6. Varicocele Flashcards
Varicocele
- Definition
- Note
- Etiology
Definition of Varicocele
Elongation, dilatation and tortuosity of the pampiniform plexus of veins or the cremasteric veins, Internal and external spermatic veins
Note on Varicocele
The testicular vein has no valves & the pampiniform plexus has few inefficient valves
Etiology of Varicocele
- Primary Varicocele
2. Secondary Varicocele
Primary Varicocele in Etiology of Varicocele
- INCIDENCE
- AGE
- ETIOLOGY
- SIDE AFFECTED
- CLINICAL PICTURE
- COMPLICATIONS
- INVESTIGATIONS
- TREATMENT
INCIDENCE of Primary Varicocele in Etiology of Varicocele
Its percent in males is about 20%
AGE of Primary Varicocele in Etiology of Varicocele
usually affects young adults (15-30 years).
ETIOLOGY of Primary Varicocele in Etiology of Varicocele
- Its exact cause is not known
- but may be due to congenital weakness of venous walls
- which may be due to familial weakness of mesenchymal tissue
- Associated with hernia, varicose veins, and flat feet
SIDE AFFECTED in Primary Varicocele in Etiology of Varicocele
Primary Varicocele almost always affects the left side
Pathogenesis of Left side affection in SIDE AFFECTED in Primary Varicocele in Etiology of Varicocele
- The right angled termination of the left spermatic vein into the left renal vein, impedes the venous return, in contrast to the oblique termination of the
right vein into the IVC. - The left renal vein passes anterior to the aorta & posterior to the superior mesenteric artery (nutcracker action).
- Ineffective anti-reflux valves at the junction of the testicular vein and renal vein
- The lower position of the left testes & the higher position of the left kidney
- Compression of the left testicular vein by the heavily loaded pelvic colon
CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- Symptoms
* Examination
Symptoms in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- Usually, the condition is asymptomatic.
- Dragging pain
- The patient may complain of infertility.
- Complications may be the 1st presentation
Main symptom in Symptoms in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
The condition is asymptomatic.
Dragging pain in Symptoms in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- what Increase
- what Decrease
- Pathogenesis
what Increase Dragging pain in Symptoms in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- prolonged standing
* hot weather
what Decrease Dragging pain in Symptoms in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
relieved by lying down and during sleep
Pathogenesis of Dragging pain in Symptoms in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
Due to over relaxation of cremasteric and dartos muscles to inc. heat loss as the venous congestion inc. temp
Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- INSPECTION
- PALPATION
- Examine the abdomen to exclude 2ry varicocele.
- GRADING OF VARICOCELE
INSPECTION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- Large varicoceles are also visible.
2. The affected side of the scrotum hangs lower than normal.
PALPATION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- Scrotal neck test
- A bag of worms
- Differentiate between 1ry and 2ry varicocele
- Associated pathology
Scrotal neck test in PALPATION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- Normal Finding
* Abnormal Finding indicating Varicocele
Normal Finding in Scrotal neck test in PALPATION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
Normally only the vas is felt
Abnormal Finding indicating Varicocele in Scrotal neck test in PALPATION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
inguino-scrotal swelling giving a thrill on cough.
A bag of worms in PALPATION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
On standing there are dilated, elongated & tortuous veins felt above the testis like “a bag of worms”.
Differentiate between 1ry and 2ry varicocele in PALPATION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- Primary varicocele empties
* while the patient is lying down and the scrotum is elevated
* by the bow test - Examine the abdomen to exclude 2ry varicocele.
Associated pathology in PALPATION in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
There is often a small 2ry hydrocele.
GRADING OF VARICOCELE in Examination in CLINICAL PICTURE of Primary Varicocele in Etiology of Varicocele
- Grade 0 Varicocele detected by duplex only.
- Grade 1 Varicocele detected by straining.
- Grade 2 Varicocele detected by palpation.
- Grade 3 Varicocele detected by inspection
COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
- subfertility
- Recurrent attacks of thrombophlebitis
- 2ry vaginal hydrocele.
- Anxiety neurosis
- Testicular atrophy (rare)
Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
- Incidence
- Pathology
- Etiology
Incidence of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
15%
Pathology of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
asthenospermia mainly, then oligospermia
Etiology of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
- Thermal theory
- Toxic theory
- Hypoxic theory
- Note
Thermal theory in Etiology of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
Warmth from venous congestion affects spermatogenesis
Toxic theory in Etiology of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
Metabolic substances of steroids & catecholamines are toxic and potentially spermatogenic inhibitors reach the left testicular vein at a higher levels.
