6 - Exchange (Digestion) Flashcards

1
Q

what is the biggest keyword for this topic?

A

HYDROLYSE/ HYDROLYSIS

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2
Q

what is physical breakdown

A

breaking food down into smaller pieces using mechanical structures (eg. teeth, stomach walls)

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3
Q

how is food physically broken down in stomach?

A

food is churned by muscle in stomach wall

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4
Q

benefit of physical breakdown

A
  • provide large SA for chemical digestion
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5
Q

what is chemical digestion?

A

HYDROLYSES large, insoluble molecules into smaller soluble ones

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6
Q

what is hydrolysis?

A

process of splitting up molecules by adding water to chemical bonds that hold them together

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7
Q

three main types of digestive enzymes

A
  • carbohydrases
  • lipase
  • proteases
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8
Q

where is amylase produced?

A
  • salivary glands
  • pancreas
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9
Q

function of amylase

A
  • hydrolyses alternate glycosidic bonds of starch molecule
  • produce the disaccharide maltose
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10
Q

what is maltase?

A
  • membrane bound disaccharidase
  • produced in lining of ileum
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11
Q

function of maltase

A
  • hydrolyse maltose into monosaccharide a-glucose
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12
Q

common disaccharides in the diet

A
  • maltose (eg. starch)
  • sucrose (eg. fruits)
  • lactose (eg. milk products)
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13
Q

function of sucrase

A
  • hydrolyses single glycosidic bond in sucrose molecule
  • produces gluc + fruc
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14
Q

function of lactase

A
  • hydrolyses single glycosidic bond in lactose molecule
  • produces gluc + galac
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15
Q

endopeptidase function

A
  • hydrolyse internal peptide bonds between amino acids
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16
Q

exopeptidase function

A
  • hydrolyse peptide bonds between terminal amino acids of peptide molecules
  • … peptide molecules FORMED BY endopeptidases
17
Q

why combined actions of endopeptidases and exopeptidases more efficient than exopeptidases on their own?

A
  1. endopeptidases hydrolyse internal peptide bonds and exopeptidases remove amino acids/hydrolyse peptide bonds at end
  2. more ends or increase in surface area for exopeptidases
18
Q

dipeptidase function

A
  • hydrolyse peptide bond between two amino acids of a dipeptide
  • membrane bound
19
Q

what membrane are membrane bound enzymes bound to?

A
  • cell surface membrane of epithelial cells
  • lining the ileum
20
Q

adaptations of ileum

A
  • folded villi surface
  • thin walled
  • contain muscles
  • well supplied with blood vessels
  • villi -> microvilli
21
Q

function of ileum

A

absorbing products of digestion

22
Q

DESCRIBE process of absorption of products of starch digestion

A
  • glucose moves in with sodium into epithelial cell through symport
  • sodium removed (from epithelial cell) by active transport through sodium- potassium pump into blood
  • maintaining low concentration of sodium in epi. cell so steep conc. grad. between lumen and epi. cell.
  • glucose moves into blood by facilitated diffusion
23
Q

lipase function

A
  • hydrolyses ester bond in triglyceride
  • forms monoglycerides (ie. glycerol) and fatty acids
24
Q

advantage of lipid droplets

A
  • increase surface areas for lipase
  • faster hydrolysis of triglyceride
25
advantage of micelle
- carry fatty acids and monoglyceride through membrane into epithelial cell
26
how does monoglyceride and fatty acids get through membrane of epithelial cell?
- micelle hit epithelia cell (releasing mono and fatty) - simple diffusion - because they are NON POLAR
27
what does endoplasmic reticulum have to do with absorption of triglyceride?
monoglycerides and fatty acids RECOMBINED to form triglyceride
28
what does golgi have to do with absorption of triglycerides?
- modifies/ processes triglycerides - triglycerides associates with lipoproteins and cholestrol - forms vesicles for exocytosis = CHYLOMICRONS
29
how do chylomicrons leave epithelial cell?
- exocytosis - because too big to be diffused etcetc
30
where do chylomicrons go after leaving epithelial cell?
- enter lymphatic capillaries (LACTEALS) - eventually bloodstream
31
describe the induced-fit model of enzyme action
1. before reaction active site not complementary to substrate 2. Shape of active site changes as substrate binds and as enzyme-substrate complex forms 3. distorting bonds in substrate, leading to reaction
32
what is keyword for changes in carrier protein structure (eg. sodium potassium pump)
conformational change