6 Capillary Filtration & Lymph Flow

Question 1

Does endothelium allow for diffusion of small solutes and water? What about protein?

Answer 1

Yas

Hell na; cells either

Question 2

Non-permeable cells cross between endothelium at pores. What route is this?

Answer 2

Paracellular

Question 3

What route makes cells diffuse across the endothelial cells if permeable?

Answer 3

Transcellular

Question 4

Which set of organs have very small pores?

Brain & eye

Kidney & Liver

Answer 4

Brain and eye!!

Kidney & Liver are VERY large. Big enough to let cells through

Question 5

What serves as “drain pipes” for interstitial fluid in the body?

Answer 5

Lymphatics

Question 6

Where does lymph ultimately drain back into in the body?

Answer 6

Subclavian Veins

Question 7

What is the process where blood plasma is filtered across the capillary membrane to make the interstitial fluid?

Answer 7

Ultrafiltration

Question 8

What four pressures make up ultrafiltration?

Answer 8

Capillary pressure
Interstitial fluid pressure

Plasma colloid osmotic pressure

Interstitial fluid colloid osmotic pressure

Question 9

What two ultrafiltration pressures are the main factors in the process?

Answer 9

Capillary pressure

Plasma colloid osmotic pressure

Question 10

What two ultrafiltration pressures account for filtration? Which two account for reabsorption?

Answer 10

Capillary pressure
Interstitial fluid osmotic pressure

Interstitial fluid pressure
Plasma colloid osmotic pressure

Question 11

(TP) Q: If hydrostatic pressures and oncotic pressures in the body is the same, why does the liver produce more interstitial fluid than the brain?

A. Liver capillaries have a reduced Kf
B. Liver capillaries have an increased Kf C. Metabolic demand of liver is greater D. Blood supply to the liver is greater

Answer 11

B. Liver capillaries have an increased Kf

Question 12

(TP) Q: Increasing which of the following would increase interstitial fluid formation (capillary filtration)

A. Tissue hydrostatic pressure
B. Kf
C. Plasma Oncotic Pressure
D. Capillary hydrostatic pressure

Answer 12

Capillary hydrostatic pressure

Question 13

What happens when you increase filtration?

Answer 13

Increases interstitial fluid formation

Question 14

What happens when you increase Pc? (tissue pressure)

Answer 14

Dilate arterioles, constrict venules, increase CVP

Question 15

Anything that DECREASES filtration is going to _______ interstitial fluid formation

Answer 15

REDUCE

Question 16

Changes to venous resistance affects filtration more than arteriolar. T/F??

Answer 16

Tru Chainz

Question 17

Diffusion of small or soluble molecules is ONLY limited by ____

Answer 17

Blood flow

Question 18

Large or insoluble molecules (like proteins) are limited by _____

Answer 18

Pore size

Diffusion limited: equilibrates slowly or not at all.

Distance to cell matters

Question 19

To increase tissue concentration of flow limited molecules you must increase ______

Answer 19

Blood flow

Question 20

To increase tissue concentration of diffusion limited molecules you must increase _____

Answer 20

Diffusion rate