7.3 - Dysmenorrhoea + Endometriosis Flashcards

1
Q

Define primary and secondary dysmenorrhoea

A

Primary: Pain associated with the menstrual cycle and begins with onset of ovulatory cycles typically at menarche +/- 2yrs. (as in was always painful)

Secondary: Pain associated with the menstrual cycle due to pelvic pathology (was not painful and now painful).

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2
Q

How would you manage a patient with primary dysmenorrhoea (notice manage and not just treatment of)!

A

Conduct abdominal/pelvic/transvaginal US and reassure patient.

First line: NSAIDS (Mefenamic acid)
2nd Line: COCP (suppresses ovulation)
3rd line Depot progestogens (Suppresses ovulation and reduces contractions)
4th line: Mirena Coil (LVN-IUS)
When I say lines here, any would work, it is based on the preference of the patient

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3
Q

Why do you conduct an US with a patient presenting with dysmenorrhea since the age of 12. Note: Menarche was at age 13 and the patient is currently 14 years old.

A

This is a case of !primary dysmenorrhea. In these cases, the abdominal/pelvic/transvaginal US is used to ensure that there are no pelvic pathologies that may be causing this and reassure the patient

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4
Q

Secondary is defined as pain associated with the menstrual cycle due to pelvic pathology. Give 4 pelvic pathologies

A

Fibroids
Adenomyosis
Endometriosis
PID

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5
Q

How would you manage a patient with secondary dysmenorrhoea (notice manage and not just treatment of)!

A

Perform a history and clinical exam including a pelvic exam

If is normal, begin with medications (NSAIDs, COCP, Depot progestogen, Mirena Coil)

If abnormal findings (e.g. Pelvic mass/tenderness) or medications have failed, US/Diagnostic laparoscopy
Why not hysteroscopy? Its not completely wrong, but in the absence of heavy menstrual bleeding, the pelvic pathologies are typically out of the uterus

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6
Q

A patient with dysmenorrhea on the ward asks for pain killers. she says she typically uses codeine for this pain. Why would you not prescribe codeine?

A

Constipation => increased abdominal pressure => more pain

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7
Q

What is adenomyosis?

A

Endometrial-like tissue in the myometrium (muscles of the uterus)

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8
Q

10% of women are affected by endometriosis. Define Endometriosis

A

The presence of !Oestrogen-dependent, endometrial-like tissue outside the uterus !with impact on quality of life.

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9
Q

What are the 2 main culprits of PID (pelvic inflammatory disease)?

A

Chlamydia, Gonorrhoea

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10
Q

Give 6 sx of Endometriosis

A

Must include:
Chronic pelvic pain
Dysmenorrhea
Subfertility.
Dyspareunia
Rectovaginal disease

Others: Ovulation pain, Chronic fatigue, may affect bladder.

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11
Q

What is the Retrograde menstruation theory?

A

It is the theory explaining the ethology of endometriosis.

The retrograde menstrual theory of endometriosis suggests that during menstruation, some of the menstrual blood flows backwards through the fallopian tubes into the pelvic cavity instead of leaving the body. This backward flow can carry endometrial cells (the cells lining the uterus) with it, which then implant and grow on organs within the pelvic area, such as the ovaries and fallopian tubes. This process can lead to the development of endometriosis, causing pain, inflammation, and sometimes infertility.

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12
Q

Based on the theory of retrograde menstruation, pelvic sites are most commonly affected. State 5 pelvic and 2 extrapelvic sites

A

Pelvic: Broad ligamentm Round ligament, cervix, rectum, sigmoid colon,

Extrapelvic: Umbilicus, Lungs, scars from laparotomy/perineal scars.

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13
Q

You are taking a history from a patient suffering from dysmenorrhea. What questions would you ask?

A

Relationship of pain to cycle -> !SOCRATES
Offer pain relief
Endometriosis: Dyspareunia, Dyschezia
PID: Fever, previous UTI
Impact on quality of life (part of definition)
Always! Previous investigations and treatment to date.
Always! Desire for future fertility

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14
Q

You are about to perform an examination on a patient presenting with dysmenorrhoea. What examination findings are you looking for?

A

Fixed, retroverted uterus
Pelvic tenderness (Uterosacral ligaments)
Palpable nodules (in pouch of douglas or uterosacral ligaments)

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15
Q

You have taken a history and a focused examination noting pelvic tenderness. You opt to perform a diagnostic laparoscopy as previous medications have failed. What findings would indicate endometriosis? State 4

A

“Powder Burn” lesions (1st pic)
“Gunshot lesions” second pic
Red implants (third picture)
Endometriomas/chocolate cysts, Kissing ovaries (4th picture)
Nodules and cysts (broad/uterosacral ligaments)

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16
Q

State your full management plan for endometriosis

A

Conservative (2): Hot water bottle
TENS - Transcutaneous electric nerve stimulation (device on lower back for pain)
Vit. B1

Medical: 1st Analgesia, 2nd Suppression of ovarian function
Progestogens whether oral via medroxyprogesterone or Levonorgestrel IUS)
COCP
GnRH analogue (Decapeptyl)

Surgical:
1st line: Laparoscopic superficial lesion ablation or deep lesion excision.
2nd Line: Total Abdominal Hysterectomy +Bilateral Salpingo-oophorectomy.
Both with post-op hormonal treatment to reduce recurrence

17
Q

Why is excision regarded as superior to ablation in the case of endometriosis?

A

Excision allows a sample to be send for histology

18
Q

A patient is presenting with chronic pelvic pain. Give 10 ddx

A

Gynaecological: Endometriosis, Adenomyosis, Ovarian cysts, Ovarian malignancy, Adhesions, Chronic PID

Urological: Interstitial cystitis, Bladder diverticulitis, chronic urolithiases

GIT: IBS, IBD

MSK: Pelvic floor dysfunction

Psych: Functional disorder