7) Genetics, Populations, Evolution, Ecosystems Flashcards
Gene definition
A sequence of bases on a DNA molecule that codes for a protein which results in a characteristic
Allele definition
A different version of a gene
Genotype
The genetic constitution of an organism
Phenotype definition
The expression of the genetic constitution (the genotype) and its interaction with the environment
Locus definition
The fixed position of a gene on a chromosome
Alleles of a gene are found at the same locus on each chromosome in a pair
Diploid definition
Cells that have 2 sets of chromosomes, so have 2 alleles for each gene
Dominant definition
An allele whose characteristic appears in the phenotype even when there is only 1 copy
Recessive definition
An allele whose characteristic only appears in the phenotype if 2 copies are present
When to use a dihybrid cross:
When looking at how 2 different genes are inherited at the same time
Why do you sometimes not get the expected phenotypic ratio?
Due to:
- Sex linkage
- Autosomal linkage
- Epistasis
Codominant definition
Alleles are both expressed in the phenotype
Neither one is recessive
How to write alleles which are co-dominant
Cannot use upper and lower case letters for the alleles- this would imply that 1 was dominant to the other
Use different letters and put them as superscripts above a letter that represents the gene
Sex linked gene definition
A gene that is carried on either the X or Y chromosome
Sex linkage:
Females: XX
Males: XY
X chromosome is much longer than Y chromosome which means for most of the length of the X chromosome, there is no equivalent homologous portion of the y chromosome
Because males only have 1 X chromosome, they express the characteristic of this allele even if it’s recessive
Autosome definition
A chromosome that isn’t a sex chromosome
Autosomal linkage definition
Genes on the same chromosome are linked
How does autosomal linkage change the expected phenotypic ratio?
- Genes on same autosome- so will stay together during independent segregation of chromosomes in meiosis 1
- Alleles passed to offspring together
- They do not segregate in accordance with Mendel’s Law of Independent Assortment
- Only reason this won’t happen is if crossing over splits them up first
Epistasis definition
Arises when the allele of 1 gene affects or masks the expression of another in the phenotype
When to use the chi-squared test + what is it:
Used to see whether the results of investigations are significantly different to expected outcomes or whether deviations could be due to chance alone
Use if: have categoric or discrete data, large sample size, raw data (not %)
How to work out degrees of freedom:
Number of classes - 1
In the chi-squared test, when do you accept the null hypothesis?
If probability deviation if greater than the critical value
Means any difference is due to chance and not significant
In the chi-squared test, when do you reject the null hypothesis?
If probably deviation is less than critical value
Any difference is significant
Population definition
A group of organisms of the same species occupying a particular space at a particular time that can potentially interbreed
Gene pool definition
The complete range of alleles in a population
Allele frequency definition
How often an allele occurs in a population
What is the Hardy-Weinberg principle?
A mathematical model which predicts that allele frequencies will not change from generation to generation
The Hardy-Weinberg principle is only true under what conditions?
Has to be:
- Large population
- An isolated population- no immigration or emigration
- Random mating
- No selection- all alleles are equally likely to be passed to the next generation
- No mutations arise