7.1 Pharmacokinetics

Question 1

What is pharmacokinetics?

Answer 1

What body does to drugs

1. Drug administration
2. Drug absorption
3. Drug distribution
4. Drug metabolism
5. Drug elimination

Question 2

Two forms of drug administration?

Answer 2

1. Enteral - delivery into internal environment of body e.g. GI tract, Oral, Sublingual, Rectal
2. Parenteral - delivery via non-oral means but generally interpreted as intravenous, subcutaneous, intramuscular

Question 3

Oral route of drug?

Answer 3

1. Swallow
2. Little absorption in stomach as SA 1m^2
3. Drug mixes with chyme
4. Enters small intestine (main absorption) SA 30-35m^2
5. Constant GI movement and mixing presenting drug to GI epithelia

Time - 3-5 hrs