Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Reproduction Week 2 2018/19 > 6: STIs > Flashcards

6: STIs Flashcards

1
Q

What is the most common STI in the UK?

A

Chlamydia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How does Chlamydia appear on a Gram stain?

A

Gram negative

But it’s very difficult to stain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is a rare consequence of chlamydia infection?

A

Pelvic inflammatory disease (PID)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What type of bleeding occurs in chlamydia infection?

A

Post-coital and intermenstrual bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How does chlamydia present in females?

A

Post-coital / intermenstrual bleeding

Mucopurulent discharge

Abdominal pain

Dyspareunia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How does chlamydia present in males?

A

Urethral discharge

Dysuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Apart from PID, what are other complications of chlamydia infection?

A

Tubal damage –> infertility

Neonatal transmission (look out for conjunctivitis)

Reiter’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What rheumatological condition can people get following chlamydia infection?

A

Reactive arthritis

i.e Reiter’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Chlamydia is more common in (men / women).

A

women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which variant of chlamydia is more severe than average and presents primarily in MSM?

A

Lymphogranuloma venereum (LGV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

LGV is primarily found in MSM.

What are the symptoms?

A

Rectal pain / discharge / bleeding

often misdiagnosed as GI problem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Chlamydia is likely to ___ with other STIs.

A

coexist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

When is chlamydia tested for?

A

14 days following exposure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the NAAT tests used to detect chlamydia, 14 days after exposure, in

a) men
b) women?

A

a) First pass urine sample +/- rectal swab

b) Vulvovaginal swab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is chlamydia treated?

A

Doxycycline 100mg BD 1/52

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which antibiotic is used second-line for chlamydia infection?

A

Azithromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

How does Neisseria gonorrhoeae appear on a Gram stain?

A

Gram negative intracellular diplococci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the incubation time of gonorrhoea?

A

2 - 5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Gonorrhoea is more common in (men / women).

A

men

as opposed to chlamydia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

How does gonorrhoea present in men?

A

Purulent urethral discharge

Dysuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

WHERE must you swab in men with suspected gonorrhoea infection?

A

Urethra

Rectum

Pharynx…

all the sites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What percentage of women have gonorrhoea and are asymptomatic?

How do they present otherwise?

A

50%

Vaginal discharge, pelvic pain

23
Q

How is gonorrhoea screened for?

A

NAAT testing

First pass urine in men, VV swab in women

Concurrently tests for chlamydia

24
Q

How is gonorrhoea investigated in patients who are symptomatic?

A

Culture

25
Q

How is gonorrhoea treated?

A

Ceftriaxone 500mg IM

26
Q

How is gonorrhoea treated if an IM injection of ceftriaxone is rejected by the patient?

A

Cefixime 400mg PO

27
Q

What must be done two weeks after antibiotic treatment in all patients with gonorrhoea?

A

Test of cure

28
Q

What is the presentation of a primary infection of genital herpes?

A

Extreme pain

Blistering and ulceration of genitalia

Dysuria

Discharge (urethral / vaginal)

Enlarged inguinal lymph nodes

Viral prodrome (fever and myalgia)

29
Q

Which subtype of HSV causes recurrent genital herpes?

A

HSV-2

30
Q

How often does genital herpes recur when the causal agent is

a) HSV-1
b) HSV-2?

A

a) Every 1-2 years

b) Every 2-3 months

31
Q

Genital herpes tends to recur (more / less) often over time.

A

less often

disease burns itself out

32
Q

How is genital herpes investigated?

A

Swab of deroofed lesions for viral PCR

33
Q

What drugs are used in the treatment of genital herpes?

A

To treat: Aciclovir 400mg TDS 5/7 PO

For pain: topical lidocaine

34
Q

Which subtype of HSV sheds more often and causes more recurrent genital herpes?

A

HSV-2

35
Q

What drugs can be given for highly recurrent HSV-2 to prevent recurrence and transmission?

A

Aciclovir 400mg BD for a year

Check this

36
Q

Why is genital herpes in the 3rd trimester of pregnancy concerning?

A

Chance of neonatal herpes

37
Q

What is the most common viral STI in the UK?

A

HPV

80% of people will have it

38
Q

HPV has a ton of subtypes.

Which cause

a) low risk disease (e.g genital warts)
b) high risk disease (e.g cancer)?

A

a) 6 & 11

b) 16 & 18

39
Q

Which presentations of HPV are caused by

a) HPV 6 & 11

b) HPV 16 & 18?

A

a) Anogenital warts

b) Cancers

40
Q

Which drugs are used to kill off genital warts topically?

A

Podophyllin first-line

Imiquimod second-line

41
Q

Apart from podophyllin and imiquimod, what treatment options exist for genital warts?

A

Cryotherapy

Electrocautery

42
Q

Who is vaccinated against HPV?

A

11 - 13 year old girls

MSM

(School-age boys are going to be included soon)

43
Q

Which bug causes syphilis?

A

Treponema pallidum

44
Q

What does treponema pallidum look like on microscopy?

A

Spirochaete

45
Q

Which stages of syphilis are

a) infectious
b) non-infectious?

A

a) Primary, secondary and early latent

b) Late latent and tertiary

46
Q

How long does syphilis incubate for before a chancre appears?

A

21 days on average

47
Q

What is a chancre?

A

Painless ulcer of primary syphilis

48
Q

What is the presentation of secondary syphilis?

A

Rashes

Snail-track ulcers

Lymphadenopathy

Alopecia

49
Q

What is condylomata lata?

A

V infectious skin lesion of secondary syphilis

50
Q

Why is syphilis referred to as the great imitator?

A

Mimics many other diseases (skin, pharynx, rectum, mucous membranes…)

51
Q

What are two investigations used for syphilis?

A

Viral swab –> PCR

Serology

52
Q

Which drug is used to treat syphilis?

A

Benzathine penicillin IM

53
Q

What is Reiter’s syndrome?

A

Triad of arthritis, conjunctivitis and urethritis

Commonly seen after GU and GI infections e.g chlamydia and gonorrhoea

Reproduction Week 2 2018/19 (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions