7.19 Gastrointestinal Protozoans Flashcards
Causative agent for amebiasis
Entamoeba histolytica
Natural hosts of E. histolytica
Primates
Most common manifestations of invasive amebiasis
Amebic colitis
Most common manifestation of extra-intestinal invasive amebiasis
Amebic liver abscess
Infective stage of E. histolytica
Ingestion of the cystic form
Excystation of E. histolytica occurs in
Terminal ileum
Mediates the adherence stage of trophozoites to colonic epithelial cells
Galactose/N-acteylgalactosamine specific lectin
Molecules seen on trophozoites, conferring protection form MAC
CD59/protectin-like
Peptides capable of forming pores in lipid bilayers
Amebapores
Directly implicated in invasion and inflammation of the gut
May amplify IL-1
Cysteine proteases
Most common metastatic complication of amebiasis
Anchovy sauce
Amebic liver abscess
2nd common site of amebiasis (direct, hematogenous)
Lung
Amebiasis second only to _____ in terms of protozoa-associated mortality
Malaria
E. histolytica can be differentiated from E. dispar by:
Isoenzyme analysis
Restriction fragment polymorphism
Monoclonal Abs
Overdiagnosis of E. histolytica due to sharing common morphological characteristics with the following
E. dispar E. coli E. hartmanii Endolimax nana Iodameba buetschlii