Hypoxic theory in Etiology of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
Venous stasis causes hypoxia & lactic acidosis affecting spermatogenesis.
Note on Etiology of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
Subfertility occurs even if the condition is unilateral
The reason why Subfertility occurs even if the condition is unilateral in Note on Etiology of Subfertility in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
due to presence of intercommunicating veins between both testicular veins in the abdomen.
Recurrent attacks of thrombophlebitis in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
- Etiology
* Clinical Picture
Etiology of Recurrent attacks of thrombophlebitis in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
Due to Accumulation of metabolites
Clinical Picture of Recurrent attacks of thrombophlebitis in COMPLICATIONS of Primary Varicocele in Etiology of Varicocele
Stitching pain
INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
- Semen analysis
- Scrotal Duplex scan
- Abdominal U/S
Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
- Normal Findings
- Affected parameters
- Normal grading of motility as mentioned by WHO
- Note
Normal Findings in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
Count 20 - 150 million /ml
Affected parameters in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
Stress triad:
- Motility )> shaking motility
- Count
- increased the abnormal forms
Most prominent parameter in Affected parameters in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
Motility )> shaking motility
Normal grading of motility as mentioned by WHO in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
- Grade a ( fast progressive)
- Grade b ( slowly progressive)
- Grade c (non-progressive or local motility only)
- Grade d (immotile)
- Note
Grade a ( fast progressive) in Normal grading of motility as mentioned by WHO in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
sperm are those which swim forward fast in a straight line-like guided missiles.
Grade b ( slowly progressive) in Normal grading of motility as mentioned by WHO in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
sperm swim forward, but either in a curved or crooked line.
Grade c (non-progressive or local motility only) in Normal grading of motility as mentioned by WHO in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
sperm move their tails only, but do not move forward.
Grade d (immotile) in Normal grading of motility as mentioned by WHO in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
sperm do not move at all.
Note on Normal grading of motility as mentioned by WHO in Semen analysis in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
ln order to give birth, grade (a + b) shoutd be at least 50% as sperms of grade (c & d) are considered poor.
Scrotal Duplex scan in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
- Normal Findings
- Abnormal Findings
- Benefits
Normal Findings in Scrotal Duplex scan in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
Normal diameter of the Spermatic veins
0.8 - 1.2 mm (1 mm)
Abnormal Findings in Scrotal Duplex scan in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
- Reversed blood flow in the Spermatic veins
2. Dilated Spermatic veins ( > 1.5 mm)
Benefits of Scrotal Duplex scan in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
- Detection of subclinical cases of contralateral side
- Detection of Which vein is affected ( internal or external spermatic veins)
- provides full assessment of the testis
- Detects 2ry vaginal hydrocele if present
Abdominal U/S in INVESTIGATIONS of Primary Varicocele in Etiology of Varicocele
For older patients e.g : 40 years old
exclude causes of Secondary Varicocele
e.g. hypernephroma
TREATMENT of Primary Varicocele in Etiology of Varicocele
l- Conservative treatment
ll- Surgical treatment
Conservative treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- In early cases, the patient is reassured.
- For pain, a scrotal support can be used especially in hot weather.
- Advise the patient to take frequent cold baths.
- Advise the patient to avoid sexual congestion & prolonged standing.
Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Indications
- Aim
- Operations & Approaches
Indications of Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Subfertility: After complete exclusion of all other causes of infertility.
- A large painful varicocele )> severe intolerable pain
- Before admission to a military college
Aim of Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Prevention of venous reflux from the left renal vein to the testicular vein is achieved by attacking the venous return of the testis
Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Retroperitoneal approach
- Inguinal approach
- Scrotal approach
- Recent trends
Retroperitoneal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Alternative name
- Principle
- Advantages
- Disadvantages
Alternative name for Retroperitoneal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Palomo’s operation
Principle of Retroperitoneal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Ligation and division of the testicular vein (1 or 2) in the retroperitoneal space as it emerges from the internal ring
Advantages of Retroperitoneal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
No postoperative hydrocele
Disadvantages of Retroperitoneal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Recurrence is common as the cremasteric vein is not ligated
Inguinal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Principle
- Advantages
- Disadvantages
Principle of Inguinal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Ligation and division of the pampiniform plexus of veins together with the cremasteric vein in the inguinal canal
- Excision of a segment of the vein to a avoid recanalization.
