6. VL Flashcards

Drosophila II The Drosophila compound eye: a model system for organogenesis, cell polarity & signal transduction

1
Q

The visual system of Drosophila is made of…

A

2 compound eyes:

~800 ommatidia in regular pattern (image formation) + 3 ocelli (lens, few photoreceptors, pigment cells)

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2
Q

What are the components on an ommatidium?

A

~20 cells, with 8 photo- receptor (R) cells in characteristic pattern
bristle, cornea, pseudocone, cone cells, rhabdomere, photoreceptor, cone cell process, photoreceptor, cone cells, cone cell pedicel, axon, basal lamina

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3
Q

The photoreceptor cells are…

A

…epithelial cells

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4
Q

Some facts about the rhapdomer?

A

~ 30,000 microvilli
= light or waveguide, trapping axially directed light
contains rhodopsin (~1000/microvillus) & the phototransduction machinery
100-μm-long rhabdomere is made up of toothbrush-like stacks of membrane called microvilli.

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5
Q

Major research topics on the Drosophila compound eye are…

A
  • Organogenesis
  • Signaltransduction
  • Development of apico-basal cell polarity
  • Developmentofplanarcellpolarity
  • Phototransduction cascade
  • Loss-of-function mutations
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