1.1 Introduction To Cell Physiology And Pharmacology

Question 1

What does MEF require in a living cell?

Answer 1

Substrate supply system
Product distribution system (extra/intra)
Waste removal system
Reliable and responsive control systems that monitor and adjust when required

Question 2

What is the aim of living systems?

Answer 2

Maintain/maximise dynamic order through regulating flow

Minimise entropy!

Question 3

How do we regulate flow to result in good health?

Answer 3

Goldilocks

Right place,right amount, right time, right environment leads to good health

Question 4

How are signalling molecules classified?

Answer 4

Endogenous - within body
Exogenous I - natural (plant based)
Exogenous II - synthetic (man made)

Question 5

What is homeostasis?

Answer 5

Maintaining optimal environment for cells to function
Intracellular process optimally takes place when extracellular environment is stable
Monitoring and adjusting of environment according to demand/disturbance

Question 6

What are the control system components?

Answer 6

Variable - system needing control producing a measurable system output (SO)
Sensor - detects SO
Set Point/comparator - SP compared to SO
Difference error signal - negative feedback signal SP-SO
Controller - generates amplified signal to bring SO back to SP
Effector - components that bring about this change

Question 7

What temperature causes hypothermia?

Answer 7

35

Question 8

What temp do you get hyperthermia?

Answer 8

38-40

Question 9

Define synergistically and antagonistically.

Answer 9

1. Various parts working together to produce enhanced results
2. Opposing