6.4 - Gas Exchange Flashcards
What is ventilation
Ventilation is the exchange of gases between the atmosphere and the lungs - achieved via inhalation and exhalation
What is Gas Exchange
Involves the transfer of gases between lungs and the blood stream - passive diffusion between alveoli and capillaries
What is cell respiration
involves the release of energy (ATP) from organic molecules - enhanced by the presence of oxygen and produces CO2 as waste
Explain the concentration gradient in ventilation
A ventilation system maintains the concentration gradient needed for passive diffusion of gases.
O2 - ALVEOLI (HIGH) — CAPILLARIES(LOWER)
Co2 - CAPILLARIES(HIGH)—- ALVEOLI(LOWER)
What is the order of how the lung exchanges gas
Air enters via nose or mouth
Air travels down the trachea
Trachea splits into the bronchi
Bronchi forms bronchioles
Bronchioles end in alveoli
Alveoli exchange gases with the bloodstream (capillaries)
What are pneumocytes
cells that line the alveoli and comprise the inner surface of a lung
Describe the characteristics of Type I Pneumocytes
they mediate gas exchange with capillaries and cover 95% of the alveolar surface. Flat & Thin to minimise diffusion distance.
Describe the characteristics of Type II Pneumocytes
Secrets pulmonary surfactant which reduces surface tension in the alveoli, stops the lung from collapsing and creates moist surface inside the alveoli
cuboidal in shape and possess many granules
What is pulmonary surfactant?
decreases surface tension in the alveoli
What does pulmonary surfactant do
enables smaller alveoli to expand, preventing collapse of air spaces
What is Boyle’s Law
When volume in thoracic activity increases, pressure decreases (gas flows in)
- STATE OPPOSITE TOO
What happens during inspiration/inhalation
- External intercostal muscles contract
- Internal intercostal muscles relax
- Diaphragm contracts
- Abdominal muscles relax
- Pressure in the lungs decreases while volume increases, air enters
What happens during expiration/exhalation
- Internal intercostal muscles contract
- External intercostal muscles relax
- Diaphragm relaxes
- Abdominal muscles contract
- Pressure in lungs increases while volume decreases, air escapes
How can exercise influence ventilation patterns?
It can increase ventilation rate (greater frequency of breaths)
It can increase tidal volume (amount of air per breath).
What is lung cancer?
The uncontrolled growth of lung cells leading to tumour formation.