6. Hormones Mode Of Action Flashcards
What system regulates hormone secretion?
Negative feedback system
What do endocrine system cells respond to? (3)
Changes in the cellular environment
Stimulation by nerves
Other hormones
Which chemical families work from outside the cell? Why?
Protein and amine
Not lipid soluble - can’t penetrate the phospholipid bilayer
Which chemical families work from inside the cell?
Amine
Are lipid soluble - can penetrate the phospholipid bilayer
Proteins and amines bind to the cell m_______, and receptors act as a f____ m________
Membrane
First messenger
Where do amines bind to a receptor? (2)
Nucleus or mitochondria
Target cells respond to the first messenger by producing a second messenger. Give an example of a second mesenger
cAMP - cyclic Adenosine MonoPhosphate
when steroids are picked up by receptor molecules, they are taken to the nucleus to act on specific g____ therefore new cell function is i________ or a______ when appropriate genes are turned on or off.
Genes
Initiated or altered
Steroids change g______ m_______ whereas p_______ and amines change the m_________.
Genetic material
Proteins
Metabolism