7. Genetics, Popultions, Evolution & Ecosystems Flashcards
Define phenotype
The observable or biochemical characteristics of an organism.
It’s the result of the interaction between the expression of the genotype and the environment
Define genotype
The genetic constitution of an organism. Describes all the alleles that an organism has
What is monohybrid inheritance? give an example
the inheritance of a single gene
example: Gregor Mendel’s study of colour of pea plants
What does the law of segregation state?
Only one of each pair of alleles can be present in a single gamete
Why are actual results of genetic crosses rarely the same as the predicted results?
What should you do to have more representative results?
Statistical error
The larger the sample the more likely the actual results are to come near to matching the theoretical ones
What is dihybrid inheritance?
Give an example
The way in which 2 characters, determined by 2 different genes located on different chromosomes are inherited
example: Gregor Mendel’s investigation of two characters of a pea plant (seed shape and seed colour)
What does the law of independent assortment state?
Each member of a pair of alleles may combine randomly with either of the other pair
What is codominance and when does it occur?
both alleles are expressed in the phenotype
occurs when both alleles are equally dominant
How many pairs of chromosomes do humans have?
23
What are the sex chromosomes in humans?
X and Y
females : XX
males : XY
What is significant about the X chromosome being much longer than the Y chromosome ?
For most of the length of the X chromosome, there is no equivalent homologous portion of the Y chromosome.
Therefore the characteristics that are controlled by recessive alleles on this non-homologous portion of the X chromosome will appear more frequently in the male as there is no homologous portion on the Y chromosome that might have the dominant allele
Give an example of an X linked disorder (disorder caused by a defective gene on the x chromosome)
Haemophilia (blood clots slowly, may be slow and persistent internal bleeding)
Potentially lethal if not treated
Almost entirely confined to males in part because haemophiliac females usually died with the onset of menstruation at puberty
How is haemophilia caused ?
Recessive allele with an altered sequence of DNA nucleotide bases that therefore codes for a faulty protein with no function.
Any 2 genes that occur on the same chromosome are said to be…
LINKED
The remaining 22 chromosomes which are not sex chromosomes, are called…
AUTOSOMES
What is autosomal linkage?
The name given to the situation where 2 or more genes are carried on the same autosome
When does epistasis occur?
When the allele of one gene affects or masks the expression of another in the phenotype
Define gene pool
The sum of all the alleles of all the genes of all the individuals in a population at a given time
Define population
A group of organisms of the same species that occupies a particular space at a particular time and that can potentially interbreed
Define allelic frequency
The number of times an allele occurs within the gene pool
What assumption does the Hardy-Weinberg principle make
That the proportion of dominant and recessive alleles of any gene in a population remains the same from one generation to the next
The assumption made in the Hardy-Weinberg equation can be the case so long as which 5 conditions are met?
- No mutations arise
- The population is isolated
- There is no selection (all alleles are equally likely to be passed on)
- The population is large
- Mating within the population is random
When is the Hardy-Weinberg principle particularly useful?
when studying gene frequencies
What are the equations used in the Hardy-Weinberg principle when we are considering a gene that has 2 alleles (A and a)
Let the probability of A = p
Let the probability of a = q
p+q=1
As there are only 4 possible arrangements of the 2 alleles it follows that the probability of all four added together must also equal 1 ;
AA + Aa + aA + aa = 1
or expressed as a probability …
p2 + 2pq + q2 = 1
Genetic variation arises as a result of what 3 factors?
- mutations
- meiosis
- random fertilisation of gametes
Name environmental factors that influence variation
- temp
- rainfall
- sunlight
- soil pH
- food availability
The environmental factors that limit the population of a species are called…
selection pressures
What is included under the term ‘selection pressures’?
- predation
- competition
- disease