.

18
Q

How do transmembrane proteins interact with the lipid bilayer?

A

Transmembrane proteins span the lipid bilayer, with hydrophobic regions interacting with the tails of phospholipids and hydrophilic regions interacting with the cytosol and extracellular space.

19
Q

What is the cell cortex?

A

The cell cortex is a protein framework that reinforces the plasma membrane. In red blood cells, the protein spectrin forms a meshwork that provides structural support.

20
Q

What is the function of glycoproteins and glycolipids on the cell surface?

A

Glycoproteins and glycolipids are involved in cell recognition, protection, and providing a slimy surface to help cells move and prevent them from sticking together.

21
Q

How do carbohydrates help immune cells like neutrophils recognize infection sites?

A

Carbohydrates on neutrophils bind to lectin proteins on endothelial cells at infection sites, guiding the neutrophils to the site of infection.