4th Practical Flashcards
Name organ and type of disease and species?
Bronchopneumonia catarrhalis from pigs
Organ and describe?
Normal lung tissue
alveoli and bronchioli are clean
Airways filled with inflammatory cells
Bronchopneumonia
Inflammation affects alveoli and terminal bronchi
bronchiolitis obliterans
filled with inflammatory cells neutrophil granulocytes
Small bronchiole without cartilage with inflammatory exudate with neutrophil granulocyte
polymorphonuclear cell
desquamated alveolar epithelial cells
upon damage they detach from basement membrane and become huge round cells
Neutrophil granulocytes and lymphoid cells also seen!
epithelisation, type-2 pneumocytes
if cells survive they will try to rebuild with basement membrane
Name the disease?
Pneumonia crouposa
or we can call it bronchopneumonia Crouposa
Damage of the vascular blood vessel is so severe that macromolecules like fibrinogen are able to come out of circulation and polymerize into fibrin
What is 2 hallmark of this disease?
They are always covered by fibrinous pleuritis
Rabbit lung tissue
seen on parietal surface too
also liver like texture on surface
Pleuritis
Inflammatory cells
Pneumonia crouposa
Pneumonia Crouposa
Blood vessels having large thrombi in them
Presence of fibrin in the alveoli
Croupous pneumonia
fibrin staining blue strands
Pneumonia and pleuritis caused by Actinobacillus
pleuropneumoniae
in swine older animals
circumscribed lesions and pleuritis
cut surface 2nd pic
Actinobacillus pleuropneumoniae
Perifocal are marked oedema and hyperaemia
Fibrin rich
Macrophage proliferation in the lumen of the alveoli hallmark part of the disease
Actinobacillus pleuropneumoniae
Macrophage degeneration with bezoar proliferation with 3rd pic arrows
Actinobacillus pneuropneumoniae
oedema and red blood cells evident with bleeding and hemorrhage in lung tissue due to toxins released from bacteria
Interstitial pleuropneumoniae
airways clean infammatory cells not found in the airways but found in the interalveolar septae
due to viral infection same with covid!
Interstitial pleuropneumoniae
Parasites! migrating in the interstitial causing pneumoniae with inflammatory cells (eosinophil!)
kidney histology
Oxolate nephrosis
Ethylene glycol poisoning(antifreeze)
Cats sensitive
Converted to oxolate acid combines with Ca to form oxolate crystals in tubuli of kidney
Oxolate nephrosis
Tubulonephrosis lily poisoning in cats
cells sensitive to hypoxia
Oxolate nephrosis
Crystals seen
exudative glomerulonephritis
Deposition of immune complexes(antigens and antibodys) prolonged infection in the wall of small capillarys in the glomeruli!
pink protein rich exudate
exudative glomerulonephritis
Neutrophil granuloctes seen
exudative glomerulonephritis
Thickening of bowmans capsule and proteinuria
Exudative glomerulonephritis
Protein rich glomeruli
Exudative glomerulonephritis
bowmans capsule thick and proteinuria
Interstitial nephritis
inflammatory cells found in the intertubular space
In flammation cells are mononuclear lymphocytes plasma cells and macrophages
Interstitial nephritis
eosinophil granulocytes seen
Interstitial nephritis
Kidney fibrosis
firm kidney smaller than normal
Kidney fibrosis
Kidney fibrosis