67. Factors and hormones. Toxic shock syndrome during menstruation.

Question 1

hormones effects depend on ?

Answer 1

the circulating concentration
concentration or receptors
the sensitivity of the receptors

Question 2

what are all all the hormones the ovaries secret ?

Answer 2

oestrogen
progesterone
testosterone
inhibin

Question 3

actions of estrogen on vagina ?

Answer 3

epithelilal proliferation

increased in glycogen stores - and feeds the lactic acid producing bacteria naturally occurring in the vagina

Question 4

actions of estrogen on the cervix

Answer 4

increase mucus production

dilation of cervica; canal

Question 5

action of estrogen on uterus

Answer 5

proliferation of the endometrium the functional layer
causes the coiled arteries for angiogensisi
increases myometrial contractility

Question 6

action of estrogen in the fallopian tubes

Answer 6

increases secretion

higher motility

Question 7

effect of estrogen on the lungs ?

Answer 7

increased vital capacity

Question 8

effect of oestrogen on the bone ?

Answer 8

stimulates osteoblasts - bone formation

Question 9

effect of estrogen on skin and connective tissue ?

Answer 9

collagen and mucopolysaccharides

Question 10

effect of estrogen on vascular system ?

Answer 10

vasodilation
activation of RAAS
increased vessel perm

• antihypertensive

Question 11

effect of oestrogen in coagulation

Answer 11

increased coagulation promoting and coagulation inhibiting activity

Question 12

what is the effect of estrogen on fat metabolism

Answer 12

decreased LDL

increased HDL / VLDL

Question 13

action of progesterone on vagina ?

Answer 13

disqualification of epithelial cells

Question 14

action of progesterone on the cervix ?

Answer 14

mucus plug

cervical canal contract

Question 15

what is the action of progesterone on the uterus ?

Answer 15

reduce ontrcatiity

secretary conversion of endometrium

Question 16

what is the action of progesterone on the fallopian tube ?

Answer 16

decreased secretion and contraction

Question 17

what is the action of progesterone on mammary glands ?

Answer 17

development of lactating system

Question 18

what is the action of oestrogen on CNS ?

Answer 18

increased libido and mood lifting

Question 19

action progesteron on CNS ?

Answer 19

sedative

Question 20

action of progesterone on fat metabolism ?

Answer 20

increased LDL

decreased HDL

Question 21

action of androgens ?

Answer 21

libido
increases pubic hair growth
anabolic
mitogenic

Question 22

what inhibits FSH and LH?

Answer 22

dopamine , acetylcholine and opioids

Question 23

what drug causes excretory effect of FSH and LH

Answer 23

noradrenaline

Question 24

where is prolactin produced ?

Answer 24

anterior pituitary

Question 25

where is oxytocin produced ?

Answer 25

nucleus paraventriculus of the hypothalamus

Question 26

bacterial etiology Toxic shock syndrome during menstruatiom

Answer 26

strep progenies

staph aureus

Question 27

what introduced strep pyogenes and stop areas ?

Answer 27

very absorbent tampons

strep pyo - individual with preexisting skin infections

Question 28

signs and symptoms of TSS on staph aureus ?

Answer 28

high fever,

low blood pressure,

confusion-can rapidly progress to stupor, coma

multiple organ failure

characteristic rash, resembling a sunburn

in patients who survive the initial phase the rash desquamatises and peels off after 10-21 days

non purulent conjunctivitis

profuse watery diarrhoea

Question 29

signs and symptoms of TSS on strep ?

Answer 29

same but pain on sight of infection

less sunburn like lesions

Question 30

pathophysiology of TSS

Answer 30

superantigens interact directly with the MHC-II molecules , instead through antigen representing cells

resulting in activation of t cells in mass

causing cytokine storm

leasing the multisysem organ failure

Question 31

what is the treatment of TSS ?

Answer 31

administration to the ICU
fluid managment, ventilation, renal replacement therapy

administer antibiotics
combo of cephalosporins m penicillin and vancomycin if needed