7 Brain Flashcards

1
Q

What makes white vs gray matter

A

White= axons, gray= cell bodies

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2
Q

Pseudounipolar cells: 2, bipolar: 2

A

Pseudo: drg and cranial ganglion, bi: retina, ear

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3
Q

Astrocyte function

A

Metabolic reg and neuron repair

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4
Q

Ependymal cell function

A

Form choroid plexus to make csf, in 3rd and 4th ventricles

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5
Q

Oligodendrocyte function

A

Form myelin sheath in cns

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6
Q

Microglia function

A

Phagocytose debris

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7
Q

Brain part where motor and sensory cortex are

A

Motor: frontal, parietal: sensory

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8
Q

Where in brain you understand vs motor control speech

A

Understand- wernicke, talk- broca

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9
Q

Cognition, sensation, movement area

A

Cerebral cortex

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10
Q

Memory and learning area

A

Hippocampus

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11
Q

Emotion, appetite, response to pain area

A

Amygdala

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12
Q

Fine motor control area

A

Basal ganglia

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13
Q

Areas of autonomic reg

A

Pons and medulla

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14
Q

Cerebellum parts: equilibrium, muscle tone, and voluntary movement

A

Equil: archeo, muscle tone: paleo, neo: voluntary movement

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15
Q

Only cranial nerve that isn’t in pns, how its also diff

A

CN II, surrounded by dura

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16
Q

CSF: volume, specific gravity, and pressure

A

150 ml, 1.002-1.009, 5-15 mmhg

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17
Q

CSF: produced by what/rate

A

Ependymal cells of choroid plexus, 30 ml/hr

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18
Q

CSF circulation path

A

L and R lateral ventricles, foramen of Munro, 3rd vent, aqueduct of sylvius, 4th vent, foramen of luschka (2) and foramen of magendie, brain and SC, superior saggital sinus

19
Q

Where csf is absorbed

A

Arachnoid villi in superior saggital sinus

20
Q

Pneumonic for csf flow

A

Love my 3 silly 4 lorn magpies

21
Q

CBF equation

22
Q

CBF rough amount in ml or % CO

A

50 ml/100g/min or 15%

23
Q

CBF value when: ischemic, cortical suppression, cell death

A

20, 15, <15

24
Q

Determinants of CBF: 5

A

Cmro2, CPP, venous pressure, paco2, pao2

25
Cmro2 value
3.5 ml/02/100g tissue/min
26
% of 02 utilization for electrical activity vs cellular integrity
Electrical: 60%, cellular: 40%
27
How cmro2 decreases with temp, when eeg suppressed
7% per degree c. 18-20 c
28
At what high point in temp does CBF decrease
42 c
29
CPP: autoreg range, calculation
50-150 mmhg. MAP - ICP (or CVP if higher)
30
When happens to vessels when CPP <50 or >150
If less: maximally dilated and risk hypoperfusion. If greater: maximally constricted, pressure dependent, risk hemorrhage/edema
31
If ICP is elevated, CPP requires what to be maintained
A higher MAP
32
Autoreg is abolished by what
IC tumor, head trauma, VAs
33
Conditions that impair venous drainage, ultimate result
Jugular compression from positioning, inc intrathoracic pressure from coughing/peep, VC thrombosis or syndrome. Dec venous drainage and inc CBV
34
Relationship between Paco2 and CBF
Every 1 mmhg inc in co2 above 40 CBF will inc 1-2 ml/100g tissue/min. Also dec if below.
35
Max dilation and constriction at what CO2 levels
Dilation: 80-100, constriction: 25
36
Resp ___ inc CBF, resp ___ dec CBF. What does not affect CBF
Acidosis inc, alkalosis dec. Metabolic acidosis (doesnt cross bbb)
37
PaO2 < what causes cerebral dilation/inc CBF. If above what no effect
<50-60, above 60
38
ICP: nml range, when htn, when its measurement is indicated
5-15, 20, if gcs of 7 or lower
39
S/s of IC htn
HA, NV, papilledema, focal neuro deficit, dec LOC, sz, coma
40
Components that can inc ICP
Brain, blood, csf
41
Cushing triad, what it means
Bradycardia, htn, irreg resp. IC htn
42
Most common site of herniation, inc pressure on what
Temporal uncus, midbrain
43
Sign of temporal uncus herniation
Comp on cn III —> fixed and dilated pupil