7 Special Circulations & Hemostasis Flashcards
What is it called when smooth muscle adjusts diameter of vessels to maintain blood flow?
Myogenic mechanism
What are the four main things that a myogenic mechanism accounts for?
Autoregulation
Flow decreases, vessels dilate
Flow increases, vessels constrict
Based on maintaining wall tension of vessel
What mechanism is created by metabolic by-products that act as local signals to alter flow?
Metabolic mechanism
Co2, H+, adenosine, lactate _____ blood flow by causing vasodilation
INCREase
______ hyperemia is when exercise increases metabolic activity and metabolites. Causes dilation and more flow. Opposite is true!
ACTIVE
_____hyperemia-during transient ischemia metabolites build up, excess blood flow is required to wash them out
REACTIVE
What flow is the blood flow in the coronary vessels to feed heart?
Coronary flow
Most important is METABOLIC CONTROL
Little neural control-brain wont kill Heart or brain wont get blood (savage brain)
Skeletal blood flow is most important during times of ____. K+, lactate and adenosine required.
Reactive _____ after contraction
Neural most important during rest by use of Alpha_ and Beta_
Exercise
Hyperemia
ALpha 1. Beta 2
Skin has ____ metabolic control.
____ most important for body heat regulation
Hormonal regulation by ______
Little
Neural
Histamine
(TP) Q: Increasing skeletal muscle CO2 production would ________ blood flow?
A. Increase
B. Decrease
A. Increase
Means you’re running from a saber tooth tiger.. or this class
(TP) Q: Increasing skeletal muscle CO2 production would increase blood flow. This is an example of ________ regulation.
A. Active hyperemia
B. Reactive hyperemia
A. Active hyperemia
Increases vaso metabolism
Reactive is just a loss of blood flow
Immediately after damage, vessel will _____
Constricts
Slows flow to damaged area
damage to endothelium exposes ____.
This _____ binds to Von Wikkebrand factor which binds to circulating platelets.
Bound platelets release platelet ____ molecules ADP and TXA2
______ feedback mechanism.
Platelet ___ forms over damaged area
Collagen
Collagen
Activating
POSTIVE (causes and event, blood clotting)
plug (I’m the plug, really I’m the plug)
(TP) Q: What protein is responsible for platelet plug formation?
A. Fibrin
B. TXA2
C. Von Willebrand factor
D. hemoglobin
C. Von Willebrand factor
A _____ emboli usually originates in legs (deep vein thrombosis). Get stuck in lungs, cause pulmonary embolism (pulmonary ______ and ___ sided heart failure)
Venous
Hypertension
RIGHT
