6.19 Steroid Hormones & Vitamin D

Question 1

3-B-Hydroxysteroid Dehydrogenase Deficiency

Answer 1

Virtually no glucocorticoids, mineralocorticoids, active androgens, or estrogens. Salt excretion in urine. Female like genitalia.

Question 2

17-a-Hydroxylase Deficiency

Answer 2

virtually no sex hormones or cortisol, increased production of mineralcorticoids causing sodium and fluid retention, hypertension. female like genitalia.

Question 3

21-a-Hydroxylase Deficiency

Answer 3

Most common form of congenital adrenal hyperplasia, virtually no mineralcorticoids and glucocorticoids, overproduction of androgens resulting in masculinization and virilization.

Question 4

11-B1-Hydroxylase Deficiency

Answer 4

Decrease in serum cortisol, aldosterone, and corticosterone. Fluid retention from increased production of deoxycorticosterone. Overproduction of androgens resulting in masculinization and virilization.