7. Respiratory system Flashcards

1
Q

what type of tissue holds open the larynx and trachea

A

Hyaline cartilage

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2
Q

what tissue bridges the gap between the free ends of C-shaped cartilages in the trachea?

A

smooth muscle

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3
Q

what is present within the walls of bronchi but not bronchioles?

A

cartilage

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4
Q

where is Reinke’s space?

A

in the vocal cords

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5
Q

which cells secrete surfactant?

A

type II pneumocytes

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6
Q

what cells are phagocytes

A

alveolar macrophages

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7
Q

how many cell layers are there in the air blood barrier

A

2

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8
Q

how thick is the air-blood barrier

A

600nm

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9
Q

where are the pores of Kohn

A

alveolar walls

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10
Q

respiratory epithelium

A

lines tubular portion of the respiratory
Pseudostratified
ciliated
interspaced goblet cells

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11
Q

the nose

A

filtration, humidification, warming, olfaction
keratinising and non-keratinising squamous epithelium
respiratory epithelium
richly vascular lamina propria containing seromucinous glands

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12
Q

the nose - olfaction

A

roof of nasal cavity, extending down septum and lateral wall
Pseudostratified columnar epithelium of olfactory receptor cells with supporting sustentacular cells and basal cells
serous glands of Bowman
Non-motile cilia
olfactory receptor cells
bipolar neurones - dendrite extends to surface to become club-shaped ciliated olfactory vesicle

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13
Q

nasopharynx

A

gas transport, humidification, warming, olfaction, lined by respiratory epithelium

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14
Q

nasal sinuses

A

lower the weight of the skull, add resonance to the voice, humidify and warm inspired air, lined by respiratory epithelium

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15
Q

the larynx

A

cartilaginous box (hyaline), voice production, respiratory epithelium, loose fibrocollagenous stroma with seromucinous glands, lymphatics and blood vessels common

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16
Q

the vocal cords

A

voice production
stratified squamous epithelium overlying irregular fibrous tissue (Reinke’s space)
almost no lymphatics

17
Q

tranchea

A

respiratory epithelium
seromucinous glands in submucosa
trachealis muscle posteriorly
C-shaped (hyaline) cartilagenous rings

18
Q

clara cells

A

most numerous in terminal bronchioles
mitochondria, smooth ER, secretary granules
no cilia; vesicular cytoplasm
precise purpose is uncertain, think they produce and eliminate surfactant and oxidise inhaled toxins

19
Q

respiratory bronchioles

A
first part of distal respiratory tract 
link terminal bronchioles and alveolar ducts
cuboidal ciliated epithelium 
spirally arranged smooth muscle
no cartilage
20
Q

alveoli

A

150-400 million/lung

250 um in diameter

21
Q

type I pneumocytes

A

40% of cell population
90% of surface area
flattened cells, flattened nucleus, few organelles

22
Q

type II pneumocytes

A

60% of cell population
5-10% of surface area
rounded cells, rounded nucleus, rich in mitochondra, smooth and rough ER, spherical bodies
produce surfactant

23
Q

alveolar macrophages

A

luminal cells, also present in the interstitium
phagocytose particles including dusts and bacteria
enter lymphatics or leave via mucocilary esculator

24
Q

blood-air barrier

A

type I pneumocyte
fused basement membrane of penumocyte and capillary
vascular endothelial cell
200-800nm thick

25
Q

interstitium

A
where endothelial cells are not in direct contact with pneumocytes 
collagen and alastin fibres 
fibroblasts 
macrophages 
(pore of Kohn)
26
Q

Visceral pleura

A
flat mesothelial cells 
loose fibrocollagenous connective tissue 
irregular external elastic layer 
interstitial fibrocollagenous layer 
irregular internal elastic layer