6. VL Flashcards
Drosophila II The Drosophila compound eye: a model system for organogenesis, cell polarity & signal transduction
The visual system of Drosophila is made of…
2 compound eyes:
~800 ommatidia in regular pattern (image formation) + 3 ocelli (lens, few photoreceptors, pigment cells)
What are the components on an ommatidium?
~20 cells, with 8 photo- receptor (R) cells in characteristic pattern
bristle, cornea, pseudocone, cone cells, rhabdomere, photoreceptor, cone cell process, photoreceptor, cone cells, cone cell pedicel, axon, basal lamina
The photoreceptor cells are…
…epithelial cells
Some facts about the rhapdomer?
~ 30,000 microvilli
= light or waveguide, trapping axially directed light
contains rhodopsin (~1000/microvillus) & the phototransduction machinery
100-μm-long rhabdomere is made up of toothbrush-like stacks of membrane called microvilli.
Major research topics on the Drosophila compound eye are…
- Organogenesis
- Signaltransduction
- Development of apico-basal cell polarity
- Developmentofplanarcellpolarity
- Phototransduction cascade
- Loss-of-function mutations