6.4.1 Homeostasis and negative feedback Flashcards
Homeostasis
Homeostasis
Physiological control systems that maintain the internal environment within restricted limits
Temperature
Temperature too high breaks hydrogen bonds, this changes the tertiary shape of the enzyme so the active site will be a different shape and no longer complementary to the substrate
pH
If blood pH too high or low, enzymes become denatured because ionic and hydrogen bonds broken
pH equation
pH = -log10(H+)
Blood glucose concentration
If too high, water potential lowered and water moves out of cells by osmosis. If too low, not enough glucose for respiration
Negative feedback
Normal levels, levels change from normal, receptors detect the change, communication via nervous or hormonal system, effectors respond
Multiple negative feedback mechanisms
Having more than one negative feedback mechanism gives more control over changes
Positive feedback
Amplifies a change away from the normal level, not present in homeostasis but helps rapidly activate processes in body