5th practical Flashcards
What is this and what species?
Cholangiohepatitis, cat
Liver
Cholangiohepatitis
Portal triad- hepatic artery
Portal vein
Bilary structure with epithelial cells
limiting phase
Cholangiohepatitis
Cholangiohepatitis
Liver parenchyma
Cholangiohepatitis
Inflammatory cell accumulation- monocell not nucleophiliic are lymphocytes
Bile duct proliferarion
Cholangiohepatitis
Cholangiohepatitis
Rubarth’s disease
Canine adenovirus 1 hepatitis
Rubarths disease
Dogs normally vaccinated today
liver enlarged and shiny and rounded borders
Portal and sinusoidal inflammatory infiltration
Cowdry A-type intranuclear inclusion body
Inflammatory cells and necrosis + eosinophillic cells
Rubarths disease
Rubarths disease
Necrosis nuclei split up and apoptotoic
Confluent necrosis
Rubarths disease
Rubarths disease
Rubarths disease
Rubarths disease
Hyperrimic rim and necrotic
centrilobular and mid zona necrosis
What is caused below the line?
Rubarths disease
Necrosis below line due to viral effect
Black arrows are intranuclear inclusion bodies
Liver cirrhosis
What is the organ and cause?
Liver Cirrhosis
with regenerative anaemia
Chronic condition
scar tissue accumulation in liver cell parenchyma
More coomon in humans due to alcoholism
hepatitis b or c too
Liver cirrhosis with pseudolubolus
nodules seen on cut surface
scar tissue proliferation splitting pseudolobules invading liver lobules
Liver cirrhosis
Liver cirrhosis with azan staining
blue seperating pseudolobule
Pseudolobule
Liver Cirrhosis
inflammation
azan staining
Liver Cirrhosis
and bile duct proliferation
liver cirrhosis
liver cirrhosis
Gömöri Silver
impregnation
liver cirrhosis
black sperates pseudolobules
Paratuberculosis (cattle, ileum)
cachexia long incubation time
years for clinical manifestation
diarrohea losing weight and mesenteric lymph node enlargement
Paratuberculosis ileum cattle
Paratuberculosis ileum
Paratuberculosis ileum
enteric mucosa and lack of TnA PRODUCTION
No granuloma formation
Paratuberculosis ileum
Paratubeculosis ileum
Seen in the histocytes of the epitheliloid cells
Paratuberculosis ileum
Parvoviral necrotic-haemorrhagic
enteritis (dog, small intestine)
Necrosis of intestines and payers patches is sunken in
Parvoviral necrotic-haemorrhagic
enteritis (dog, small intestine)
Parvoviral necrotic-haemorrhagic
enteritis (dog, small intestine)
Necrosis in the crypts internuclei inclusion bodies
Parvoviral necrotic-haemorrhagic
enteritis (dog, small intestine)
Later stages profileration of mitosis
Parvoviral necrotic-haemorrhagic
enteritis (dog, small intestine)
payers patches top pic
Target for virus centre for lymphoid cell
Lymphoid depletion
Parvoviral necrotic-haemorrhagic
enteritis (dog, small intestine)
Muscular and epithelial layer seen
Parvoviral enteritis
Inflammatory cells seen
What disease is this?
Acute purulent leptomeningitis (pig)
Glaesserella parasuis /
Streptococcus suis
Acute purulent leptomeningitis (pig)
Glaesserella parasuis /
Streptococcus suis
Pia matter is thickened and gyri of brain and acute inflaamation and dilated blood vessels
Acute purulent leptomeningitis (pig)
Glaesserella parasuis /
Streptococcus suis
Inflammatory cells accumulated and neutrophil accumulation
Acute purulent leptomeningitis (pig)
Glaesserella parasuis /
Streptococcus suis
neutrophil granulocytes and thrombosis some degenerated
Encephalitis caused by Listeria monocytogenes
Eating from contaminated food gets into bloodstream and nerves
reach medulla oblongata
(goat, HE)
Encephalitis caused by Listeria monocytogenes
Meninges not affected compared to lepto
perivascular cuffing here
Mononuclear non neutrophillic inflammator cells
neutrophil infiltrates microabsceses
(goat, HE)
Encephalitis caused by Listeria monocytogenes
Lymphocytes and macrophages
(goat, HE)
Encephalitis caused by Listeria monocytogenes
(goat, HE)
What disease is this?
West Nile viral encephalitis, horse
Perivascular and inflammatory cells
around blood vessels
affect neurons too and phagocytos
degenerated neurons removed and replaced by glial cells(pq)
West Nile viral encephalitiGlail scarrings, horse