6: Host infection interactions Flashcards
Which cells of the skin secrete antimicrobial peptides?
Keratinocytes
Which glands of the skin secrete antimicrobial peptides?
Sebaceous glands
What are the antigen presenting cells of the skin?
Langerhans cells
What is the antibody mainly found on mucosal surfaces?
IgA
What complication of chemotherapy can cause GI infection and sepsis?
Mucositis
Which immune cells are mainly responsible for killing bacteria and fungi?
Phagocytes
macrophages, neutrophils
A deficiency in T lymphocytes makes you susceptible to infections by which organisms?
Viruses
Fungi
Parasites
intracellular organisms
Which immune cells does HIV target?
CD4+ T cells
What do
a) B cells mature into
b) monocytes mature into?
a) Plasma cells
b) Macrophages
Which biologic agent suppresses B cells?
Rituximab
HIV infection puts you at risk of which particular infection?
It also puts you at risk of ___ infections.
Strep. pneumoniae
Atypical infections
What problem with the spleen can cause infection?
Hyposplenism
What are some causes of hyposplenism?
Splenectomy
Sickle cell, autoimmune stuff (check this)
___ patients are more likely to have opportunistic infections.
Do they show the same signs and symptoms as normal people?
Immunocompromised
Noooooo
What can be given to patients to reduce their risk of infection?
Prophylaxis (rarely)
Vaccination
