7 Flashcards
what sites exist for an allosteric enzyme
active and regulatory
do allosteric enzymes obey michaelis-menten kinetics
no
what kind of activity curves are found for
sigmoidal
what is homotropy/homoallosrery
substrates are effectors
may bind active sites or regulatory sitres
do allosteric enzymes have quaternary structure
many of them yes
describe ATCase
6 catalytic subinits and 6 regulatory
D3 symmetry
first step in CTP biosynthesis
activated by ATP
feedback inhibition
what are feedback inhibitors usually
allosteric modulators
describe the following as homo/hetero inhibitoris/ activatros for ATc
CTP
ATP
aspratate
CTP heterotropic inhibitor
ATP heterotropic activator
asparate homotropic activator
describe the shape of phosphofructokinase
d6 HOMOTETRAMER
describe ATP relationship to phosphofructokinase
homotropic inhibitor
2 binding sites (active and regulatory)
describe fructose-6-phosphate relationship to phosphofructokinase
binds to active site
homotropic activatro
describe AMP relationship to phosphofructokinase
heterotopic(+)
describe phosphoenolpyruvate relationship
heterotropic (-)
what kind of change is reversible covalent modification associated with
tertriary structure change
is glycogen synthase anabolic or catabolic
anabolic