- Eversion of the tunica vaginalis is better done routinely
Advantages of Inguinal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Less incidence of recurrence as the cremasteric vein is ligated.
Disadvantages of Inguinal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Postoperative hydrocele is common
The reason why Postoperative hydrocele is common in Disadvantages of Inguinal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
due to interruption of the lymphatic vessels so eversion of the tunica vaginalis is better done routinely
Scrotal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Indication
- Principle
- Advantages
- Disadvantages
Indication of Scrotal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Not recommended by all surgeons
* Suitable for neurotic illiterate patients
Principle of Scrotal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Ligation and division of the pampiniform plexus in the scrotum
- Eversion of the tunica vaginalis is recommended routinely by some surgeons.
Advantages of Scrotal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Removal of the swelling & elevation of the testis
* No recurrence as the cremasteric vein is ligated
Disadvantages of Scrotal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Here the testicular artery is an end artery with higher possibility of injury.
- Postoperative hydrocele is common
The reason why Postoperative hydrocele is common in Disadvantages of Scrotal approach in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
due to interruption of the lymphatic vessels so eversion of the tunica vaginalis is recommended routinely by some surgeons.
Recent trends in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Laparoscopic varicocelectomy .
- Testicular vein embolisation under radiological imaging.
- Sub-inguinal microsurgical varicocelectomy
Sub-inguinal microsurgical varicocelectomy in Recent trends in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Alternative name
- Principle
- Advantages
- Note on postoperative outcome
Alternative name for Sub-inguinal microsurgical varicocelectomy in Recent trends in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Marc Goldstein
Principle of Sub-inguinal microsurgical varicocelectomy in Recent trends in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- The varicocele is ligated at the neck of the scrotum just below the external ring.
- This procedure employs a powerful operating microscope that provides 10.25 power magnification to the tiny 1 millimeter testicular artery.
Advantages of Sub-inguinal microsurgical varicocelectomy in Recent trends in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
- Reliable identification and preservation of the testicular artery and lymphatic channels.
- Reliable identification & Ligation of pampiniform plexus of veins & and cremasteric veins.
Note on postoperative outcome in Sub-inguinal microsurgical varicocelectomy in Recent trends in Operations & Approaches in Surgical treatment in TREATMENT of Primary Varicocele in Etiology of Varicocele
Postoperatively, venous return is via the vasal veins, which drain into the internal pudendal system and usually have competent valves
Secondary Varicocele in Etiology of Varicocele
- INCIDENCE
- ETIOLOGY
- CLINICAL FEATURES
- TREATMENT
INCIDENCE of Secondary Varicocele in Etiology of Varicocele
This is a rare condition
ETIOLOGY of Secondary Varicocele in Etiology of Varicocele
due to obstruction of the venous flow in the
spermatic vein by :
- Iatrogenic cause
- Hypernephroma
- Abdominal or pelvic tumour.
- Retroperitoneal fibrosis.
Iatrogenic cause in ETIOLOGY of Secondary Varicocele in Etiology of Varicocele
- actually the most common cause
* During hernia surgery During narrowing of internal ring
Hypernephroma in ETIOLOGY of Secondary Varicocele in Etiology of Varicocele
- as the malignant cells form a malignant thrombus inside the renal vein
i. e. permeation of the renal vein
CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
Difference between primary varicocele and Secondary varicocele
Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
- Age
- Side
- Course
- Effect of Lying down or scrotum elevation
- Abdominal Examination and U/S
- Abdominal
Age of primary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
usually affects young adults (15-30 years).
Age of Secondary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
It occurs after the age of 40 years.
Side of primary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
almost always affects the left side
Side of Secondary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
It affects both sides equally
Course of primary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
Prolonged course
Course of Secondary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
It develops rapidly and enlarges in a few weeks
Effect of Lying down or scrotum elevation of primary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
It disappears on lying down or when the scrotum is elevated
Effect of Lying down or scrotum elevation of Secondary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
It does not disappear on lying down or when the scrotum is elevated
Abdominal Examination and U/S of primary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
No abnormality detected
Abdominal Examination and U/S of Secondary varicocele in Difference between primary varicocele and Secondary varicocele in CLINICAL FEATURES of Secondary Varicocele in Etiology of Varicocele
- Hypernephroma
- Abdominal or pelvic tumour.
- Retroperitoneal fibrosis.
Treatment of Secondary Varicocele in Etiology of Varicocele
Treatment of the cause