7.2.2 Issues In Systematic Reviews And Meta-analyses Flashcards
1
Q
What are some issues with meta analysis?
A
Heterogeneity between studies
Variable quality of the studies
Publication bias in selection of studies
2
Q
What is heterogeneity between studies?
A
Observed effects in studies are more different than we would expect by chance
3
Q
What causes heterogeneity between studies?
A
Differences in methods
Methodological heterogeneity
Differences in patients, interventions and outcomes
Clinical heterogeneity
4
Q
What can we do about heterogeneity between studies?
A
Should not pool studies that have a different measurement
Fixed effect model- assumes that studies are estimating exactly the same true effect size
Random effects model- incorporates heterogeneity by assuming that studies are estimating similar true effect size
5
Q
Slide 37+
A
